JP2021512926A5 - - Google Patents
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- Publication number
- JP2021512926A5 JP2021512926A5 JP2020542907A JP2020542907A JP2021512926A5 JP 2021512926 A5 JP2021512926 A5 JP 2021512926A5 JP 2020542907 A JP2020542907 A JP 2020542907A JP 2020542907 A JP2020542907 A JP 2020542907A JP 2021512926 A5 JP2021512926 A5 JP 2021512926A5
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- JP
- Japan
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- free acid
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- under suitable
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862628580P | 2018-02-09 | 2018-02-09 | |
| US62/628,580 | 2018-02-09 | ||
| PCT/US2019/017448 WO2019157426A1 (en) | 2018-02-09 | 2019-02-11 | Synthesis of 4-chlorokynurenines and intermediates |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021512926A JP2021512926A (ja) | 2021-05-20 |
| JPWO2019157426A5 JPWO2019157426A5 (https=) | 2022-02-22 |
| JP2021512926A5 true JP2021512926A5 (https=) | 2022-02-22 |
| JP7431163B2 JP7431163B2 (ja) | 2024-02-14 |
Family
ID=67548039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542907A Active JP7431163B2 (ja) | 2018-02-09 | 2019-02-11 | ４－クロロキヌレニンおよび中間体の合成 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11427530B2 (https=) |
| EP (1) | EP3749638B1 (https=) |
| JP (1) | JP7431163B2 (https=) |
| CN (2) | CN112236412B (https=) |
| CA (1) | CA3127220C (https=) |
| WO (1) | WO2019157426A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112236412B (zh) * | 2018-02-09 | 2024-01-30 | 维斯塔津治疗公司 | 4-氯代犬尿氨酸及中间体的合成 |
| WO2022082100A1 (en) * | 2020-10-16 | 2022-04-21 | Vistagen Therapeutics, Inc. | Cocrystals of l-4-chlorokynurenine, compositions and therapeutic uses thereof |
| CN118434750A (zh) * | 2021-12-23 | 2024-08-02 | 新魁特株式会社 | 有机锌化合物以及有机锌化合物的制造方法 |
| WO2023234187A1 (ja) * | 2022-05-31 | 2023-12-07 | シンクレスト株式会社 | 有機銅化合物の製造方法 |
| US20240368190A1 (en) * | 2023-04-14 | 2024-11-07 | Revolution Medicines, Inc. | Synthesis of ras inhibitors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU643365B2 (en) | 1991-02-28 | 1993-11-11 | Aventisub Ii Inc. | NMDA antagonists |
| US5484814A (en) | 1991-02-28 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| GB9618349D0 (en) | 1996-09-03 | 1996-10-16 | Pharmacia Spa | N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity |
| JP2001517246A (ja) * | 1997-06-23 | 2001-10-02 | 田辺製薬株式会社 | α▲下４▼β▲下１▼媒介細胞接着の阻止剤 |
| CN1309702C (zh) * | 2005-10-28 | 2007-04-11 | 中国科学院上海有机化学研究所 | 犬尿氨酸酶的特异性抑制剂l－邻甲氧基苯甲酰基丙氨酸的合成方法 |
| EP4385563A3 (en) | 2013-01-22 | 2024-08-21 | Vistagen Therapeutics, Inc. | Dosage forms and therapeutic uses l-4-chlorokynurenine |
| US20160031800A1 (en) * | 2013-03-14 | 2016-02-04 | Vistagen Therapeutics, Inc. | Synthesis of chiral kynurenine compounds and intermediates |
| CN107417558A (zh) * | 2013-03-14 | 2017-12-01 | 维斯塔津治疗公司 | 用于合成手性犬尿氨酸化合物的方法 |
| US9666192B2 (en) | 2015-05-26 | 2017-05-30 | Nuance Communications, Inc. | Methods and apparatus for reducing latency in speech recognition applications |
| WO2017044516A1 (en) * | 2015-09-08 | 2017-03-16 | Cephalon, Inc. | Prodrugs of chlorokynurenines |
| KR102021276B1 (ko) | 2015-10-15 | 2019-09-16 | 엑손모빌 업스트림 리서치 캄파니 | 진폭 보존을 갖는 fwi 모델 도메인 각도 스택들 |
| US20180305298A1 (en) * | 2015-10-16 | 2018-10-25 | Auspex Pharmaceuticals, Inc. | Deuterated chlorokynurenines for the treatment of neuropsychiatric disorders |
| CN107129444B (zh) * | 2016-02-29 | 2018-08-31 | 尚科生物医药（上海）有限公司 | (s)-2-叔丁氧羰基氨基-3-(4-氨甲酰基-2,6-二甲基苯基)丙酸制备方法 |
| CN112236412B (zh) * | 2018-02-09 | 2024-01-30 | 维斯塔津治疗公司 | 4-氯代犬尿氨酸及中间体的合成 |
-
2019
- 2019-02-11 CN CN201980021535.8A patent/CN112236412B/zh active Active
- 2019-02-11 US US16/967,627 patent/US11427530B2/en active Active
- 2019-02-11 EP EP19750605.8A patent/EP3749638B1/en active Active
- 2019-02-11 WO PCT/US2019/017448 patent/WO2019157426A1/en not_active Ceased
- 2019-02-11 JP JP2020542907A patent/JP7431163B2/ja active Active
- 2019-02-11 CN CN202410094204.XA patent/CN118026866A/zh active Pending
- 2019-02-11 CA CA3127220A patent/CA3127220C/en active Active
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