JP2021181414A - Vesicle composition, hair cosmetic containing the same, and stabilizer of reduced keratin - Google Patents

Abstract

To provide vesicle compositions with excellent stability of reduced keratin, and to provide hair cosmetics that can stably exert protective, repairing, and modifying powers on hair over the long term.SOLUTION: The vesicle composition of the present invention aims at improving the stability of reduced keratin having a thiol group, characterizing by containing (A) polyol, (B) polyglyceryl fatty acid ester, and (C) reduced keratin.SELECTED DRAWING: None

Description

The present invention relates to a vesicle composition having excellent stability of reduced keratin. The present invention also relates to a hair cosmetic having excellent permeability and durability to the hair application site, and having high protective power, repair power and improving power for the function and characteristics of the hair at the hair application site. Furthermore, the present invention relates to a stabilizer for reduced keratin that can improve the stability of reduced keratin.

Hair cosmetics may be used not only to make the hair look beautiful and to improve the feel of the hair, but also to protect the application site or to repair or improve the function / characteristics of the application site. As an effective ingredient when blended in hair cosmetics, for example, keratin, which is a protein contained in feathers or wool, is known to be easily adapted to hair and effective for hair repair and modification. ..

Therefore, a technique as described in Patent Document 1 is known as a cosmetic containing reduced keratin having excellent durability to the application site. Since the reduced keratin has a thiol group that can be crosslinked inside the hair, it can be crosslinked to the hair via the thiol group. As a result, the reduced keratin can continuously repair and modify hair, such as improving physical properties such as strength and elongation, as well as swelling, and forming waves.

Further, a technique as described in Patent Document 2 is known as a method for improving the permeability of an active ingredient contained in a cosmetic to an application site. By making the active ingredient vesicles, the permeability of the active ingredient to the application site can be improved. Compared with the technology as in Patent Document 3, it is excellent in convenience and can vesicle a wide range of substances.

Japanese Unexamined Patent Publication No. 6-100600 Japanese Unexamined Patent Publication No. 2018-199669 Japanese Unexamined Patent Publication No. 2015-189763

Since the reduced keratin has a thiol group, when the reduced keratin is blended in the hair cosmetic, cross-linking between the reduced keratin may occur inside the hair cosmetic via the thiol group. Therefore, there is a problem in stabilizing reduced keratin over time in hair cosmetics containing reduced keratin.

Therefore, an object of the present invention is to provide a vesicle composition having excellent stability of reduced keratin. Another object of the present invention is to provide a hair cosmetic having excellent permeability and durability to a hair application site, and having high protective, repairing and improving power at the hair application site. Furthermore, it is an object of the present invention to provide a stabilizer capable of improving the stability of reduced keratin.

As a result of intensive studies, the present inventors have found that reduced keratin is stable over time in a vesicle composition containing (A) polyol, (B) polyglycerin fatty acid ester, and (C) reduced keratin. I found it.

Further, since the reduced keratin is stabilized over time in the hair cosmetic containing the vesicle composition, the protective power, the repair power and the improving power are stabilized for a long period of time for the hair application site. Can be demonstrated.

The vesicle composition of the present invention is excellent in the stability of reduced keratin. Since the cosmetic for hair of the present invention is excellent in the stability of reduced keratin, it is possible to stably exert protective power, repair power and reforming power on the application site of hair for a long period of time. According to the stabilizer of the present invention, the stability of reduced keratin can be improved.

(1) Vesicle Composition The vesicle composition of the present invention contains (A) a polyol, (B) a polyglycerin fatty acid ester, and (C) a reduced keratin. Since the vesicle composition of the present invention is excellent in the stability of the reduced keratin, it can be used for improving the stability of the reduced keratin.

The type of the polyol (A) is not particularly limited as long as a vesicle composition can be obtained. Specific examples of the polyol (A) include glycerin, diglycerin, propylene glycol, dipropylene glycol, polyethylene glycol, and 1,3-butylene glycol. From the viewpoint of ease of vesicle formation, glycerin and 1,3-butylene glycol are preferable as the polyol (A). (A) The polyol may be used alone or in combination of two or more.

(A) The content of the polyol can be appropriately set as needed. In the vesicle composition of the present invention, the content of the polyol (A) is usually 5 to 40% by mass.

