JP2021514206A5 - - Google Patents

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Publication number
JP2021514206A5
JP2021514206A5 JP2020566543A JP2020566543A JP2021514206A5 JP 2021514206 A5 JP2021514206 A5 JP 2021514206A5 JP 2020566543 A JP2020566543 A JP 2020566543A JP 2020566543 A JP2020566543 A JP 2020566543A JP 2021514206 A5 JP2021514206 A5 JP 2021514206A5
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JP
Japan
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domain
human
binding
cancer
cells
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Application number
JP2020566543A
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English (en)
Japanese (ja)
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JP7539840B2 (ja
JPWO2019164929A5 (https=
JP2021514206A (ja
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Priority claimed from PCT/US2019/018748 external-priority patent/WO2019164929A1/en
Publication of JP2021514206A publication Critical patent/JP2021514206A/ja
Publication of JP2021514206A5 publication Critical patent/JP2021514206A5/ja
Publication of JPWO2019164929A5 publication Critical patent/JPWO2019164929A5/ja
Priority to JP2024135326A priority Critical patent/JP2024170430A/ja
Application granted granted Critical
Publication of JP7539840B2 publication Critical patent/JP7539840B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020566543A 2018-02-20 2019-02-20 Cd33を標的とする抗体可変ドメイン及びその使用 Active JP7539840B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024135326A JP2024170430A (ja) 2018-02-20 2024-08-14 Cd33を標的とする抗体可変ドメイン及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862632756P 2018-02-20 2018-02-20
US62/632,756 2018-02-20
PCT/US2019/018748 WO2019164929A1 (en) 2018-02-20 2019-02-20 Antibody variable domains targeting cd33, and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024135326A Division JP2024170430A (ja) 2018-02-20 2024-08-14 Cd33を標的とする抗体可変ドメイン及びその使用

Publications (4)

Publication Number Publication Date
JP2021514206A JP2021514206A (ja) 2021-06-10
JP2021514206A5 true JP2021514206A5 (https=) 2022-03-10
JPWO2019164929A5 JPWO2019164929A5 (https=) 2022-03-10
JP7539840B2 JP7539840B2 (ja) 2024-08-26

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ID=67688433

Family Applications (2)

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JP2020566543A Active JP7539840B2 (ja) 2018-02-20 2019-02-20 Cd33を標的とする抗体可変ドメイン及びその使用
JP2024135326A Pending JP2024170430A (ja) 2018-02-20 2024-08-14 Cd33を標的とする抗体可変ドメイン及びその使用

Family Applications After (1)

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JP2024135326A Pending JP2024170430A (ja) 2018-02-20 2024-08-14 Cd33を標的とする抗体可変ドメイン及びその使用

Country Status (16)

Country Link
US (1) US20200376034A1 (https=)
EP (1) EP3755348A4 (https=)
JP (2) JP7539840B2 (https=)
KR (1) KR20200133222A (https=)
CN (1) CN111989109A (https=)
AU (1) AU2019225740A1 (https=)
BR (1) BR112020016944A2 (https=)
CA (1) CA3091764A1 (https=)
CL (2) CL2020002143A1 (https=)
EA (1) EA202091976A1 (https=)
IL (1) IL276776A (https=)
MX (1) MX2020008683A (https=)
PE (1) PE20211224A1 (https=)
SG (1) SG11202007943RA (https=)
TW (1) TW201945390A (https=)
WO (1) WO2019164929A1 (https=)

