JP2021513865A5 - - Google Patents

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Publication number
JP2021513865A5
JP2021513865A5 JP2020544642A JP2020544642A JP2021513865A5 JP 2021513865 A5 JP2021513865 A5 JP 2021513865A5 JP 2020544642 A JP2020544642 A JP 2020544642A JP 2020544642 A JP2020544642 A JP 2020544642A JP 2021513865 A5 JP2021513865 A5 JP 2021513865A5
Authority
JP
Japan
Prior art keywords
streptococcus
group
amino acid
modified lysin
lysin polypeptide
Prior art date
Application number
JP2020544642A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019165454A5 (https=
JP2021513865A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/019638 external-priority patent/WO2019165454A1/en
Publication of JP2021513865A publication Critical patent/JP2021513865A/ja
Publication of JP2021513865A5 publication Critical patent/JP2021513865A5/ja
Publication of JPWO2019165454A5 publication Critical patent/JPWO2019165454A5/ja
Pending legal-status Critical Current

Links

JP2020544642A 2018-02-26 2019-02-26 修飾PlySs2溶解素及びその使用 Pending JP2021513865A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862635515P 2018-02-26 2018-02-26
US62/635,515 2018-02-26
PCT/US2019/019638 WO2019165454A1 (en) 2018-02-26 2019-02-26 Modified plyss2 lysins and uses thereof

Publications (3)

Publication Number Publication Date
JP2021513865A JP2021513865A (ja) 2021-06-03
JP2021513865A5 true JP2021513865A5 (https=) 2022-02-09
JPWO2019165454A5 JPWO2019165454A5 (https=) 2022-02-09

Family

ID=67687985

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020544642A Pending JP2021513865A (ja) 2018-02-26 2019-02-26 修飾PlySs2溶解素及びその使用

Country Status (12)

Country Link
US (1) US20210032294A1 (https=)
EP (1) EP3758738A4 (https=)
JP (1) JP2021513865A (https=)
KR (1) KR20200124724A (https=)
CN (1) CN112118861A (https=)
AU (1) AU2019224160A1 (https=)
BR (1) BR112020017219A2 (https=)
CA (1) CA3092109A1 (https=)
IL (1) IL276807A (https=)
MX (1) MX2020008860A (https=)
RU (1) RU2020128276A (https=)
WO (1) WO2019165454A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020210691A1 (en) * 2019-04-11 2020-10-15 Contrafect Corporation Method of treating and preventing bone and joint infections
US20230277632A1 (en) * 2020-05-19 2023-09-07 Contrafect Corporation MODIFIED PlySs2 LYSINS AND ANTIBIOTIC COMBINATIONS FOR USE AGAINST GRAM-POSITIVE BACTERIA
WO2023049747A1 (en) * 2021-09-22 2023-03-30 Elanco Us Inc. Streptococcus suis lytic enzyme compositions and methods of use thereof
WO2023081691A1 (en) * 2021-11-04 2023-05-11 Contrafect Corporation Method of treating and preventing bone and joint infections
CN115851689A (zh) * 2022-08-09 2023-03-28 中南民族大学 一种嵌合裂解酶PlySs2E-V12C及其应用、重组质粒和重组菌株

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2699253T3 (en) * 2011-04-21 2018-07-16 Univ Rockefeller STREPTOCOCCUS BACTERYPHAGIC LYSINES FOR THE DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIES
DK3085777T3 (da) * 2011-05-04 2020-02-03 Micreos Human Health Bv Polypeptid
RU2018121290A (ru) * 2012-05-09 2019-03-06 Контрафект Корпорейшн Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий
BR112014027818B1 (pt) * 2012-05-09 2023-03-28 Contrafect Corporation Usos de composições compreendendo polipeptídeo de lisina para prevenção, ruptura ou tratamento de um biofilme bacteriano
CN104073478A (zh) * 2014-06-13 2014-10-01 上海交通大学 杀灭革兰氏阳性菌的酶抗生素及其制备、用途
CN104211781A (zh) * 2014-09-04 2014-12-17 北京纳百景弈生物科技有限公司 金黄色葡萄球菌裂解蛋白的制备方法及其应用
EP3454888B1 (en) * 2016-05-12 2021-02-24 Contrafect Corporation Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides

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