JP2021501321A - 組織および細胞染色のためのデバイスおよび方法 - Google Patents

組織および細胞染色のためのデバイスおよび方法 Download PDF

Info

Publication number
JP2021501321A
JP2021501321A JP2020523788A JP2020523788A JP2021501321A JP 2021501321 A JP2021501321 A JP 2021501321A JP 2020523788 A JP2020523788 A JP 2020523788A JP 2020523788 A JP2020523788 A JP 2020523788A JP 2021501321 A JP2021501321 A JP 2021501321A
Authority
JP
Japan
Prior art keywords
sample
plates
plate
spacer
stain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020523788A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021501321A5 (https=
Inventor
スティーブン ワイ． チョウ
スティーブン ワイ． チョウ
ウェイ ディン
ウェイ ディン
ジ リ
ジ リ
シェン−チャン カイ
シェン−チャン カイ
Original Assignee
エッセンリックス コーポレーション
エッセンリックス コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エッセンリックス コーポレーション, エッセンリックス コーポレーション filed Critical エッセンリックス コーポレーション
Publication of JP2021501321A publication Critical patent/JP2021501321A/ja
Publication of JP2021501321A5 publication Critical patent/JP2021501321A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6893—Cars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Flexible containers without fluid transport within
    • B01L3/5055—Hinged, e.g. opposable surfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724—User interfaces specially adapted for cordless or mobile telephones
    • H04M1/72403—User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
    • H04M1/72409—User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality by interfacing with external accessories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302—Stain compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/036—Cuvette constructions transformable, modifiable
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0389—Windows
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/651—Cuvettes therefore
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G01N21/69—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Human Computer Interaction (AREA)
  • Biophysics (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ecology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2020523788A 2017-10-26 2018-10-26 組織および細胞染色のためのデバイスおよび方法 Pending JP2021501321A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762577347P 2017-10-26 2017-10-26
US62/577,347 2017-10-26
PCT/US2018/057875 WO2019084515A1 (en) 2017-10-26 2018-10-26 DEVICES AND METHODS FOR COLORING TISSUES AND CELLS

Publications (2)

Publication Number Publication Date
JP2021501321A true JP2021501321A (ja) 2021-01-14
JP2021501321A5 JP2021501321A5 (https=) 2021-12-02

Family

ID=66246756

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020523788A Pending JP2021501321A (ja) 2017-10-26 2018-10-26 組織および細胞染色のためのデバイスおよび方法

Country Status (5)

Country Link
US (2) US11326989B2 (https=)
EP (1) EP3700420B1 (https=)
JP (1) JP2021501321A (https=)
CN (1) CN112218577A (https=)
WO (1) WO2019084515A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024057329A1 (en) * 2022-09-16 2024-03-21 Bhattacharyya Neha Fluorometric sensory arrays for the detection of urinary bladder cancer-related vocs

