JP2021503610A5 - - Google Patents
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- JP2021503610A5 JP2021503610A5 JP2020545038A JP2020545038A JP2021503610A5 JP 2021503610 A5 JP2021503610 A5 JP 2021503610A5 JP 2020545038 A JP2020545038 A JP 2020545038A JP 2020545038 A JP2020545038 A JP 2020545038A JP 2021503610 A5 JP2021503610 A5 JP 2021503610A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- biomarker
- subject
- detecting
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000090 biomarker Substances 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 208000001183 Brain Injury Diseases 0.000 claims 1
- 206010052639 Nerve injury Diseases 0.000 claims 1
- 238000003556 assay method Methods 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 231100000874 brain damage Toxicity 0.000 claims 1
- 238000002331 protein detection Methods 0.000 claims 1
Claims (1)
- 対象における神経損傷または脳損傷を示す、タンパク質バイオマーカー、またはこれに由来するペプチドバイオマーカーを検出する方法であって、前記方法が、１つ以上のタンパク質バイオマーカー、またはこれに由来するペプチドバイオマーカーが、前記対象から採取した生体サンプル中に存在するか否かタンパク質検出測定法を用いることにより検出することを含み、前記１つ以上のタンパク質バイオマーカーが表１のタンパク質番号１〜８１から選択される前記方法。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024001282A JP2024038290A (ja) | 2017-11-16 | 2024-01-09 | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762587272P | 2017-11-16 | 2017-11-16 | |
| US62/587,272 | 2017-11-16 | ||
| PCT/US2018/061372 WO2019099732A1 (en) | 2017-11-16 | 2018-11-15 | Protein biomarker indicators of neurological injury and/or disease and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001282A Division JP2024038290A (ja) | 2017-11-16 | 2024-01-09 | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021503610A JP2021503610A (ja) | 2021-02-12 |
| JP2021503610A5 true JP2021503610A5 (ja) | 2021-12-23 |
| JPWO2019099732A5 JPWO2019099732A5 (ja) | 2022-09-28 |
Family
ID=66538796
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020545038A Pending JP2021503610A (ja) | 2017-11-16 | 2018-11-15 | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
| JP2024001282A Pending JP2024038290A (ja) | 2017-11-16 | 2024-01-09 | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001282A Pending JP2024038290A (ja) | 2017-11-16 | 2024-01-09 | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11988676B2 (ja) |
| EP (1) | EP3710836A4 (ja) |
| JP (2) | JP2021503610A (ja) |
| WO (1) | WO2019099732A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3779448A1 (en) * | 2019-08-12 | 2021-02-17 | Baden-Württemberg Stiftung gGmbH | Novel diagnostic marker for creutzfeldt-jakob disease and alzheimer's disease |
| US20220326258A1 (en) * | 2019-09-13 | 2022-10-13 | Northwestern University | Biomarkers for amyotrophic lateral sclerosis (als) and motor neuron diseases |
| EP4111197A1 (en) * | 2020-02-25 | 2023-01-04 | Markus Otto | Diagnosing a disease associated with synaptic degeneration using an elisa for determining a beta-synuclein concentration in csf |
| EP4296671A1 (en) * | 2021-02-17 | 2023-12-27 | Fujita Academy | Marker for lymphocytic adenohypophysitis and related diseases, and use of said marker |
| WO2023092157A1 (en) * | 2021-11-22 | 2023-05-25 | Brainbox Solutions, Inc. | Biomarker testing for chronic persistent injury following brain trauma |
| WO2024050133A1 (en) * | 2022-09-01 | 2024-03-07 | GATC Health Corp | Digital twin for diagnostic and therapeutic use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60233949D1 (de) * | 2001-08-20 | 2009-11-19 | Biosite Inc | Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon |
| CA2804763C (en) * | 2010-07-14 | 2023-01-03 | The Regents Of The University Of California | Biomarkers for diagnosis of transient ischemic attacks |
| AU2011334548B2 (en) * | 2010-11-26 | 2016-06-09 | Immunexpress Pty Ltd | Diagnostic and/or screening agents and uses therefor |
| EP2607900A1 (de) * | 2011-12-22 | 2013-06-26 | Protagen AG | Markersequenzen für Brustkrebs und deren Verwendung |
| EP3274709B1 (en) * | 2015-03-27 | 2021-07-07 | The Translational Genomics Research Institute | Methods of prognosing mild traumatic brain injuries |
| US10557859B2 (en) * | 2015-05-05 | 2020-02-11 | The Regents Of The University Of California | Astrocyte traumatome and neurotrauma biomarkers |
| CN107923917A (zh) | 2015-06-18 | 2018-04-17 | 西达-赛奈医疗中心 | 瓜氨酸化在诊断疾病中的作用 |
| US20170145506A1 (en) * | 2015-11-24 | 2017-05-25 | University Of Rochester | Signature of Longitudinal Gene Expression Changes to Diagnose Brain Injury |
-
2018
- 2018-11-15 US US16/763,794 patent/US11988676B2/en active Active
- 2018-11-15 EP EP18879163.6A patent/EP3710836A4/en active Pending
- 2018-11-15 JP JP2020545038A patent/JP2021503610A/ja active Pending
- 2018-11-15 WO PCT/US2018/061372 patent/WO2019099732A1/en unknown
-
2024
- 2024-01-09 JP JP2024001282A patent/JP2024038290A/ja active Pending
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