KR20200079312A - 면역요법을 위한 t 세포 내 cblb의 crispr-cas9 편집 방법, 조성물 및 성분 - Google Patents

면역요법을 위한 t 세포 내 cblb의 crispr-cas9 편집 방법, 조성물 및 성분 Download PDF

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KR20200079312A
KR20200079312A KR1020207016277A KR20207016277A KR20200079312A KR 20200079312 A KR20200079312 A KR 20200079312A KR 1020207016277 A KR1020207016277 A KR 1020207016277A KR 20207016277 A KR20207016277 A KR 20207016277A KR 20200079312 A KR20200079312 A KR 20200079312A
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안드레이아 에스. 코스타
제이슨 데이비드 폰테노
프레드 하빈스키
조던 그랜트 웰스테드
크리스 윌슨
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에디타스 메디신, 인코포레이티드
주노 쎄러퓨티크스 인코퍼레이티드
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    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]

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KR1020207016277A 2017-11-06 2018-11-05 면역요법을 위한 t 세포 내 cblb의 crispr-cas9 편집 방법, 조성물 및 성분 Ceased KR20200079312A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762582020P 2017-11-06 2017-11-06
US62/582,020 2017-11-06
US201762582393P 2017-11-07 2017-11-07
US62/582,393 2017-11-07
PCT/US2018/059146 WO2019090202A1 (en) 2017-11-06 2018-11-05 Methods, compositions and components for crispr-cas9 editing of cblb in t cells for immunotherapy

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KR20200079312A true KR20200079312A (ko) 2020-07-02

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US (2) US20230137729A1 (https=)
EP (1) EP3707258A1 (https=)
JP (2) JP2021502077A (https=)
KR (1) KR20200079312A (https=)
CN (1) CN111556893A (https=)
WO (1) WO2019090202A1 (https=)

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WO2022150392A1 (en) 2021-01-05 2022-07-14 City Of Hope Natural killer cells engineered to reduce or eliminate cbl-b and uses thereof
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US20230346836A1 (en) * 2021-12-22 2023-11-02 Crispr Therapeutics Ag Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof
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WO2024064642A2 (en) * 2022-09-19 2024-03-28 Tune Therapeutics, Inc. Compositions, systems, and methods for modulating t cell function

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CN111556893A (zh) 2020-08-18
US20260002159A1 (en) 2026-01-01
WO2019090202A1 (en) 2019-05-09
JP2023182711A (ja) 2023-12-26
US20230137729A1 (en) 2023-05-04
EP3707258A1 (en) 2020-09-16
JP2021502077A (ja) 2021-01-28

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