The type of the (B) polyglycerin fatty acid ester is not particularly limited as long as a vesicle composition can be obtained. (B) As the polyglycerin fatty acid ester, specifically, for example, a polyglycerin fatty acid ester obtained by esterifying one or more fatty acids selected from fatty acids having 6 to 22 carbon atoms and polyglycerin having a degree of polymerization of 5 to 20. Can be mentioned. Specific examples of the fatty acid having 6 to 22 carbon atoms include caproic acid, capric acid, caprylic acid, lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, oleic acid, linoleic acid, linolenic acid, and arachidic acid. Acids and behenic acid can be mentioned.

(B) Specific examples of the polyglycerin fatty acid ester include polyglyceryl laurate-6, polyglyceryl stearate-6, polyglyceryl laurate-10, polyglyceryl stearate-10, polyglyceryl oleate-10, and polyglyceryl isostearate-10. , Polyglyceryl-10 diisostearate, polyglyceryl-10 trioleate and the like. As the polyglycerin fatty acid ester (B), polyglyceryl laurate-10, polyglyceryl isostearate-10, polyglyceryl diisostearate-10 and the like are preferable from the viewpoint of easiness of vesicle formation. (B) The polyglycerin fatty acid ester may be used alone or in combination of two or more.

(B) The content of the polyglycerin fatty acid ester can be appropriately set as needed. The content of the (B) polyglycerin fatty acid ester in the vesicle composition of the present invention is usually 0.5 to 5% by mass. The content may be combined with the above description of the content of the polyol (A).

The blending ratio of the polyol (A) and the polyglycerin fatty acid ester (B) is not particularly limited as long as the vesicle composition can be obtained. The blending ratio of the polyol (A) and the polyglycerin fatty acid ester (B) is preferably (B) polyglycerin fatty acid ester / (A) polyol = 0.01 to 1.0 from the viewpoint of easiness of forming vesicles. It is more preferably 0.05 to 0.7, and particularly preferably 0.1 to 0.4. This makes it possible to form a highly stable vesicle. The blending ratio may be combined with the above description of the content of (A) polyol and / or (B) polyglycerin fatty acid ester.

(C) Reduced keratin is a keratin derivative having at least one thiol group. Reduced keratin is different from hydrolyzed keratin because it is reduced and extracted. (C) The method for obtaining reduced keratin is not particularly limited. (C) Reduced keratin can usually be obtained by reducing cystine in keratin or hydrolyzed keratin. As long as keratin or cystine in hydrolyzed keratin can be reduced, the method and conditions for reduction are not particularly limited.

The origin of the keratin or hydrolyzed keratin for obtaining the reduced keratin is not limited. Specific examples of the keratin or hydrolyzed keratin include hair (human hair, wool, feathers, etc.), horns, and nails of humans and birds and animals containing keratin.

(C) The reduced keratin has no particular limitation on its specific structure as long as it has at least one thiol group. (C) The reduced keratin may be one in which all cystine in keratin is reduced by reduction, or one in which a part of cystine in keratin remains without being reduced. Further, (C) reduced keratin preferably has 4 or more cysteines per 100 amino acid residues from the viewpoint of cross-linking to hair. When the number of cysteines is 4 or more, the cross-linking force to the hair is strong and sufficient durability can be obtained, which is preferable. Furthermore, the molecular weight of (C) reduced keratin is not limited as long as it has protective power, repair power and modifying power with respect to the application site of hair.

(C) The content of reduced keratin can be appropriately set as needed. The content of (C) reduced keratin in the vesicle composition of the present invention is usually 0.01 to 20% by mass. The content may be combined with the above description of the content of the polyol (A). The contents of the above (A) polyol and (B) polyglycerin fatty acid ester and the blending ratios of the above (A) polyol and (B) polyglycerin fatty acid ester may be used alone or in combination, or in combination with all the descriptions.

The vesicle composition of the present invention may contain components other than the above (A) to (C), if necessary, as long as it does not inhibit vesicle formation.

The method for obtaining the vesicle composition of the present invention is not particularly limited. The vesicle composition of the present invention is, for example, by adding the components (A) to (C) individually to a solvent, or a liquid containing the components (A) and (B) and a liquid containing the component (C). By combining the above, a liquid material containing the components (A) to (C) is prepared, and then a known method such as stirring, specifically, for example, by stirring the liquid material at a high temperature with a homomixer. , Can be prepared. This description also discloses a method for vesicle-forming reduced keratin and a method for stabilizing reduced keratin.

