JP2021505598A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021505598A5 JP2021505598A5 JP2020530969A JP2020530969A JP2021505598A5 JP 2021505598 A5 JP2021505598 A5 JP 2021505598A5 JP 2020530969 A JP2020530969 A JP 2020530969A JP 2020530969 A JP2020530969 A JP 2020530969A JP 2021505598 A5 JP2021505598 A5 JP 2021505598A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- methyl
- dihydro
- pyridine
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 **N(CC1)CCC1(C1)OCC1NCC(COc1cccc(S(N(*)*)(=O)=O)c1)O Chemical compound **N(CC1)CCC1(C1)OCC1NCC(COc1cccc(S(N(*)*)(=O)=O)c1)O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762595133P | 2017-12-06 | 2017-12-06 | |
| US62/595,133 | 2017-12-06 | ||
| PCT/US2018/064316 WO2019113359A1 (en) | 2017-12-06 | 2018-12-06 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021505598A JP2021505598A (ja) | 2021-02-18 |
| JP2021505598A5 true JP2021505598A5 (https=) | 2022-01-11 |
| JP7357617B2 JP7357617B2 (ja) | 2023-10-06 |
Family
ID=64744985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020530969A Active JP7357617B2 (ja) | 2017-12-06 | 2018-12-06 | 心不全およびそれに関連する障害の治療または予防に有用なβ－３アドレナリン受容体のモジュレーター |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11339172B2 (https=) |
| EP (1) | EP3720858B1 (https=) |
| JP (1) | JP7357617B2 (https=) |
| CN (1) | CN111699189B (https=) |
| AR (1) | AR114156A1 (https=) |
| ES (1) | ES2953576T3 (https=) |
| MA (1) | MA51015A (https=) |
| TW (1) | TWI822713B (https=) |
| WO (1) | WO2019113359A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA44037B1 (fr) | 2016-06-06 | 2020-03-31 | Arena Pharm Inc | Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci |
| ES2747768T3 (es) | 2017-03-20 | 2020-03-11 | Forma Therapeutics Inc | Composiciones de pirrolopirrol como activadores de quinasa de piruvato (PKR) |
| CN111699189B (zh) * | 2017-12-06 | 2025-02-18 | 艾尼纳制药公司 | 可用于治疗或预防与其相关的心力衰竭和障碍的β-3肾上腺素能受体的调节剂 |
| ES2989438T3 (es) | 2018-09-19 | 2024-11-26 | Novo Nordisk Healthcare Ag | Activación de la piruvato cinasa R |
| US12053458B2 (en) | 2018-09-19 | 2024-08-06 | Novo Nordisk Health Care Ag | Treating sickle cell disease with a pyruvate kinase R activating compound |
| US20220378756A1 (en) | 2019-09-19 | 2022-12-01 | Forma Therapeutics, Inc. | Activating pyruvate kinase r |
| US12128035B2 (en) | 2021-03-19 | 2024-10-29 | Novo Nordisk Health Care Ag | Activating pyruvate kinase R |
| US20250127773A1 (en) * | 2021-08-09 | 2025-04-24 | Arena Pharmaceuticals, Inc. | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure |
| JP2024532227A (ja) | 2021-08-26 | 2024-09-05 | アリーナ ファーマシューティカルズ， インコーポレイテッド | 腎嚢胞性疾患および心腎症候群の処置または予防のためのベータ３アドレナリン作動性受容体のモジュレーター |
| US20240409548A1 (en) | 2021-10-06 | 2024-12-12 | Arena Pharmaceuticals, Inc. | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| FR2755439B1 (fr) | 1996-11-05 | 1998-12-24 | Virbac Sa | Derives aryloxypropanolamines, leur procede de preparation et leurs applications |
| JP4782342B2 (ja) | 1999-12-17 | 2011-09-28 | サノフィ−アベンティス | フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物 |
| CZ20031012A3 (en) * | 2000-10-20 | 2004-04-14 | Pfizer Products Inc. | Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists |
| US20080255134A1 (en) | 2004-11-30 | 2008-10-16 | Artesian Therapeutics, Inc. | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase |
| PT3206678T (pt) | 2014-10-14 | 2020-03-23 | Sculpt B V | Escultura corporal |
| MA44037B1 (fr) * | 2016-06-06 | 2020-03-31 | Arena Pharm Inc | Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci |
| CN111699189B (zh) | 2017-12-06 | 2025-02-18 | 艾尼纳制药公司 | 可用于治疗或预防与其相关的心力衰竭和障碍的β-3肾上腺素能受体的调节剂 |
-
2018
- 2018-12-06 CN CN201880088219.8A patent/CN111699189B/zh active Active
- 2018-12-06 WO PCT/US2018/064316 patent/WO2019113359A1/en not_active Ceased
- 2018-12-06 TW TW107143855A patent/TWI822713B/zh active
- 2018-12-06 MA MA051015A patent/MA51015A/fr unknown
- 2018-12-06 EP EP18822236.8A patent/EP3720858B1/en active Active
- 2018-12-06 JP JP2020530969A patent/JP7357617B2/ja active Active
- 2018-12-06 ES ES18822236T patent/ES2953576T3/es active Active
- 2018-12-06 US US16/769,507 patent/US11339172B2/en active Active
- 2018-12-06 AR ARP180103577A patent/AR114156A1/es unknown
-
2022
- 2022-04-22 US US17/726,807 patent/US11987588B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021505598A5 (https=) | ||
| US20250059181A1 (en) | Tetrahydro-Pyrido-Pyrimidine Derivatives | |
| EP2549875B1 (en) | Soluble guanylate cyclase activators | |
| CA2486187C (en) | Kinase inhibitors | |
| AU2012354094C1 (en) | Use of inhibitors of the activity or function of PI3K | |
| US9181272B2 (en) | Aldosterone synthase inhibitors | |
| WO2024238574A1 (en) | Cdk inhibitor compounds | |
| HRP20180413T1 (hr) | Inhibitori kinaza koji reguliraju signalne puteve u apoptozi | |
| AU2004226165A1 (en) | Pyrimidin-4-one derivatives and their use as p38 kinase modulators | |
| JP2013501002A (ja) | Ｓｙｋキナーゼ阻害剤としての化合物および組成物 | |
| CA2816594A1 (en) | Nampt and rock inhibitors | |
| JP2016520116A (ja) | イミダゾピロリジノン誘導体および疾患の処置におけるその使用 | |
| KR102719137B1 (ko) | 3-((헤테로-)아릴)-8-아미노-2-옥소-1,3-디아자-스파이로-[4.5]-데칸 유도체 | |
| JP2021505598A (ja) | 心不全およびそれに関連する障害の治療または予防に有用なβ−３アドレナリン受容体のモジュレーター | |
| TW202337457A (zh) | 新穎苯并咪唑吡啶衍生物 | |
| AU2014253493B2 (en) | Tetrahydro-pyrido-pyrimidine derivatives |