JP2021501318A5 - - Google Patents

Download PDF

Info

Publication number
JP2021501318A5
JP2021501318A5 JP2020523389A JP2020523389A JP2021501318A5 JP 2021501318 A5 JP2021501318 A5 JP 2021501318A5 JP 2020523389 A JP2020523389 A JP 2020523389A JP 2020523389 A JP2020523389 A JP 2020523389A JP 2021501318 A5 JP2021501318 A5 JP 2021501318A5
Authority
JP
Japan
Prior art keywords
cells
virus
disease
markers
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020523389A
Other languages
English (en)
Japanese (ja)
Other versions
JP7430136B2 (ja
JP2021501318A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/057850 external-priority patent/WO2019084493A1/en
Publication of JP2021501318A publication Critical patent/JP2021501318A/ja
Publication of JP2021501318A5 publication Critical patent/JP2021501318A5/ja
Application granted granted Critical
Publication of JP7430136B2 publication Critical patent/JP7430136B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020523389A 2017-10-27 2018-10-26 疲弊したt細胞に関連する疾患を治療するための方法および組成物 Active JP7430136B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762578193P 2017-10-27 2017-10-27
US201762578212P 2017-10-27 2017-10-27
US62/578,212 2017-10-27
US62/578,193 2017-10-27
US201862660754P 2018-04-20 2018-04-20
US62/660,754 2018-04-20
US201862661467P 2018-04-23 2018-04-23
US62/661,467 2018-04-23
PCT/US2018/057850 WO2019084493A1 (en) 2017-10-27 2018-10-26 METHODS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH SUSPECTED T CELLS

Publications (3)

Publication Number Publication Date
JP2021501318A JP2021501318A (ja) 2021-01-14
JP2021501318A5 true JP2021501318A5 (enExample) 2021-12-09
JP7430136B2 JP7430136B2 (ja) 2024-02-09

Family

ID=66246753

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020523389A Active JP7430136B2 (ja) 2017-10-27 2018-10-26 疲弊したt細胞に関連する疾患を治療するための方法および組成物

Country Status (4)

Country Link
US (2) US11906511B2 (enExample)
EP (1) EP3701041A4 (enExample)
JP (1) JP7430136B2 (enExample)
WO (1) WO2019084493A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD1083956S1 (en) * 2018-12-10 2025-07-15 Icahn School Of Medicine At Mount Sinai Display screen with a graphical user interface
WO2020246846A1 (ko) * 2019-06-05 2020-12-10 연세대학교 산학협력단 Tox에 기초한 면역 항암 요법에 대한 치료 반응 예측 방법
WO2021006316A1 (ja) * 2019-07-10 2021-01-14 国立研究開発法人国立がん研究センター がん細胞を特異的に攻撃しているt細胞を同定するための特異的マーカー
EP4055180A4 (en) * 2019-11-05 2023-12-06 Cofactor Genomics, Inc. METHODS AND SYSTEMS FOR PROCESSING COMPLEX DATA SETS USING ARTIFICIAL INTELLIGENCE AND DECONVOLUTION
CN111154835A (zh) * 2020-01-19 2020-05-15 广州基迪奥生物科技有限公司 一种ATAC-seq测序文库的构建方法
EP4133059A4 (en) * 2020-04-07 2024-10-02 University Health Network COMPOSITIONS AND METHODS FOR INCREASING CD8+ T CELL ACTIVATION AND CYTOLYTIC ACTIVITY BY DISRUPTION OF THE SAGA (SPT-ADA-GCN5-ACETYLTRANSFERASE) COMPLEX
CN115768879A (zh) 2020-04-28 2023-03-07 莱尔免疫制药公司 用于培养细胞的方法
CN111748627A (zh) * 2020-07-02 2020-10-09 北京化工大学 膀胱癌耗竭型t细胞亚群、其特征基因及其应用
CA3193687A1 (en) * 2020-09-23 2022-03-31 The Trustees Of Columbia University Metabolic augmentation to promote and enhance immune response by tcf1+ t cell repopulation
CN112501292B (zh) * 2020-11-09 2022-12-02 中国人民解放军海军军医大学 cFAM210A在制备肝癌诊断或术后预测试剂盒以及药物中的应用
EP4301773A4 (en) * 2021-03-03 2025-06-25 The Board of Trustees of the Leland Stanford Junior University POLYPEPTIDE CONSTRUCTS WITH NOVEL BINDING AFFINITY AND USES THEREOF
WO2023023269A1 (en) * 2021-08-20 2023-02-23 The Board Of Trustees Of The Leland Stanford Junior University Identification of pathogenic immune cell subsets in checkpoint inhibitor-induced myocarditis
WO2023034530A1 (en) * 2021-09-02 2023-03-09 Teon Therapeutics, Inc. Methods of improving growth and function of immune cells
WO2023060071A1 (en) * 2021-10-04 2023-04-13 H. Lee Moffitt Cancer Center And Research Institute Inc. Dna methylation signatures for predicting response to immunotherapy
CN118251487A (zh) * 2021-10-26 2024-06-25 巴黎-萨克雷大学 源自高功能性自体干细胞的t细胞免疫疗法
JP2023064788A (ja) * 2021-10-27 2023-05-12 国立大学法人京都大学 T細胞の評価方法及びt細胞評価用の組成物
CN115040538A (zh) * 2022-05-23 2022-09-13 重庆医科大学 人cxcr5+cd8+t细胞在制备治疗慢性乙型肝炎的药物中的应用
CN114752628B (zh) * 2022-05-30 2023-06-30 四川大学华西医院 C57bl/6小鼠多发性骨髓瘤模型的构建方法及应用
CN115029429B (zh) * 2022-06-02 2022-11-22 中国人民解放军总医院第五医学中心 炎症相关蛋白联合在预测art治疗敏感性中的应用
CN115040663B (zh) * 2022-06-15 2023-12-12 上海交通大学医学院附属仁济医院 溶质载体家族38成员2在制备多发性骨髓瘤治疗药物中的应用
CN115058504B (zh) * 2022-07-14 2025-07-04 广州医科大学 膀胱癌th17 cd4+t细胞亚群及其特征基因与应用
WO2024074713A1 (en) * 2022-10-07 2024-04-11 Institut National de la Santé et de la Recherche Médicale Method to generate improving car-t cells
WO2024097677A1 (en) * 2022-11-01 2024-05-10 BioLegend, Inc. Analyzing per-cell co-expression of cellular constituents
CN119700985A (zh) * 2023-09-22 2025-03-28 清华大学 Bcor和Zc3h12a在预防和治疗慢性感染中的用途
CN117017991A (zh) * 2023-09-26 2023-11-10 中山大学附属第三医院 Hdac6选择性抑制剂在制备慢性乙型病毒性肝炎抗病毒治疗药物中的应用
CN118818055A (zh) * 2024-06-05 2024-10-22 复旦大学附属华山医院 用于筛选胶质瘤dc疫苗潜在受益人群的试剂盒及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2212350B1 (en) * 2007-10-26 2013-08-28 Governing Council of the University of Toronto Treating chronic viral infection by targetting TIM-3
WO2016061456A2 (en) 2014-10-17 2016-04-21 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of t-cell exhaustion using cd39 biomarkers and modulators
WO2017075451A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
KR20190080825A (ko) * 2016-03-21 2019-07-08 다나-파버 캔서 인스티튜트 인크. T-세포 기능소실 상태-특이적 유전자 발현 조절인자 및 그 용도

