JP2005521721A5 - - Google Patents
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- Publication number
- JP2005521721A5 JP2005521721A5 JP2003580271A JP2003580271A JP2005521721A5 JP 2005521721 A5 JP2005521721 A5 JP 2005521721A5 JP 2003580271 A JP2003580271 A JP 2003580271A JP 2003580271 A JP2003580271 A JP 2003580271A JP 2005521721 A5 JP2005521721 A5 JP 2005521721A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- amino
- diphenylethyl
- methyl
- propoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36842602P | 2002-03-27 | 2002-03-27 | |
| PCT/US2003/009278 WO2003082802A1 (en) | 2002-03-27 | 2003-03-26 | Acid and ester compounds and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235241A Division JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005521721A JP2005521721A (ja) | 2005-07-21 |
| JP2005521721A5 true JP2005521721A5 (https=) | 2006-05-18 |
Family
ID=28675490
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003580271A Withdrawn JP2005521721A (ja) | 2002-03-27 | 2003-03-26 | 酸およびエステル化合物ならびにその使用方法 |
| JP2009235241A Pending JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235241A Pending JP2010047582A (ja) | 2002-03-27 | 2009-10-09 | 酸およびエステル化合物ならびにその使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7560586B2 (https=) |
| EP (1) | EP1487776A4 (https=) |
| JP (2) | JP2005521721A (https=) |
| AU (1) | AU2003222083A1 (https=) |
| WO (1) | WO2003082802A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003220558A1 (en) | 2002-03-27 | 2004-06-03 | Smithkline Beecham Corporation | Amide compounds and methods of using the same |
| EP1490047B1 (en) | 2002-03-27 | 2009-12-30 | SmithKline Beecham Corporation | Certain pharmaceutically useful substituted aminoalkyl heterocycles |
| EP1575495A4 (en) * | 2002-03-27 | 2009-12-02 | Smithkline Beecham Corp | COMPOUNDS AND METHODS |
| US20060189693A1 (en) * | 2003-07-22 | 2006-08-24 | Barone Frank C | Methods of treatment with lxr agonists |
| WO2005077122A2 (en) * | 2004-02-11 | 2005-08-25 | Irm Llc | Compounds and compositions as lxr modulators |
| FR2869904B1 (fr) | 2004-05-07 | 2006-07-28 | Fournier S A Sa Lab | Modulateurs des recepteurs lxr |
| US7989179B2 (en) * | 2005-06-28 | 2011-08-02 | Daiichi Sankyo Company, Limited | LXR ligand testing method |
| US8993628B2 (en) * | 2007-02-23 | 2015-03-31 | City Of Hope | Synthetic ligands selective for LXRβ over LXRα, identification and methods of use thereof |
| WO2012033353A2 (ko) | 2010-09-07 | 2012-03-15 | 서울대학교 산학협력단 | 세스터터핀 화합물 및 이들 물질의 용도 |
| AU2013302861A1 (en) * | 2012-08-13 | 2015-03-05 | The Rockefeller University | Treatment and diagnosis of melanoma |
| WO2015106164A1 (en) * | 2014-01-10 | 2015-07-16 | Rgenix, Inc. | Lxr agonists and uses thereof |
| EP3402477A4 (en) | 2016-01-11 | 2019-08-21 | The Rockefeller University | METHOD FOR THE TREATMENT OF DISEASES RELATED TO MYELOID-DERIVED SUPPRESSOR CELLS |
| EP3589280B1 (en) * | 2017-03-03 | 2024-02-07 | Inspirna, Inc. | Formulations with improved stability |
| TWI683808B (zh) | 2017-07-18 | 2020-02-01 | 德商菲尼克斯 Ｆｘｒ有限責任公司 | 含有胺或(硫)醯胺之lxr調節劑 |
| CA3078981A1 (en) | 2017-11-21 | 2019-05-31 | Rgenix, Inc. | Polymorphs and uses thereof |
| TWI748194B (zh) | 2018-06-28 | 2021-12-01 | 德商菲尼克斯 Ｆｘｒ有限責任公司 | 含有雙環核心部分之新穎lxr調節劑 |
| EP3999055A1 (en) | 2019-07-15 | 2022-05-25 | Novartis AG | Methods for treating meibomian gland dysfunction with liver x receptor agonists |
| TWI888447B (zh) | 2019-12-13 | 2025-07-01 | 美商因思博納公司 | 金屬鹽及其用途 |
| CN112079732B (zh) * | 2020-09-22 | 2021-10-08 | 湖南大学 | 一种4-烃基仲胺基-2-丁醇类化合物的合成路线 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US72868A (en) * | 1867-12-31 | Lewis leigh | ||
