JP2005521721A5 - - Google Patents
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- Publication number
- JP2005521721A5 JP2005521721A5 JP2003580271A JP2003580271A JP2005521721A5 JP 2005521721 A5 JP2005521721 A5 JP 2005521721A5 JP 2003580271 A JP2003580271 A JP 2003580271A JP 2003580271 A JP2003580271 A JP 2003580271A JP 2005521721 A5 JP2005521721 A5 JP 2005521721A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- amino
- diphenylethyl
- methyl
- propoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36842602P | 2002-03-27 | 2002-03-27 | |
| PCT/US2003/009278 WO2003082802A1 (en) | 2002-03-27 | 2003-03-26 | Acid and ester compounds and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235241A Division JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005521721A JP2005521721A (ja) | 2005-07-21 |
| JP2005521721A5 true JP2005521721A5 (https=) | 2006-05-18 |
Family
ID=28675490
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003580271A Withdrawn JP2005521721A (ja) | 2002-03-27 | 2003-03-26 | 酸およびエステル化合物ならびにその使用方法 |
| JP2009235241A Pending JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235241A Pending JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7560586B2 (https=) |
| EP (1) | EP1487776A4 (https=) |
| JP (2) | JP2005521721A (https=) |
| AU (1) | AU2003222083A1 (https=) |
| WO (1) | WO2003082802A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7247748B2 (en) | 2002-03-27 | 2007-07-24 | Smithkline Corporation | Amide compounds and methods of using the same |
| AU2003226094A1 (en) | 2002-03-27 | 2003-10-13 | Smithkline Beecham Corporation | Compounds and methods |
| ATE453389T1 (de) | 2002-03-27 | 2010-01-15 | Smithkline Beecham Corp | Bestimmte pharmazeutisch wertvolle substituierte aminoalkyl-heterocyclen |
| US20060189693A1 (en) * | 2003-07-22 | 2006-08-24 | Barone Frank C | Methods of treatment with lxr agonists |
| AU2005211807C1 (en) * | 2004-02-11 | 2009-07-16 | Irm Llc | Compounds and compositions as LXR modulators |
| FR2869904B1 (fr) | 2004-05-07 | 2006-07-28 | Fournier S A Sa Lab | Modulateurs des recepteurs lxr |
| US7989179B2 (en) * | 2005-06-28 | 2011-08-02 | Daiichi Sankyo Company, Limited | LXR ligand testing method |
| US8993628B2 (en) * | 2007-02-23 | 2015-03-31 | City Of Hope | Synthetic ligands selective for LXRβ over LXRα, identification and methods of use thereof |
| US20130274212A1 (en) | 2010-09-07 | 2013-10-17 | Snu R&Db Foundation | Sesterterpene Compounds and Use Thereof |
| EP3626309B1 (en) | 2012-08-13 | 2023-03-08 | The Rockefeller University | Lxrbeta agonist for the treatment of cancer |
| US10669296B2 (en) | 2014-01-10 | 2020-06-02 | Rgenix, Inc. | LXR agonists and uses thereof |
| CA3010883A1 (en) | 2016-01-11 | 2017-07-20 | The Rockefeller University | Methods for the treatment of myeloid derived suppressor cells related disorders |
| CN110494415A (zh) | 2017-03-03 | 2019-11-22 | 睿治尼斯公司 | 具有改善的稳定性的制剂 |
| TWI683808B (zh) | 2017-07-18 | 2020-02-01 | 德商菲尼克斯 Ｆｘｒ有限責任公司 | 含有胺或(硫)醯胺之lxr調節劑 |
| EP3713575A4 (en) * | 2017-11-21 | 2021-08-25 | Rgenix, Inc. | POLYMORPHS AND THEIR USES |
| TWI748194B (zh) | 2018-06-28 | 2021-12-01 | 德商菲尼克斯 Ｆｘｒ有限責任公司 | 含有雙環核心部分之新穎lxr調節劑 |
| CN114126618A (zh) | 2019-07-15 | 2022-03-01 | 诺华股份有限公司 | 用肝脏x受体激动剂治疗睑板腺功能障碍的方法 |
| HUE067466T2 (hu) | 2019-12-13 | 2024-10-28 | Inspirna Inc | Fémsók és alkalmazásuk |
| CN112079732B (zh) * | 2020-09-22 | 2021-10-08 | 湖南大学 | 一种4-烃基仲胺基-2-丁醇类化合物的合成路线 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US72868A (en) * | 1867-12-31 | Lewis leigh | ||
| US699659A (en) * | 1900-08-10 | 1902-05-13 | Michael R Colvin | Gas stop-cock. |