Since the reduced keratin has a thiol group, the reduced keratin may react with each other and be crosslinked via the thiol group. When the reduced keratins are crosslinked with each other, the thiol group is lost, so that the reactivity of the reduced keratin is lowered. If the reduced keratin is in a single state, it can be stabilized by adding a solubilizer (surfactant or the like) or a stabilizer (reducing agent or the like). However, when reduced keratin is added to hair cosmetics, the reduced keratins may crosslink each other due to the interaction of a plurality of compounding components of the hair cosmetics.

In the vesicle composition of the present invention, the reduced keratin can be stabilized by converting the reduced keratin into a vesicle. Therefore, the vesicle composition of the present invention can prevent cross-linking between reduced keratins. Furthermore, even when the vesicled reduced keratin is blended in the hair cosmetics, it is possible to prevent cross-linking between the reduced keratins and stabilize the reduced keratins. Therefore, by incorporating the vesicle composition of the present invention into hair cosmetics, the useful effect of reduced keratin can be exhibited for a long period of time. It should be noted that the findings are for the convenience of understanding the invention only, and are not an explanation of the purpose of defining the present invention.

(2) Hair Cosmetics The hair cosmetics of the present invention include the vesicle composition of the present invention. The hair cosmetic of the present invention can improve the permeability to the application site of hair by vesicle-forming and stabilizing the reduced keratin. As a result, it is possible to enhance the protective power, the repair power, and the reforming power for the application site of the hair.

In the hair cosmetic of the present invention, the content of the vesicle composition of the present invention is not particularly limited as long as it is an effective amount for the function and characteristics at the application site of the hair.

The method for incorporating the vesicle composition of the present invention into the hair cosmetic of the present invention is not particularly limited. For example, the vesicle composition of the present invention may be prepared separately and added to hair cosmetics. In addition, the components (A) to (C) constituting the vesicle composition of the present invention are blended together with the components (or a part thereof) constituting the hair cosmetic, and are used in the hair cosmetic or the hair cosmetic. Vesicles may be formed in the constituents of the above.

The hair cosmetic of the present invention may contain other components other than the above (A) to (C), if necessary, as long as the action of the present invention is not impaired. Examples of the other component include known components conventionally added and contained in hair cosmetics, and other functional components. Specifically, as the other components, for example, fats and oils, hydrocarbon oils, higher fatty acids, higher alcohols, ester oils, silicone oils, surfactants (nonionic, anionic, cationic, amphoteric), moisturizing. Agents, water-soluble polymers, film agents, UV absorbers, metal ion blockers, lower alcohols, polyhydric alcohols, sugars, amino acids, pH adjusters, vitamins, antioxidants, pigments, preservatives, fragrances, etc. Be done.

The specific use of the hair cosmetic of the present invention is not particularly limited. The hair cosmetic of the present invention is, for example, for improving the physical characteristics (strength, elongation rate, etc.) of hair, improving the disorder of hair tips due to swelling or swelling of hair, or further texture (moist feeling, smoothness). It can be used to improve the feeling, softness, etc.). Since the hair cosmetic contains reduced keratin, specific embodiments include, for example, shampoo, conditioner, treatment, conditioner, hair styling product, permanent wave agent, curling agent, hair coloring agent, hair growth / hair restorer, and the like. And before or after using these agents, pretreatment agents and the like are preferable.

(3) Stabilizer The stabilizer for the reduced keratin of the present invention contains (A) a polyol and (B) a polyglycerin fatty acid ester. The above description is valid for (A) polyols and (B) polyglycerin fatty acid esters. Further, regarding "reduced keratin", the above description of (C) reduced keratin is appropriate.

The stabilizer of the present invention may contain components other than the above (A) and (B), if necessary, as long as it does not inhibit the vesicle formation of the reduced keratin.

The reduced keratin can be stabilized by combining the stabilizer of the present invention with the reduced keratin to vesicle the reduced keratin. This makes it possible to prevent cross-linking between reduced keratins. Even when the reduced keratin vesicled by this method is added to the hair cosmetics, it is possible to prevent cross-linking between the reduced keratins, stabilize the reduced keratins, and exert a long-term useful effect.

