JP2021505526A5 - - Google Patents
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- Publication number
- JP2021505526A5 JP2021505526A5 JP2020521320A JP2020521320A JP2021505526A5 JP 2021505526 A5 JP2021505526 A5 JP 2021505526A5 JP 2020521320 A JP2020521320 A JP 2020521320A JP 2020521320 A JP2020521320 A JP 2020521320A JP 2021505526 A5 JP2021505526 A5 JP 2021505526A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- use according
- inhibitor
- combination
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023082991A JP2023109899A (ja) | 2017-10-31 | 2023-05-19 | 少なくとも１つのスプライソソームモジュレーターと、ｂｃｌ２阻害剤、ｂｃｌ２／ｂｃｌｘｌ阻害剤及びｂｃｌｘｌ阻害剤から選択される少なくとも１つの阻害剤とを含む組合せ、並びに使用の方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762579666P | 2017-10-31 | 2017-10-31 | |
| US62/579,666 | 2017-10-31 | ||
| US201762580364P | 2017-11-01 | 2017-11-01 | |
| US62/580,364 | 2017-11-01 | ||
| PCT/US2018/058277 WO2019089641A1 (en) | 2017-10-31 | 2018-10-30 | Combination comprising at least one spliceosome modulator and at least one inhibitor chosen from bcl2 inhibitors, bcl2/bclxl inhibitors, and bclxl inhibitors and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023082991A Division JP2023109899A (ja) | 2017-10-31 | 2023-05-19 | 少なくとも１つのスプライソソームモジュレーターと、ｂｃｌ２阻害剤、ｂｃｌ２／ｂｃｌｘｌ阻害剤及びｂｃｌｘｌ阻害剤から選択される少なくとも１つの阻害剤とを含む組合せ、並びに使用の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021505526A JP2021505526A (ja) | 2021-02-18 |
| JP2021505526A5 true JP2021505526A5 (https=) | 2021-12-02 |
Family
ID=64277937
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020521320A Pending JP2021505526A (ja) | 2017-10-31 | 2018-10-30 | 少なくとも１つのスプライソソームモジュレーターと、ｂｃｌ２阻害剤、ｂｃｌ２／ｂｃｌｘｌ阻害剤及びｂｃｌｘｌ阻害剤から選択される少なくとも１つの阻害剤とを含む組合せ、並びに使用の方法 |
| JP2023082991A Pending JP2023109899A (ja) | 2017-10-31 | 2023-05-19 | 少なくとも１つのスプライソソームモジュレーターと、ｂｃｌ２阻害剤、ｂｃｌ２／ｂｃｌｘｌ阻害剤及びｂｃｌｘｌ阻害剤から選択される少なくとも１つの阻害剤とを含む組合せ、並びに使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023082991A Pending JP2023109899A (ja) | 2017-10-31 | 2023-05-19 | 少なくとも１つのスプライソソームモジュレーターと、ｂｃｌ２阻害剤、ｂｃｌ２／ｂｃｌｘｌ阻害剤及びｂｃｌｘｌ阻害剤から選択される少なくとも１つの阻害剤とを含む組合せ、並びに使用の方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11524009B2 (https=) |
| EP (1) | EP3703755B1 (https=) |
| JP (2) | JP2021505526A (https=) |
| KR (1) | KR20200083532A (https=) |
| CN (1) | CN111727059A (https=) |
| AU (1) | AU2018360559B2 (https=) |
| BR (1) | BR112020008362A2 (https=) |
| CA (1) | CA3079089A1 (https=) |
| IL (1) | IL274150A (https=) |
| MX (1) | MX2020004179A (https=) |
| SG (1) | SG11202003197TA (https=) |
| WO (1) | WO2019089641A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020092528A1 (en) | 2018-10-31 | 2020-05-07 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity |
| US11203591B2 (en) | 2018-10-31 | 2021-12-21 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds |
| EP3972695A1 (en) | 2019-05-23 | 2022-03-30 | Gilead Sciences, Inc. | Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors |
| EP4051286A1 (en) * | 2019-10-29 | 2022-09-07 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods and compositions for treating uveal melanoma |
| AU2021284401A1 (en) * | 2020-06-05 | 2023-01-05 | Eisai R&D Management Co., Ltd. | Anti-BCMA antibody-drug conjugates and methods of use |