Similar Documents

Publication Publication Date Title
JP2021501318A5 (enExample)
AU2019249422B2 (en) Methylation markers and targeted methylation probe panels
Bas et al. Utility of the housekeeping genes 18S rRNA, β‐actin and glyceraldehyde‐3‐phosphate‐dehydrogenase for normalization in real‐time quantitative reverse transcriptase‐polymerase chain reaction analysis of gene expression in human T lymphocytes
Ekiz et al. MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers
US10870885B2 (en) Dendritic cell response gene expression, compositions of matters and methods of use thereof
Wang The opening of pandora's box: an emerging role of long noncoding RNA in viral infections
US20190263912A1 (en) Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action
De Simone et al. CXCR3 identifies human naive CD8+ T cells with enhanced effector differentiation potential
US20190144942A1 (en) Methods for identifying and modulating immune phenotypes
WO2019079647A2 (en) IA STATISTICS FOR DEEP LEARNING AND PROBABILISTIC PROGRAMMING, ADVANCED, IN BIOSCIENCES
Davar et al. Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial
Ghosh et al. Strong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy
US20230223105A1 (en) Mitigation of statistical bias in genetic sampling
Guo et al. Comprehensive analysis of m6A RNA methylation regulators and the immune microenvironment to aid immunotherapy in pancreatic cancer
US20240167933A1 (en) Flow cytometry immunoprofiling of peripheral blood
Burchill et al. Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes
KR20190032374A (ko) 엑소좀-안내 암 치료(exosome-guided treatment of cancer)
Cristalli et al. Targeting DNA methylation machinery in pediatric solid tumors
WO2005021745A1 (ja) 肝細胞癌に関連する遺伝子
US20220136070A1 (en) Methods and systems for characterizing tumor response to immunotherapy using an immunogenic profile
Zheng et al. Multi-omics profiling identifies C1QA/B+ macrophages with multiple immune checkpoints associated with esophageal squamous cell carcinoma (ESCC) liver metastasis
CN116287158A (zh) 一种新抗原鉴定和疗效预测方法
Hou et al. Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness
Razzuoli et al. Reverse transcription real‐time PCR for detection of porcine interferon α and β genes
Li et al. Identification of immunosenescence of unconventional T cells in hepatocellular carcinoma