JP2021512744A - 駆動サブアセンブリを有する薬物送達デバイス - Google Patents
駆動サブアセンブリを有する薬物送達デバイス Download PDFInfo
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- JP2021512744A JP2021512744A JP2020560544A JP2020560544A JP2021512744A JP 2021512744 A JP2021512744 A JP 2021512744A JP 2020560544 A JP2020560544 A JP 2020560544A JP 2020560544 A JP2020560544 A JP 2020560544A JP 2021512744 A JP2021512744 A JP 2021512744A
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Abstract
【選択図】図9
Description
− ハウジングまたはその一部、特に近位領域、およびプランジャを含む駆動サブアセンブリであって、プランジャは、プランジャの前進が防止されるロック位置と、プランジャが前進可能な解放位置との間で回転するように適用され、少なくとも1つの拘束構成要素が設けられ、ロック位置から解放位置へのプランジャの回転を拘束する、薬物送達デバイス用の駆動サブアセンブリと、
− ハウジングに連結されたシリンジおよびスリーブを受け取って、プランジャを解放するためのハウジングに対するスリーブの動きを可能にするように適用されたハウジングの遠位領域を含む制御サブアセンブリとを含む。
− プランジャ40上の第1のプランジャボス40.1と、
− プランジャ40上の第2のプランジャボス40.2と、
− プランジャ40上の傾斜プランジャリブ40.3と、
− 第1のプランジャボス40.1と相互作用するように適用された近位領域21内のプロファイルスロット21.1と、
− スリーブ13上のスリーブリブ13.1とを含み、スリーブリブ13.1は、傾斜プランジャリブ40.3と相互作用するように適用された近位面13.2と、遠位面13.3と、第2のプランジャボス40.2と相互作用するように適用された長手方向面13.4とを含む。
10.1 駆動サブアセンブリ
11 ハウジング
11a 窓
12 キャップアセンブリ
13 スリーブ
13.1 スリーブリブ
13.2 近位面
13.3 遠位面
13.4 長手方向面
17 針
20 遠位領域
21 近位領域
21.1 プロファイルスロット
21.2 第1の傾斜面
21.3 壁
21.4 第2の傾斜面
21.5 ハウジング突起
21.6 ハウジングビーム
21.7 固定端
21.8 自由端
21.9 遠位突起
21.10 面取り部
21.11 ハウジング突起
21.12 縁部
21.13 横断突起
21.14 近位壁
21.15 くぼみ
21.16 斜面
21.17 斜面
22 ボタン
23 ピストン
24 シリンジ
25 プランジャ解放機構
25.1 ハウジング突起
30 駆動ばね
40 プランジャ
40.1 第1のプランジャボス
40.2 第2のプランジャボス
40.3 傾斜プランジャリブ
40.4 プランジャ突起
40.5 面取り部
40.6 追加のプランジャボス
40.7 凹部
40.8 縁部
40.9 近位ボス
D 遠位端、遠位方向
P 近位端、近位方向
R1 第1の回転方向
X 長手方向軸
Claims (15)
- 薬物送達デバイス(10)であって:
ハウジング(11)およびプランジャ(40)を含む駆動サブアセンブリ(10.1)であって、プランジャ(40)は、プランジャ(40)の前進が防止されるロック位置と、プランジャ(40)が前進可能な解放位置との間で回転するように適用され、少なくとも1つの拘束構成要素が設けられ、好ましくはプライミング工程中、ロック位置から解放位置へのプランジャ(40)の回転を拘束する、駆動サブアセンブリと、
ハウジング(11)に連結されたシリンジ(24)およびスリーブ(13)を受け取って、プランジャ(40)を解放するためのハウジング(11)に対するスリーブ(13)の動きを可能にするように適用されたハウジング(11)の遠位領域(20)を含む制御サブアセンブリとを含み、
ここで、薬物送達デバイス(10)は、薬剤を収容するシリンジ(24)を含むことができる、前記薬物送達デバイス。 - 少なくとも1つの拘束構成要素は、ハウジング(11)上の変形可能なハウジング突起(21.5、21.11)と、プランジャ(40)上のプランジャボス(40.1、40.6)または縁部(40.8)とを含み、プランジャボス(40.1、40.6)または縁部(40.8)は、プランジャ(40)がロック位置から解放位置へ回転したとき、ハウジング突起(21.5、21.11)に当接するように適用され、プランジャが解放位置の方へさらに回転したとき、ハウジング突起(21.5、21.11)を変形させるように適用され、ハウジング突起(21.5、21.11)は、径方向内方へまたは遠位方向(D)に突出することができ、プランジャボス(40.1、40.6)は、弾性または塑性変形可能とすることができる、請求項1に記載の薬物送達デバイス(10)。
