JP2021511324A5 - - Google Patents
Info
- Publication number
- JP2021511324A5 JP2021511324A5 JP2020539784A JP2020539784A JP2021511324A5 JP 2021511324 A5 JP2021511324 A5 JP 2021511324A5 JP 2020539784 A JP2020539784 A JP 2020539784A JP 2020539784 A JP2020539784 A JP 2020539784A JP 2021511324 A5 JP2021511324 A5 JP 2021511324A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- dihydro
- pyrrolidine
- fluoro
- trifluoromethylbenzyl
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2018/051278 | 2018-01-19 | ||
| EP2018051278 | 2018-01-19 | ||
| PCT/EP2019/051230 WO2019141803A1 (en) | 2018-01-19 | 2019-01-18 | C5a receptor modulators |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021511324A JP2021511324A (ja) | 2021-05-06 |
| JP2021511324A5 true JP2021511324A5 (https=) | 2022-01-21 |
| JPWO2019141803A5 JPWO2019141803A5 (https=) | 2022-01-21 |
| JP7281469B2 JP7281469B2 (ja) | 2023-05-25 |
Family
ID=65023914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020539784A Active JP7281469B2 (ja) | 2018-01-19 | 2019-01-18 | Ｃ５ａ受容体調節剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11739070B2 (https=) |
| EP (1) | EP3740476A1 (https=) |
| JP (1) | JP7281469B2 (https=) |
| CN (1) | CN111615513A (https=) |
| CA (1) | CA3087886A1 (https=) |
| WO (1) | WO2019141803A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3737684B1 (en) | 2018-01-10 | 2022-11-16 | Idorsia Pharmaceuticals Ltd | 2,4,6,7-tetrahydro-pyrazolo[4,3-d]pyrimidin-5-one derivatives and related compounds as c5a receptor modulators for treating vasculitis and inflammatory diseases |
| US11685729B2 (en) | 2018-01-19 | 2023-06-27 | Idorsia Pharmaceuticals Ltd. | C5a receptor modulators |
| CA3087886A1 (en) | 2018-01-19 | 2019-07-25 | Idorsia Pharmaceuticals Ltd | C5a receptor modulators |
| JP7458987B2 (ja) * | 2018-09-13 | 2024-04-01 | キッセイ薬品工業株式会社 | イミダゾピリジノン化合物 |
| JP7654426B2 (ja) * | 2020-03-12 | 2025-04-01 | キッセイ薬品工業株式会社 | イミダゾピリジノン化合物の製造方法 |
| US11919879B2 (en) | 2021-06-16 | 2024-03-05 | Celgene Corporation | Carboxylic acid containing azetidinyl compounds for the treatment of neurodegenerative diseases |
| WO2026013291A1 (en) * | 2024-07-11 | 2026-01-15 | University Of Dundee | Inhibitors of rna methyltransferase |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51125286A (en) * | 1975-02-14 | 1976-11-01 | Yoshitomi Pharmaceut Ind Ltd | A process for preparing novel 3- substituted n-benzylpyrrolidine deriv atives |
| FR2722190B1 (fr) | 1994-07-05 | 1996-10-04 | Sanofi Sa | Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant |
| EA200000683A1 (ru) | 1998-01-19 | 2000-12-25 | Пфайзер Инк. | Производные ряда 4-(2-кето-1-бензимидазолинил)пиперидина в качестве агонистов orl1-рецептора |
| US6645971B1 (en) | 1998-10-16 | 2003-11-11 | Sumitomo Pharmaceuticals Company Limited | Quinazolinone derivatives |
| NZ510760A (en) | 1998-10-23 | 2003-08-29 | F | Bicyclic nitrogen heterocycles |
| WO2001005770A1 (en) | 1999-07-21 | 2001-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazolone derivatives and their use as phosphodiesterase inhibitors |
| US6476050B2 (en) | 2000-03-14 | 2002-11-05 | Sepracor, Inc. | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
| WO2003037890A2 (en) | 2001-11-01 | 2003-05-08 | Icagen, Inc. | Piperidines |
