JP2021502077A5 - - Google Patents

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Publication number
JP2021502077A5
JP2021502077A5 JP2020524627A JP2020524627A JP2021502077A5 JP 2021502077 A5 JP2021502077 A5 JP 2021502077A5 JP 2020524627 A JP2020524627 A JP 2020524627A JP 2020524627 A JP2020524627 A JP 2020524627A JP 2021502077 A5 JP2021502077 A5 JP 2021502077A5
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JP
Japan
Prior art keywords
cblb
gene
cells
immune cells
grna
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JP2020524627A
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English (en)
Japanese (ja)
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JP2021502077A (ja
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Priority claimed from PCT/US2018/059146 external-priority patent/WO2019090202A1/en
Publication of JP2021502077A publication Critical patent/JP2021502077A/ja
Publication of JP2021502077A5 publication Critical patent/JP2021502077A5/ja
Priority to JP2023171022A priority Critical patent/JP2023182711A/ja
Withdrawn legal-status Critical Current

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JP2020524627A 2017-11-06 2018-11-05 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ−ｃａｓ９編集のための方法、組成物および構成要素 Withdrawn JP2021502077A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023171022A JP2023182711A (ja) 2017-11-06 2023-10-02 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物および構成要素

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762582020P 2017-11-06 2017-11-06
US62/582,020 2017-11-06
US201762582393P 2017-11-07 2017-11-07
US62/582,393 2017-11-07
PCT/US2018/059146 WO2019090202A1 (en) 2017-11-06 2018-11-05 Methods, compositions and components for crispr-cas9 editing of cblb in t cells for immunotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023171022A Division JP2023182711A (ja) 2017-11-06 2023-10-02 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物および構成要素

Publications (2)

Publication Number Publication Date
JP2021502077A JP2021502077A (ja) 2021-01-28
JP2021502077A5 true JP2021502077A5 (https=) 2021-12-09

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ID=64564989

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Application Number Title Priority Date Filing Date
JP2020524627A Withdrawn JP2021502077A (ja) 2017-11-06 2018-11-05 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ−ｃａｓ９編集のための方法、組成物および構成要素
JP2023171022A Withdrawn JP2023182711A (ja) 2017-11-06 2023-10-02 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物および構成要素

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023171022A Withdrawn JP2023182711A (ja) 2017-11-06 2023-10-02 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物および構成要素

Country Status (6)

Country Link
US (2) US20230137729A1 (https=)
EP (1) EP3707258A1 (https=)
JP (2) JP2021502077A (https=)
KR (1) KR20200079312A (https=)
CN (1) CN111556893A (https=)
WO (1) WO2019090202A1 (https=)

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CN114250228A (zh) * 2020-09-22 2022-03-29 广州瑞风生物科技有限公司 靶向CTGF基因的gRNA及其应用
EP4255453A4 (en) * 2020-12-03 2025-03-26 Nkarta, Inc. Methods for manipulating immune cells for increased potency and persistence, as well as uses of engineered cells in immunotherapy
WO2022150392A1 (en) 2021-01-05 2022-07-14 City Of Hope Natural killer cells engineered to reduce or eliminate cbl-b and uses thereof
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