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Publication number Priority date Publication date Assignee Title
SG11201907299XA (en) 2017-02-08 2019-09-27 Dragonfly Therapeutics Inc Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
IL268755B2 (en) 2017-02-20 2025-12-01 Dragonfly Therapeutics Inc Proteins that bind her2, nkg2d, and cd16
EA202091887A1 (ru) 2018-02-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры
DK3749346T3 (da) 2018-02-08 2024-09-09 Dragonfly Therapeutics Inc Antistof variable domænekombinationer rettet mod nkg2d-receptoren
WO2019164930A1 (en) * 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
JOP20190116A1 (ar) 2018-05-24 2019-11-24 Janssen Biotech Inc الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
EA202091977A1 (ru) * 2018-05-28 2021-02-09 Драгонфлай Терапьютикс, Инк. Мультиспецифические связывающие белки, которые связывают cd33, nkg2d и cd16, и способы применения
WO2020033630A1 (en) 2018-08-08 2020-02-13 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
US12378318B2 (en) 2018-08-08 2025-08-05 Dragonfly Therapeutics, Inc. Proteins binding NKG2D, CD16 and a tumor-associated antigen
EP3962527A4 (en) 2019-04-30 2023-11-01 Senti Biosciences, Inc. CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
MX2022004430A (es) * 2019-10-15 2022-07-19 Dragonfly Therapeutics Inc Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), al cumulo de diferenciacion 16 (cd16) y a la tirosina cinasa 3 similar a fms (flt3).
MX2022013944A (es) * 2020-05-06 2022-11-30 Dragonfly Therapeutics Inc Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), cumulo de diferenciacion (cd16) y miembro a de la familia de dominios de lectina tipo c 12 (clec12a).
EP4291233A4 (en) * 2021-02-10 2025-05-21 Wugen, Inc. POLYPEPTIDES AND THEIR USE IN THE TREATMENT OF DISEASES
JP2024508894A (ja) 2021-03-03 2024-02-28 ドラゴンフライ セラピューティクス, インコーポレイテッド Nkg2d、cd16、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法
US20250082681A1 (en) * 2021-07-30 2025-03-13 Nanjing Legend Biotech Co., Ltd. Antibodies against cll1 and constructs thereof
WO2023015322A1 (en) * 2021-08-06 2023-02-09 Actinium Pharmaceuticals, Inc. Radioconjugates targeting cd33 in the treatment of cancers
WO2023056252A1 (en) * 2021-09-29 2023-04-06 Dragonfly Therapeutics, Inc. Proteins binding nkg2d, cd16 and baff-r
CN118591388A (zh) * 2021-09-29 2024-09-03 摩德斯医疗股份有限公司 抗原结合多肽、抗原结合多肽复合物及其使用方法
US20250381255A1 (en) * 2022-02-17 2025-12-18 Anokion Sa Anti-asgr1 polypeptides and methods of use for immune tolerance
WO2024249235A1 (en) * 2023-06-01 2024-12-05 Abbvie Inc. Anti-human cd33 bet degrader antibody-drug conjugates
WO2025233431A1 (en) * 2024-05-07 2025-11-13 Immatics Biotechnologies Gmbh Heteromeric proteins comprising three heteromerization improving substitution, production, combinations and applications thereof

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
AU7676300A (en) * 1999-10-12 2001-04-23 Cambridge Antibody Technology Limited Human anti-adipocyte monoclonal antibodies and their use
JOP20080381B1 (ar) * 2007-08-23 2023-03-28 Amgen Inc بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
UA112062C2 (uk) * 2010-10-04 2016-07-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Cd33-зв'язувальний агент
US20130309223A1 (en) * 2012-05-18 2013-11-21 Seattle Genetics, Inc. CD33 Antibodies And Use Of Same To Treat Cancer
EA201691214A1 (ru) * 2013-12-13 2016-12-30 Дженентек, Инк. Антитела к cd33 и иммуноконъюгаты
CN107708733B (zh) * 2015-04-07 2022-11-15 艾利妥 抗分拣蛋白抗体和其使用方法
JP7497953B2 (ja) * 2015-06-12 2024-06-11 アレクトル エルエルシー 抗cd33抗体及びその使用方法
JP7376977B2 (ja) * 2015-06-12 2023-11-09 アレクトル エルエルシー 抗cd33抗体及びその使用方法

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