| ES2919898B8 (es) * | 2021-01-27 | 2024-02-02 | Fundacion Univ San Antonio | Nuevo tratamiento del cáncer colorrectal |
| CN112691195B (zh) * | 2021-02-02 | 2023-03-14 | 黑龙江省科学院高技术研究院 | Prpf8表达抑制剂在制备治疗肺癌的药物中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI312681B (en) | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| CA2494536C (en) | 2002-07-31 | 2011-10-04 | Mercian Corporation | A 12-membered ring macrolide active substance |
| JP4459051B2 (ja) | 2002-07-31 | 2010-04-28 | メルシャン株式会社 | 新規生理活性物質 |
| AU2003285012A1 (en) | 2002-10-24 | 2004-05-13 | Sepracor, Inc. | Compositions comprising zopiclone derivatives and methods of making and using the same |
| BR0316746A (pt) | 2002-11-29 | 2005-10-18 | Mercian Corp | Método de produção do composto macrolida 11107d, linhagem streptomyces sp.ab-1704 (ferm bp-8551), linhagem mortierella sp. f1529 (ferm bp-8547) ou linhagem f-1530 (ferm bp-8548), e linhagem ab-1896 (ferm bp-8550) |
| CN1886505A (zh) | 2003-11-27 | 2006-12-27 | 美露香株式会社 | 参与大环内酯类化合物的羟化作用的dna |
| US8008049B2 (en) | 2004-07-20 | 2011-08-30 | Eisai R&D Management Co., Ltd. | DNA coding for polypeptide participating in biosynthesis of pladienolide |
| EP1792622A1 (en) * | 2005-11-11 | 2007-06-06 | GPC Biotech AG | Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues |
| US20080312317A1 (en) | 2007-04-12 | 2008-12-18 | Eisai R&D Management Co., Ltd. | 12 membered-ring macrolactam derivatives |
| JP2011530511A (ja) * | 2008-08-05 | 2011-12-22 | メルク・シャープ・エンド・ドーム・コーポレイション | 治療用化合物 |
| US8211928B2 (en) | 2009-05-29 | 2012-07-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2014089571A1 (en) * | 2012-12-09 | 2014-06-12 | St. Jude Children's Research Hospital | Anticancer compounds |
| US20150313906A1 (en) * | 2012-12-19 | 2015-11-05 | Glaxosmithkline Llc | Combination |
| CA2919790C (en) * | 2013-08-02 | 2018-06-19 | Pfizer Inc. | Anti-cxcr4 antibodies and antibody-drug conjugates |
| LT3143016T (lt) | 2014-05-15 | 2019-06-10 | Eisai R&D Management Co., Ltd. | Pladienolido piridino junginiai ir panaudojimo būdai |
| CA3103604C (en) * | 2016-03-28 | 2023-09-26 | Presage Biosciences, Inc. | Pharmaceutical combinations for the treatment of cancer |
-
2018
- 2018-10-30 MX MX2020004179A patent/MX2020004179A/es unknown
- 2018-10-30 JP JP2020521320A patent/JP2021505526A/ja active Pending
- 2018-10-30 AU AU2018360559A patent/AU2018360559B2/en not_active Expired - Fee Related
- 2018-10-30 BR BR112020008362-3A patent/BR112020008362A2/pt not_active IP Right Cessation
- 2018-10-30 CA CA3079089A patent/CA3079089A1/en active Pending
- 2018-10-30 KR KR1020207015324A patent/KR20200083532A/ko active Pending
- 2018-10-30 SG SG11202003197TA patent/SG11202003197TA/en unknown
- 2018-10-30 US US16/760,313 patent/US11524009B2/en active Active
- 2018-10-30 WO PCT/US2018/058277 patent/WO2019089641A1/en not_active Ceased
- 2018-10-30 CN CN201880070827.6A patent/CN111727059A/zh active Pending
- 2018-10-30 EP EP18801253.8A patent/EP3703755B1/en active Active
-
2020
- 2020-04-22 IL IL274150A patent/IL274150A/en unknown
-
2023
- 2023-05-19 JP JP2023082991A patent/JP2023109899A/ja active Pending
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