- プランジャボス(40.1、40.6)は、ハウジング突起(21.5)に当接するように適用された径方向のプランジャ突起(40.4)を含む、請求項2に記載の薬物送達デバイス(10)。
- プランジャ突起(40.4)またはプランジャボス(40.1、40.6)は、プランジャ(40)が解放位置からロック位置へ回転したとき、ハウジング突起(21.5)に係合するように適用された面取り部(40.5)を含む、請求項2または3に記載の薬物送達デバイス(10)。
- 縁部(40.8)は、プランジャ(40)の近位面内の凹部(40.7)上に配置される、請求項2〜4のいずれか1項に記載の薬物送達デバイス(10)。
- 少なくとも1つの拘束構成要素は、横断構成要素(21.6、21.13)と、プランジャ(40)上のプランジャボス(40.1)とを含み、該プランジャボスは、ロック位置にあるとき、横断構成要素(21.6、21.13)に当接し、プランジャ(40)の近位への動きを拘束するように近位方向(P)に動くように適用される、請求項1に記載の薬物送達デバイス(10)。
- 横断構成要素(21.6)は、ハウジング(11)に連結された固定端(21.7)と、自由端(21.8)とを含むハウジングビーム(21.6)であり、自由端(21.8)は、プランジャ(40)がロック位置から解放位置へ回転したとき、プランジャボス(40.1)に当接するように適用された遠位突起(21.9)を含み、ハウジングビーム(21.6)は、弾性または塑性変形可能とすることができる、請求項6に記載の薬物送達デバイス(10)。
- 遠位突起(21.9)は、プランジャ(40)が解放位置からロック位置へ回転したとき、プランジャボス(40.1)に係合するように適用された面取り部(40.5)を含む、請求項7に記載の薬物送達デバイス(10)。
- 横断構成要素(21.6、21.13)は、プランジャボス(40.1)に係合するための少なくとも1つの丸いまたは面取り縁部を含む、請求項6〜8のいずれか1項に記載の薬物送達デバイス(10)。
- 横断構成要素(21.6、21.13)は、プランジャ(40)がロック位置から外れたとき、プランジャボス(40.1)と横断構成要素(21.6、21.13)との間に軸方向の隙間を可能にするように軸方向に位置する、請求項6〜9のいずれか1項に記載の薬物送達デバイス(10)。
- 少なくとも1つの拘束構成要素は、プランジャ(40)上のプランジャボス(40.1)と、ハウジング(11)内のくぼみ(21.5)とを含み、プランジャボス(40.1)は、ロック位置から解放位置へのプランジャ(40)の回転を拘束するためにくぼみ(21.5)内に受け入れられるように適用された近位方向(P)に突出する近位ボス(40.9)を有する、請求項1に記載の薬物送達デバイス(10)。
- くぼみ(21.5)は、近位ボス(40.9)をくぼみ(21.5)内へ案内し、プランジャ(40)をロック位置へ回転させるように適用された斜面(21.16)を含む、請求項11に記載の薬物送達デバイス(10)。
- ハウジング(11)上に斜面(21.17)が設けられ、斜面(21.17)は、プランジャ(40)をハウジング(11)内へ組み立てている間はプランジャ(40)に係合し、プランジャ(40)がハウジング(11)に対して近位方向(P)に動いたときはプランジャ(40)をロック位置へ回転させるように適用される、請求項1〜12のいずれか1項に記載の薬物送達デバイス(10)。
- プランジャ(40)をハウジング(11)に対して遠位方向(D)に付勢するように適用された駆動ばね(30)をさらに含む、請求項1〜13のいずれか1項に記載の薬物送達デバイス(10)。
- スリーブ(13)は、プランジャボス(40.1、40.2、40.6)と相互作用する長手方向面(13.4)を有するスリーブリブ(13.1)を含み、好ましくは、スリーブ(13)が伸長位置から後退位置へ動いているとき、プランジャボス(40.1、40.2、40.6)が、スリーブ(13)に対して遠位方向(D)に動き、スリーブリブ(13.1)の長手方向面(13.4)に沿って案内された後、プランジャボス(40.1、40.2、40.6)がスリーブリブ(13.1)を越えて遠位に動き、したがってプランジャ(40)が第1の回転方向(R1)に回転することが防止されなくなる、請求項1〜14のいずれか1項に記載の薬物送達デバイス(10)。
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