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3837543A4 (en) * 2018-08-16 2022-11-16 Essenlix Corporation CELL ANALYSIS IN BODY FLUID, ESPECIALLY BLOOD
US12169167B2 (en) * 2019-01-15 2024-12-17 Essenlix Corporation Devices and methods for tissue and cell staining (II)
US11210554B2 (en) * 2019-03-21 2021-12-28 Illumina, Inc. Artificial intelligence-based generation of sequencing metadata
CN113795744B (zh) * 2019-05-13 2025-03-18 通用表面增强光谱学有限公司 一种用于确定流体样品中的颗粒特性和/或用于确定流体样品的污染特性的方法
WO2020247409A1 (en) * 2019-06-02 2020-12-10 Essenlix Corporation Fast staining of biomaterials enhanced by image processing and artificial intelligence
WO2021011944A2 (en) * 2019-07-18 2021-01-21 Essenlix Corporation Imaging based homogeneous assay
EP4193299B1 (en) * 2020-08-04 2026-04-01 PAIGE.AI, Inc. Systems and methods to process electronic images to provide image-based cell group targeting
WO2022136848A1 (en) * 2020-12-22 2022-06-30 Oxford Immune Algorithmics Ltd Wafer for carrying biological sample
WO2022159627A1 (en) * 2021-01-20 2022-07-28 Rebus Biosystems, Inc. Spatial rna localization method
US12525320B2 (en) 2021-03-16 2026-01-13 Illumina, Inc. Neural network parameter quantization for base calling
CN112986215B (zh) * 2021-04-20 2022-08-02 江南大学 一种基于表面增强拉曼光谱技术检测牛奶中苯甲酸的方法
CN113567217A (zh) * 2021-07-27 2021-10-29 肖波 一种妇科荧光染色液
CN114441271B (zh) * 2021-12-27 2023-06-27 桂林优利特医疗电子有限公司 一种新型染色液的配置及染色方法
CN114252324B (zh) * 2022-03-02 2022-05-13 中国人民解放军军事科学院军事医学研究院 一种方便使用的多孔脑片孵育装置
CN114624084A (zh) * 2022-03-18 2022-06-14 深圳市贝安特医疗技术有限公司 一种病理组织切片染色试剂盒的制备、染色方法
CN115372350A (zh) * 2022-09-02 2022-11-22 中迅优检生物科技(江苏)有限公司 一种游离血红素单检双判方法
WO2025158393A1 (en) * 2024-01-24 2025-07-31 The Regents Of The University Of Michigan Cell typing with cell lasing
CN118670828A (zh) * 2024-07-17 2024-09-20 甘肃农业大学 一种用于观察双子叶植物木质化程度石蜡切片的制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09281017A (ja) * 1996-02-15 1997-10-31 Aloka Co Ltd 生物組織の処理装置
JPH10221336A (ja) * 1997-01-31 1998-08-21 Abx Sa 染色試薬
US20020182623A1 (en) * 2001-02-23 2002-12-05 Didier Lefevre Reagent and process for the identification and counting of biological cells
JP2009502117A (ja) * 2005-05-24 2009-01-29 アベスタゲン リミテッド 赤血球新生刺激タンパク質生成のための組み換え法
WO2016042830A1 (ja) * 2014-09-16 2016-03-24 富士フイルム株式会社 胎児染色体の解析方法
WO2017048871A1 (en) * 2015-09-14 2017-03-23 Essenlix Corp. Device and system for analyzing a sample, particularly blood, as well as methods of using the same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3063985B2 (ja) * 1989-08-10 2000-07-12 株式会社北里サプライ 使い捨て検査用具
US6391568B1 (en) * 1998-07-15 2002-05-21 Lionheart Technologies, Inc. Method for determining platelet reactivity in a whole blood sample
US6586259B1 (en) * 1999-11-15 2003-07-01 Pharmanetics Incorporated Platelet/leukocyte interaction assay and reagent therefor
US7943093B2 (en) * 2001-12-12 2011-05-17 Erie Scientific Company Cover slip
JP2008032420A (ja) * 2006-07-26 2008-02-14 National Institute Of Advanced Industrial & Technology エバネッセント励起蛍光観察における背景蛍光を減弱する方法及び部材
CN103328979B (zh) * 2010-12-06 2015-10-07 丹麦达科有限公司 组合的组织学染色
US9448151B2 (en) * 2011-10-22 2016-09-20 Lightintegra Technology Inc. Apparatus and method for platelet monitoring and for assessing the quality of platelets
WO2013075736A1 (en) * 2011-11-22 2013-05-30 Luxcel Biosciences Limited Device and method for rapid assay of multiple biological samples for oxygen consumption
WO2015175188A1 (en) * 2014-05-14 2015-11-19 General Electric Company Microfluidic flow cell assemblies for imaging and method of use
US9891209B2 (en) * 2015-05-29 2018-02-13 C A Casyso Gmbh Electrode assembly for measurement of platelet function in whole blood
CN113376364B (zh) * 2015-08-10 2025-02-25 上海宜晟生物科技有限公司 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法
MX392709B (es) 2015-09-14 2025-03-24 Essenlix Corp Dispositivo y sistema para recolectar y analizar condensado de vapor, particularmente condensado de exhalación de la respiración y un método para usarlo.
KR20170099739A (ko) * 2016-02-23 2017-09-01 노을 주식회사 접촉식 염색 보조 패치, 그 제조 방법 및 이를 이용하는 염색 방법
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
EP3723611A4 (en) * 2017-12-14 2021-11-03 Essenlix Corporation ENHANCED OPTICAL TRANSMISSION SAMPLE HOLDER AND FOR ANALYSIS, ESPECIALLY FOR HEMOGLOBIN

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09281017A (ja) * 1996-02-15 1997-10-31 Aloka Co Ltd 生物組織の処理装置
JPH10221336A (ja) * 1997-01-31 1998-08-21 Abx Sa 染色試薬
US20020182623A1 (en) * 2001-02-23 2002-12-05 Didier Lefevre Reagent and process for the identification and counting of biological cells
JP2009502117A (ja) * 2005-05-24 2009-01-29 アベスタゲン リミテッド 赤血球新生刺激タンパク質生成のための組み換え法
WO2016042830A1 (ja) * 2014-09-16 2016-03-24 富士フイルム株式会社 胎児染色体の解析方法
WO2017048871A1 (en) * 2015-09-14 2017-03-23 Essenlix Corp. Device and system for analyzing a sample, particularly blood, as well as methods of using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024057329A1 (en) * 2022-09-16 2024-03-21 Bhattacharyya Neha Fluorometric sensory arrays for the detection of urinary bladder cancer-related vocs

Also Published As

Publication number Publication date
US11326989B2 (en) 2022-05-10
EP3700420B1 (en) 2024-09-25
US20200378875A1 (en) 2020-12-03
US20230014031A1 (en) 2023-01-19
WO2019084515A1 (en) 2019-05-02
EP3700420A4 (en) 2021-07-28
CN112218577A (zh) 2021-01-12
EP3700420A1 (en) 2020-09-02

Similar Documents

Publication Publication Date Title
US20230014031A1 (en) Devices and methods for tissue and cell staining
JP7004732B2 (ja) 異なる間隔の高さを使用するアッセイ法
US11609224B2 (en) Devices and methods for white blood cell analyses
WO2019140334A1 (en) Homogeneous assay (ii)
US20210181085A1 (en) Rapid measurement of platelets
US20250353014A1 (en) Devices and methods for platelet assay
US20200333322A1 (en) Assays with reduced interference
US20250283817A1 (en) Multi-mode illumination system
US11280706B2 (en) Dilution calibration
US11796538B2 (en) Sample collection, holding and assaying
US11536941B2 (en) Planar area light source

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20210121

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20211021

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20211021

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220930

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221017

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230113

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230417

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20230607

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230731

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20231027

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20240208

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240402