| NZ535764A (en) | 2002-04-18 | 2007-10-26 | Schering Corp | 1-(4-piperidinyl) benzimidazolones as histamine H3 antagonists |
| AU2004308712A1 (en) | 2003-12-23 | 2005-07-14 | Tibotec Pharmaceuticals Ltd. | Self-microemulsifying drug delivery systems of a HIV protease inhibitor |
| WO2008147697A1 (en) | 2007-05-22 | 2008-12-04 | Boehringer Ingelheim International Gmbh | Benzimidazolone chymase inhibitors |
| BR112012030711B1 (pt) * | 2010-05-31 | 2020-10-13 | Ono Pharmaceutical Co. Ltd | derivado de purinona |
| US20120143725A1 (en) | 2010-12-02 | 2012-06-07 | Vinimaya Inc. | Methods and systems for influencing search and shopping decisions in electronic procurement |
| GB201106814D0 (en) | 2011-04-21 | 2011-06-01 | Astex Therapeutics Ltd | New compounds |
| JP6417419B2 (ja) | 2013-09-04 | 2018-11-07 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | 免疫調節剤として有用な化合物 |
| HRP20181052T1 (hr) | 2013-09-06 | 2018-09-07 | Aurigene Discovery Technologies Limited | Derivati 1,2,4-oksadiazola kao imunomodulatori |
| WO2015044900A1 (en) | 2013-09-27 | 2015-04-02 | Aurigene Discovery Technologies Limited | Therapeutic immunomodulating compounds |
| EP3737684B1 (en) | 2018-01-10 | 2022-11-16 | Idorsia Pharmaceuticals Ltd | 2,4,6,7-tetrahydro-pyrazolo[4,3-d]pyrimidin-5-one derivatives and related compounds as c5a receptor modulators for treating vasculitis and inflammatory diseases |
| CA3087886A1 (en) | 2018-01-19 | 2019-07-25 | Idorsia Pharmaceuticals Ltd | C5a receptor modulators |
| US11685729B2 (en) | 2018-01-19 | 2023-06-27 | Idorsia Pharmaceuticals Ltd. | C5a receptor modulators |
-
2019
- 2019-01-18 CA CA3087886A patent/CA3087886A1/en active Pending
- 2019-01-18 CN CN201980008986.8A patent/CN111615513A/zh active Pending
- 2019-01-18 US US16/963,101 patent/US11739070B2/en active Active
- 2019-01-18 EP EP19700612.5A patent/EP3740476A1/en not_active Withdrawn
- 2019-01-18 WO PCT/EP2019/051230 patent/WO2019141803A1/en not_active Ceased
- 2019-01-18 JP JP2020539784A patent/JP7281469B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021511324A5 (https=) | ||
| JP2022189853A5 (https=) | ||
| JP2018520105A5 (https=) | ||
| EP2655340B1 (en) | Bi-heteroaryl compounds as vps34 inhibitors | |
| RU2481333C2 (ru) | Производные 1,1,1-трифтор-2-гидрокси-3-фенилпропана | |
| US20180289685A1 (en) | Combinations of inhibitors of irak4 with inhibitors of btk | |
| US7696201B2 (en) | Modulators of muscarinic receptors | |
| JP2016519096A5 (https=) | ||
| IL258577A (en) | 2,4-dihydroxy-nicotinamides as apj agonists | |
| JP2019509319A5 (https=) | ||
| JP2012528178A5 (https=) | ||
| JP2009541311A5 (https=) | ||
| JP2013526536A5 (https=) | ||
| JP2013531070A5 (https=) | ||
| JP2018530591A5 (https=) | ||
| EP3661560A1 (en) | Combination of atr kinase inhibitors and pd-1/pd-l1 inhibitors | |
| JP2016514718A5 (https=) | ||
| JP2014531465A5 (https=) | ||
| CA2642922A1 (en) | Melanocortin type 4 receptor agonist piperidinoylpyrrolidines | |
| JPWO2021257418A5 (https=) | ||
| JP2009507758A5 (https=) | ||
| JP2016530299A5 (https=) | ||
| CA3016081A1 (en) | Compositions and combinations of autotaxin inhibitors | |
| KR20120099650A (ko) | Ｂｃｒ-ａｂｌ, ｃ-ｋｉｔ, ｄｄｒ1, ｄｄｒ2 또는 ｐｄｇｆ-ｒ 키나제 활성에 의해 매개된 증식성 장애 및 다른 병적 상태의 치료 방법 | |
| CA3054247A1 (en) | Combination of atr kinase inhibitors with parp inhibitors |