JP2021513865A5 - - Google Patents

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Publication number
JP2021513865A5
JP2021513865A5 JP2020544642A JP2020544642A JP2021513865A5 JP 2021513865 A5 JP2021513865 A5 JP 2021513865A5 JP 2020544642 A JP2020544642 A JP 2020544642A JP 2020544642 A JP2020544642 A JP 2020544642A JP 2021513865 A5 JP2021513865 A5 JP 2021513865A5
Authority
JP
Japan
Prior art keywords
streptococcus
group
amino acid
modified lysin
lysin polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020544642A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021513865A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/019638 external-priority patent/WO2019165454A1/en
Publication of JP2021513865A publication Critical patent/JP2021513865A/ja
Publication of JP2021513865A5 publication Critical patent/JP2021513865A5/ja
Pending legal-status Critical Current

Links

JP2020544642A 2018-02-26 2019-02-26 修飾PlySs2溶解素及びその使用 Pending JP2021513865A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862635515P 2018-02-26 2018-02-26
US62/635,515 2018-02-26
PCT/US2019/019638 WO2019165454A1 (en) 2018-02-26 2019-02-26 Modified plyss2 lysins and uses thereof

Publications (2)

Publication Number Publication Date
JP2021513865A JP2021513865A (ja) 2021-06-03
JP2021513865A5 true JP2021513865A5 (enExample) 2022-02-09

Family

ID=67687985

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020544642A Pending JP2021513865A (ja) 2018-02-26 2019-02-26 修飾PlySs2溶解素及びその使用

Country Status (12)

Country Link
US (1) US20210032294A1 (enExample)
EP (1) EP3758738A4 (enExample)
JP (1) JP2021513865A (enExample)
KR (1) KR20200124724A (enExample)
CN (1) CN112118861A (enExample)
AU (1) AU2019224160A1 (enExample)
BR (1) BR112020017219A2 (enExample)
CA (1) CA3092109A1 (enExample)
IL (1) IL276807A (enExample)
MX (1) MX2020008860A (enExample)
RU (1) RU2020128276A (enExample)
WO (1) WO2019165454A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3980049A4 (en) * 2019-04-11 2023-07-19 Contrafect Corporation METHOD OF TREATMENT AND PREVENTION OF BONE AND JOINT INFECTIONS
WO2021236636A1 (en) * 2020-05-19 2021-11-25 Contrafect Corporation MODIFIED PlySs2 LYSINS AND ANTIBIOTIC COMBINATIONS FOR USE AGAINST GRAM-POSITIVE BACTERIA
WO2023049747A1 (en) * 2021-09-22 2023-03-30 Elanco Us Inc. Streptococcus suis lytic enzyme compositions and methods of use thereof
WO2023081691A1 (en) * 2021-11-04 2023-05-11 Contrafect Corporation Method of treating and preventing bone and joint infections
CN115851689A (zh) * 2022-08-09 2023-03-28 中南民族大学 一种嵌合裂解酶PlySs2E-V12C及其应用、重组质粒和重组菌株

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2833409A1 (en) * 2011-04-21 2012-10-26 The Rockefeller University Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria
CN103703127A (zh) * 2011-05-04 2014-04-02 迈克瑞欧斯人体健康有限公司 一种多肽
KR20210121313A (ko) * 2012-05-09 2021-10-07 콘트라펙트 코포레이션 그람 양성 박테리아에 대한 박테리오파지 리신과 항생제의 병용물
KR20200023521A (ko) * 2012-05-09 2020-03-04 콘트라펙트 코포레이션 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료
CN104073478A (zh) * 2014-06-13 2014-10-01 上海交通大学 杀灭革兰氏阳性菌的酶抗生素及其制备、用途
CN104211781A (zh) * 2014-09-04 2014-12-17 北京纳百景弈生物科技有限公司 金黄色葡萄球菌裂解蛋白的制备方法及其应用
KR20190004799A (ko) * 2016-05-12 2019-01-14 콘트라펙트 코포레이션 항균 폴리펩티드의 최소 억제 농도를 평가 및 탐지하기 위한 배지미량희석법

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