The method and conditions for stabilizing the reduced keratin or vesicle the reduced keratin with the stabilizer of the present invention are not particularly limited. For example, a liquid material is prepared by combining the stabilizer of the present invention and a liquid containing reduced keratin, and then a known method such as stirring, specifically, for example, stirring the liquid material at a high temperature with a homomixer. By doing so, the reduced keratin can be vesicled and the reduced keratin can be stabilized. The liquid material may contain components other than the stabilizer and reduced keratin of the present invention, if necessary.

Hereinafter, the present invention will be specifically described with reference to Examples. The present invention is not limited to the embodiment shown in the examples. The embodiments of the present invention can be variously modified within the scope of the present invention according to the purpose and use. It should be added that all the considerations for the results in the examples are merely the views of the inventor and do not explain the purpose of defining the present invention.

(1) Preparation of vesicle composition The vesicle compositions of Examples 1 to 3 and Comparative Examples 1 to 4 shown in Table 1 were prepared according to a conventional method. The numerical values in Table 1 indicate the content of the components in the column, and the unit thereof is mass%.

(2) Time-dependent stability test of reduced keratin The vesicle compositions of Examples 1 to 3 and Comparative Examples 1 to 4 prepared in (1) above were placed in an incubator set at 50 ° C. After being left in the incubator DKN302 ") for 14 days, the stability was evaluated. The results are shown in Table 1. The stability here is the stability of reduced keratin. When the reduced keratins react with each other to crosslink the reduced keratins, the solubility is lowered and starch is generated. Here, the stability of the generation of starch was evaluated on a 5-point scale. The more starch there is, the less stable it is.
・ Stability evaluation 5: No starch is generated 4: Almost no starch is generated 3: Slightly starch is generated 2: Star is generated 1: Many starch is generated

(3) Test Results From the results in Table 1, it was confirmed that the reduced keratin was superior in stability over time in Examples 1 to 3 contained in the vesicle composition of the present invention as compared with Comparative Examples 1 to 4.

An example of prescribing a hair cosmetic containing the vesicle composition of the present invention is shown below. The blending amount is mass%. In all of these prescription examples, excellent stability of reduced keratin was confirmed by the evaluation method of (2) above.

