JP2021512873A5 - - Google Patents
Info
- Publication number
- JP2021512873A5 JP2021512873A5 JP2020542093A JP2020542093A JP2021512873A5 JP 2021512873 A5 JP2021512873 A5 JP 2021512873A5 JP 2020542093 A JP2020542093 A JP 2020542093A JP 2020542093 A JP2020542093 A JP 2020542093A JP 2021512873 A5 JP2021512873 A5 JP 2021512873A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazole
- amino
- phenyl
- methylphenyl
- fluoro
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20180015170 | 2018-02-07 | ||
| KR10-2018-0015170 | 2018-02-07 | ||
| PCT/KR2019/001404 WO2019156439A1 (en) | 2018-02-07 | 2019-01-31 | Compounds for inhibiting tnik and medical uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021512873A JP2021512873A (ja) | 2021-05-20 |
| JP2021512873A5 true JP2021512873A5 (https=) | 2022-02-04 |
| JPWO2019156439A5 JPWO2019156439A5 (https=) | 2022-02-04 |
| JP7302794B2 JP7302794B2 (ja) | 2023-07-04 |
Family
ID=67548327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542093A Active JP7302794B2 (ja) | 2018-02-07 | 2019-01-31 | Ｔｎｉｋを阻害するための化合物及びその医学的使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11485711B2 (https=) |
| EP (2) | EP4477271A3 (https=) |
| JP (1) | JP7302794B2 (https=) |
| KR (1) | KR102725207B1 (https=) |
| CN (1) | CN111836801B (https=) |
| AU (1) | AU2019217094B2 (https=) |
| CA (1) | CA3090233A1 (https=) |
| WO (1) | WO2019156439A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102725207B1 (ko) | 2018-02-07 | 2024-11-01 | 한국화학연구원 | Tnik 저해용 화합물 및 이들의 의약 용도 |
| WO2019156438A1 (en) * | 2018-02-07 | 2019-08-15 | Korea Research Institute Of Chemical Technology | Hetero ring-fused phenyl compounds for inhibiting tnik and medical uses thereof |
| CN111718310B (zh) * | 2019-08-19 | 2021-06-11 | 中国药科大学 | 苯基取代的五元杂环类化合物及其制备方法、用途和药物组合物 |
| WO2022034587A1 (en) * | 2020-08-10 | 2022-02-17 | Tnik Therapeutics Ltd | Traf2- AND Nck-INTERACTING KINASE (TNIK) INHIBITORS AND USES THEREOF |
| CA3237812A1 (en) * | 2021-11-12 | 2023-05-19 | Biopolar Youtang (Guangdong) Pharmaceutical Co., Ltd. | Drak2 inhibitor, and preparation method therefor and use thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0248523B1 (en) * | 1986-05-07 | 1991-10-16 | FISONS plc | Pyrazoles |
| GB8611102D0 (en) * | 1986-05-07 | 1986-06-11 | Fisons Plc | Heterocyclic compounds |
| JP2004501083A (ja) | 2000-04-18 | 2004-01-15 | アゴーロン・ファーマシューティカルズ・インコーポレイテッド | プロテインキナーゼを阻害するためのピラゾール |
| MXPA06000933A (es) | 2003-07-25 | 2006-03-30 | Pfizer | Compuestos de aminopirazol y uso como inhibidores de chk1. |
| WO2009030890A1 (en) | 2007-09-03 | 2009-03-12 | University Court Of The University Of Dundee | Pyrimidine compounds for the treatment of cancer, septic shock and/or primary open angle glaucoma |
| US20100216795A1 (en) | 2008-12-01 | 2010-08-26 | Tesshi Yamada | Tnik inhibitor and the use |
| GB0903759D0 (en) | 2009-03-04 | 2009-04-15 | Medical Res Council | Compound |
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| KR101663277B1 (ko) * | 2015-03-30 | 2016-10-06 | 주식회사 녹십자 | TNIK, IKKε 및 TBK1 억제제로서의 피라졸계 유도체 및 이를 포함하는 약학적 조성물 |
| EP3302156B1 (en) | 2015-05-29 | 2020-07-01 | Nike Innovate C.V. | Article of footwear comprising motorized tensioning device |
| KR102725207B1 (ko) | 2018-02-07 | 2024-11-01 | 한국화학연구원 | Tnik 저해용 화합물 및 이들의 의약 용도 |
-
2019
- 2019-01-31 KR KR1020207024628A patent/KR102725207B1/ko active Active
- 2019-01-31 CA CA3090233A patent/CA3090233A1/en active Pending
- 2019-01-31 JP JP2020542093A patent/JP7302794B2/ja active Active
- 2019-01-31 CN CN201980016887.4A patent/CN111836801B/zh active Active
- 2019-01-31 WO PCT/KR2019/001404 patent/WO2019156439A1/en not_active Ceased
- 2019-01-31 EP EP24201292.0A patent/EP4477271A3/en active Pending
- 2019-01-31 AU AU2019217094A patent/AU2019217094B2/en active Active
- 2019-01-31 US US16/967,844 patent/US11485711B2/en active Active
- 2019-01-31 EP EP19751775.8A patent/EP3749648B1/en active Active
-
2022
- 2022-09-07 US US17/939,147 patent/US11767297B2/en active Active
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