| ES444144A1 (es) * | 1975-01-14 | 1977-08-16 | Hoechst Ag | Un procedimiento para la preparacion de un acido 6,11-dihi- dro-11-oxo-dibenz (b, e) oxepin-alcanoico. |
| DE3889545T2 (de) | 1987-10-20 | 1994-10-13 | Otsuka Pharma Co Ltd | Phenylcarbonsäure-abkömmlinge. |
| US6499762B1 (en) * | 1995-06-05 | 2002-12-31 | Adorno/Rogers Technology, Inc. | Frame support apparatus and coupling device for use with an ambulatory system and method of fabrication thereof |
| JP3676074B2 (ja) * | 1997-03-14 | 2005-07-27 | Ｔｄｋ株式会社 | ホットメルト材およびラミネート体とその製造方法 |
| US20030153541A1 (en) | 1997-10-31 | 2003-08-14 | Robert Dudley | Novel anticholesterol compositions and method for using same |
| DE19826414A1 (de) * | 1998-06-16 | 1999-12-23 | Coronet Werke Gmbh | Verfahren zum Verbinden, Markieren und struktuellem Verändern von Monofilen |
| FR2811973A1 (fr) * | 2000-07-18 | 2002-01-25 | Windmoeller & Hoelscher | Agencement de grue pour le transport de rouleaux de bandes |
| JP2004509161A (ja) * | 2000-09-18 | 2004-03-25 | グラクソ グループ リミテッド | Ｌｘｒのアゴニストとして有用な置換アミノプロポキシアリール誘導体 |
| US7470659B2 (en) | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| JP2005511713A (ja) | 2001-12-07 | 2005-04-28 | ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 加齢性黄斑変性についての処置 |
| US20030229062A1 (en) | 2001-12-07 | 2003-12-11 | The Regents Of The University Of California | Treatments for age-related macular degeneration (AMD) |
| US20050171084A1 (en) | 2002-03-27 | 2005-08-04 | Cairns William J. | Methods of treatment with lxr modulators |
| ATE453389T1 (de) | 2002-03-27 | 2010-01-15 | Smithkline Beecham Corp | Bestimmte pharmazeutisch wertvolle substituierte aminoalkyl-heterocyclen |
| AU2003226094A1 (en) | 2002-03-27 | 2003-10-13 | Smithkline Beecham Corporation | Compounds and methods |
| US7247748B2 (en) | 2002-03-27 | 2007-07-24 | Smithkline Corporation | Amide compounds and methods of using the same |
| WO2004058175A2 (en) | 2002-12-23 | 2004-07-15 | Irm Llc | Novel use of liver x receptor agonists |
| GB0230177D0 (en) | 2002-12-24 | 2003-02-05 | Karobio Ab | LXR beta crystal |
| EP1635832A2 (en) | 2003-06-06 | 2006-03-22 | Merck & Co., Inc. | Combination therapy for the treatment of diabetes |
| WO2004110368A2 (en) | 2003-06-06 | 2004-12-23 | Merck & Co., Inc. | Combination therapy for the treatment of hypertension |
| US20060189693A1 (en) | 2003-07-22 | 2006-08-24 | Barone Frank C | Methods of treatment with lxr agonists |
| EP1653938A2 (en) | 2003-07-28 | 2006-05-10 | Glaxo Group Limited | Methods of treatment of inflammatory bowel disease with lxr agonists |
| WO2005055998A1 (en) | 2003-12-04 | 2005-06-23 | Smithkline Beecham Corporation | Methods of treatment with lxr agonists |
| RU2006124843A (ru) | 2003-12-12 | 2008-01-20 | Уайт (Us) | Хинолины, пригодные для лечения сердечно-сосудистого заболевания |
| EP1758651A2 (en) | 2004-06-24 | 2007-03-07 | Galapagos N.V. | Lxr agonists to promote bone homeostasis |
| US20080255111A1 (en) | 2004-07-02 | 2008-10-16 | Sankyo Company Limited | Tissue Factor Production Inhibitor |
-
2003
- 2003-03-26 EP EP03718068A patent/EP1487776A4/en not_active Withdrawn
- 2003-03-26 WO PCT/US2003/009278 patent/WO2003082802A1/en not_active Ceased
- 2003-03-26 JP JP2003580271A patent/JP2005521721A/ja not_active Withdrawn
- 2003-03-26 US US10/508,893 patent/US7560586B2/en not_active Expired - Lifetime
- 2003-03-26 AU AU2003222083A patent/AU2003222083A1/en not_active Abandoned
-
2009
- 2009-10-09 JP JP2009235241A patent/JP2010047582A/ja active Pending
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