(Prescription example 1; shampoo)
Ingredient content (% by mass)
Cocoyl Glutamic Acid TEA 12.00
Lauroylmethylalanine Na 4.00
Cocamidopropyl Betaine 3.00
Cocamide DEA 1.50
Polyquaternium-10 0.40
Urea 1.00
Etidronic acid 0.05
Na benzoate 0.40
Composition of Example 2 10.00
Rooibos extract 0.10
Aloe vera juice 0.10
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 2; Hair treatment)
Ingredient content (% by mass)
Behentrimonium chloride 1.50
Stealtrimonium chloride 1.50
Glyceryl stearate 1.00
Cetyl alcohol 6.00
Behenyl alcohol 1.00
Hydrogenated polyisobutene 6.00
Dimethicone 3.00
Amodimethicone 1.00
Dimethiconol 1.00
Polysilicone-29 0.30
Cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol 0.20
Glycerin 1.00
BG 2.00
Caesar Pinia Spinosa Gum 0.40
Lactic acid 0.05
Cholesterol 0.10
Ceramide NP 0.10
Methylparaben 0.20
Propylparaben 0.10
Composition of Example 2 10.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 3; Hair mist)
Ingredient content (% by mass)
PEG-60 hydrogenated castor oil 1.00
BG 5.00
Glycerin 2.00
Ethoxydiglycol 1.00
Urea 1.00
Citric acid 0.05
Dimethicone 0.50
Amodimethicone 0.50
Viscetealylamodimethicone 0.50
Dimethiconol 0.50
Ceramide AG 0.10
Hydrolyzed silk 0.50
Arginine Ethyl HCl 0.50
Blackcurrant fruit extract 0.01
Methylparaben 0.20
Composition of Example 2 10.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 4; treatment agent)
Ingredient content (% by mass)
PG 5.00
Glycerin 2.00
Betaine 2.00
Urea 1.00
Trehalose 0.50
Polyquaternium-7 0.50
Decyl glucoside 0.10
Lauramide Propyl Betaine 0.10
Hydrolyzed keratin 1.00
Hydrolyzed collagen 1.00
Hydrolyzed silk 1.00
Ceramide AP 0.50
Arginine 0.01
Citric acid 0.05
Methylparaben 0.20
Composition of Example 2 5.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 5; hair wax)
Ingredient content (% by mass)
Candelilla Row 3.00
Cetearyl alcohol 2.00
Glyceryl stearate 1.00
Stearic acid 2.00
Setes-40 1.00
Hydrogenated polyisobutene 4.00
Dimethicone 2.00
Polyacrylamide 0.50
BG 2.00
Na hydroxide 0.02
Jojoba seed oil 0.10
Phenoxyethanol 0.80
Composition of Example 2 2.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 6; Hair cream)
Ingredient content (% by mass)
Mineral oil 10.00
Grape seed oil 3.00
Vaseline 3.00
Glyceryl isostearate 2.00
Setes-40 2.00
Camellia seed extract 0.50
Polysorbate-20 1.00
Carbomer 0.50
Arginine 0.10
Glycerin 3.00
Methylparaben 0.20
Propylparaben 0.10
Composition of Example 2 4.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 7; Hair manicure)
Ingredient content (% by mass)
Benzyl alcohol 4.00
Ethanol 25.00
Glycolic acid 2.00
Hydroxyethyl cellulose 2.00
Xanthan gum 0.40
Dimethicone 1.00
Black 401 0.50
Composition of Example 2 3.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 8; Hair color treatment)
Ingredient content (% by mass)
Stealtrimonium chloride 1.00
Behenamide propyldimethylamine 2.00
Cetearyl alcohol 8.00
Glyceryl caprylate 2.00
Decyl glucoside 0.50
Hydroxyethyl cellulose 0.30
Polyquaternium-37 0.50
Dimethicone 1.00
Amodimethicone 1.00
Dimethiconol 1.00
Ethoxydiglycol 3.00
Glyceryl glucoside 1.00
Urea 4.00
Ammonium bicarbonate 0.80
Arginine 0.40
Basic blue 9 90.20
HC Blue 2 0.20
Composition of Example 2 5.00
Phenoxyethanol 0.80
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription example 9; curling agent)
(1 agent)
Ingredient content (% by mass)
Cysteamine HCl 2.00
Cholesterol 0.50
Glucosyl ceramide 0.50
Monoethanolamine 0.50
Arginine 0.30
Citric acid 0.50
Polyglyceryl stearate-10 1.00
Cocamide DEA 1.00
EDTA-2Na 0.10
Phenoxyethanol 0.80
Composition of Example 2 2.00
Appropriate amount of fragrance Remaining amount of purified water
Total amount 100.00
(2 agents)
Ingredient content (% by mass)
Na bromate 10.00
BG 4.00
Citric acid 0.10
Na citrate 0.60
Phenoxyethanol 0.80
Hydroxyethyl cellulose 2.00
PEG-60 hydrogenated castor oil 1.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

(Prescription Example 10; Hairspray (aerosol))
Ingredient content (% by mass)
(Alkyl acrylate / Diacetone acrylamide) Copolymer AMP 2.00
BG 1.00
Yuzu fruit extract 1.00
Dimethicone 0.10
Composition of Example 2 1.00
Purified water 5.00
Perfume Appropriate amount Ethanol Remaining amount LPG 6.00
Total amount 100.00

(Prescription example 11; set gel)
Ingredient content (% by mass)
PVP 4.00
BG 2.00
Ethanol 25.00
Guar hydroxypropyltrimonium chloride 1.20
Citric acid 0.05
Na citrate 0.10
Arge extract 1.00
Macademia nut oil 0.10
Composition of Example 2 1.00
Perfume Appropriate amount Purified water remaining amount
Total amount 100.00

As mentioned above, the compositions and stabilizers of the present invention are excellent in stabilizing reduced keratin. Since the cosmetic for hair of the present invention is excellent in the stability of reduced keratin, it is excellent in protective power, repair power and improvement power at the application site of hair, and can exhibit a long-term useful effect. Therefore, the hair cosmetic of the present invention has a wide range of uses and is practical, and has high utility value in the field of the cosmetics industry.

Claims (3)

A vesicle composition containing (A) a polyol, (B) a polyglycerin fatty acid ester, and (C) a reduced keratin. A cosmetic for hair containing the vesicle composition according to claim 1. A stabilizer for reduced keratin containing (A) a polyol and (B) a polyglycerin fatty acid ester.