| US699659A (en) * | 1900-08-10 | 1902-05-13 | Michael R Colvin | Gas stop-cock. |
| ES444144A1 (es) | 1975-01-14 | 1977-08-16 | Hoechst Ag | Un procedimiento para la preparacion de un acido 6,11-dihi- dro-11-oxo-dibenz (b, e) oxepin-alcanoico. |
| DE3889545T2 (de) * | 1987-10-20 | 1994-10-13 | Otsuka Pharma Co Ltd | Phenylcarbonsäure-abkömmlinge. |
| US6499762B1 (en) * | 1995-06-05 | 2002-12-31 | Adorno/Rogers Technology, Inc. | Frame support apparatus and coupling device for use with an ambulatory system and method of fabrication thereof |
| JP3676074B2 (ja) * | 1997-03-14 | 2005-07-27 | Ｔｄｋ株式会社 | ホットメルト材およびラミネート体とその製造方法 |
| US20030153541A1 (en) * | 1997-10-31 | 2003-08-14 | Robert Dudley | Novel anticholesterol compositions and method for using same |
| DE19826414A1 (de) * | 1998-06-16 | 1999-12-23 | Coronet Werke Gmbh | Verfahren zum Verbinden, Markieren und struktuellem Verändern von Monofilen |
| FR2811973A1 (fr) * | 2000-07-18 | 2002-01-25 | Windmoeller & Hoelscher | Agencement de grue pour le transport de rouleaux de bandes |
| WO2002024632A2 (en) * | 2000-09-18 | 2002-03-28 | Glaxo Group Limited | Substituted aminopropoxyaryl derivatives useful as agonists for lxr |
| US20030229062A1 (en) * | 2001-12-07 | 2003-12-11 | The Regents Of The University Of California | Treatments for age-related macular degeneration (AMD) |
| WO2003049685A2 (en) * | 2001-12-07 | 2003-06-19 | The Regents Of The University Of California | Treatment for age-related macular degeneration |
| US7470659B2 (en) * | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| AU2003220558A1 (en) * | 2002-03-27 | 2004-06-03 | Smithkline Beecham Corporation | Amide compounds and methods of using the same |
| US20050171084A1 (en) * | 2002-03-27 | 2005-08-04 | Cairns William J. | Methods of treatment with lxr modulators |
| EP1575495A4 (en) * | 2002-03-27 | 2009-12-02 | Smithkline Beecham Corp | COMPOUNDS AND METHODS |
| EP1490047B1 (en) | 2002-03-27 | 2009-12-30 | SmithKline Beecham Corporation | Certain pharmaceutically useful substituted aminoalkyl heterocycles |
| WO2004058175A2 (en) * | 2002-12-23 | 2004-07-15 | Irm Llc | Novel use of liver x receptor agonists |
| GB0230177D0 (en) | 2002-12-24 | 2003-02-05 | Karobio Ab | LXR beta crystal |
| EP1635832A2 (en) | 2003-06-06 | 2006-03-22 | Merck & Co., Inc. | Combination therapy for the treatment of diabetes |
| EP1635773A2 (en) | 2003-06-06 | 2006-03-22 | Merck & Co., Inc. (a New Jersey corp.) | Combination therapy for the treatment of hypertension |
| US20060189693A1 (en) | 2003-07-22 | 2006-08-24 | Barone Frank C | Methods of treatment with lxr agonists |
| JP2007500158A (ja) | 2003-07-28 | 2007-01-11 | グラクソ グループ リミテッド | Ｌｘｒアゴニストを用いる炎症性腸疾患の治療方法 |
| WO2005055998A1 (en) | 2003-12-04 | 2005-06-23 | Smithkline Beecham Corporation | Methods of treatment with lxr agonists |
| AU2004298486A1 (en) * | 2003-12-12 | 2005-06-30 | Wyeth | Quinolines useful in treating cardiovascular disease |
| US20060020036A1 (en) | 2004-06-24 | 2006-01-26 | Luc Van Rompaey | Methods and compositions to promote bone homestasis |
| WO2006004030A1 (ja) | 2004-07-02 | 2006-01-12 | Sankyo Company, Limited | 組織因子産生抑制剤 |
-
2003
- 2003-03-26 US US10/508,893 patent/US7560586B2/en not_active Expired - Lifetime
- 2003-03-26 WO PCT/US2003/009278 patent/WO2003082802A1/en not_active Ceased
- 2003-03-26 AU AU2003222083A patent/AU2003222083A1/en not_active Abandoned
- 2003-03-26 EP EP03718068A patent/EP1487776A4/en not_active Withdrawn
- 2003-03-26 JP JP2003580271A patent/JP2005521721A/ja not_active Withdrawn
-
2009
- 2009-10-09 JP JP2009235241A patent/JP2010047582A/ja active Pending
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