CN112218577A - 用于组织和细胞染色的装置和方法 - Google Patents

用于组织和细胞染色的装置和方法 Download PDF

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Publication number
CN112218577A
CN112218577A CN201880083342.0A CN201880083342A CN112218577A CN 112218577 A CN112218577 A CN 112218577A CN 201880083342 A CN201880083342 A CN 201880083342A CN 112218577 A CN112218577 A CN 112218577A
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斯蒂芬·Y·周
丁惟
李骥
蔡声建
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Shanghai Yisheng Biotechnology Co ltd
Yewei Co ltd
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Essenlix Corp
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    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
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    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
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    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
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    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/47—Scattering, i.e. diffuse reflection
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    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G01N21/69—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
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  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
CN201880083342.0A 2017-10-26 2018-10-26 用于组织和细胞染色的装置和方法 Pending CN112218577A (zh)

Applications Claiming Priority (3)

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US201762577347P 2017-10-26 2017-10-26
US62/577,347 2017-10-26
PCT/US2018/057875 WO2019084515A1 (en) 2017-10-26 2018-10-26 DEVICES AND METHODS FOR COLORING TISSUES AND CELLS

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US (2) US11326989B2 (https=)
EP (1) EP3700420B1 (https=)
JP (1) JP2021501321A (https=)
CN (1) CN112218577A (https=)
WO (1) WO2019084515A1 (https=)

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CN112986215A (zh) * 2021-04-20 2021-06-18 江南大学 一种基于表面增强拉曼光谱技术检测牛奶中苯甲酸的方法
CN113567217A (zh) * 2021-07-27 2021-10-29 肖波 一种妇科荧光染色液
CN114441271A (zh) * 2021-12-27 2022-05-06 桂林优利特医疗电子有限公司 一种新型染色液的配置及染色方法

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US12169167B2 (en) * 2019-01-15 2024-12-17 Essenlix Corporation Devices and methods for tissue and cell staining (II)
US11210554B2 (en) * 2019-03-21 2021-12-28 Illumina, Inc. Artificial intelligence-based generation of sequencing metadata
CN113795744B (zh) * 2019-05-13 2025-03-18 通用表面增强光谱学有限公司 一种用于确定流体样品中的颗粒特性和/或用于确定流体样品的污染特性的方法
WO2020247409A1 (en) * 2019-06-02 2020-12-10 Essenlix Corporation Fast staining of biomaterials enhanced by image processing and artificial intelligence
WO2021011944A2 (en) * 2019-07-18 2021-01-21 Essenlix Corporation Imaging based homogeneous assay
EP4193299B1 (en) * 2020-08-04 2026-04-01 PAIGE.AI, Inc. Systems and methods to process electronic images to provide image-based cell group targeting
WO2022136848A1 (en) * 2020-12-22 2022-06-30 Oxford Immune Algorithmics Ltd Wafer for carrying biological sample
WO2022159627A1 (en) * 2021-01-20 2022-07-28 Rebus Biosystems, Inc. Spatial rna localization method
US12525320B2 (en) 2021-03-16 2026-01-13 Illumina, Inc. Neural network parameter quantization for base calling
CN114252324B (zh) * 2022-03-02 2022-05-13 中国人民解放军军事科学院军事医学研究院 一种方便使用的多孔脑片孵育装置
CN114624084A (zh) * 2022-03-18 2022-06-14 深圳市贝安特医疗技术有限公司 一种病理组织切片染色试剂盒的制备、染色方法
CN115372350A (zh) * 2022-09-02 2022-11-22 中迅优检生物科技(江苏)有限公司 一种游离血红素单检双判方法
WO2024057329A1 (en) * 2022-09-16 2024-03-21 Bhattacharyya Neha Fluorometric sensory arrays for the detection of urinary bladder cancer-related vocs
WO2025158393A1 (en) * 2024-01-24 2025-07-31 The Regents Of The University Of Michigan Cell typing with cell lasing
CN118670828A (zh) * 2024-07-17 2024-09-20 甘肃农业大学 一种用于观察双子叶植物木质化程度石蜡切片的制备方法

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US20200378875A1 (en) 2020-12-03
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