JP2020535436A5 - - Google Patents

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Publication number
JP2020535436A5
JP2020535436A5 JP2020518048A JP2020518048A JP2020535436A5 JP 2020535436 A5 JP2020535436 A5 JP 2020535436A5 JP 2020518048 A JP2020518048 A JP 2020518048A JP 2020518048 A JP2020518048 A JP 2020518048A JP 2020535436 A5 JP2020535436 A5 JP 2020535436A5
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JP
Japan
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fgf
treatment
subject
2sdng
compound
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JP2020518048A
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English (en)
Japanese (ja)
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JP2020535436A (ja
JP7791649B2 (ja
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Priority claimed from PCT/EP2018/076395 external-priority patent/WO2019063758A1/en
Publication of JP2020535436A publication Critical patent/JP2020535436A/ja
Publication of JP2020535436A5 publication Critical patent/JP2020535436A5/ja
Priority to JP2024064931A priority Critical patent/JP2024105273A/ja
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Publication of JP7791649B2 publication Critical patent/JP7791649B2/ja
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JP2020518048A 2017-09-29 2018-09-28 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー Active JP7791649B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024064931A JP2024105273A (ja) 2017-09-29 2024-04-12 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17194220.4 2017-09-29
EP17194220 2017-09-29
EP18169324 2018-04-25
EP18169324.3 2018-04-25
PCT/EP2018/076395 WO2019063758A1 (en) 2017-09-29 2018-09-28 METABOLIC BIOMARKERS FOR PREDICTING RESPONSE TO FGF-18 COMPOUND

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024064931A Division JP2024105273A (ja) 2017-09-29 2024-04-12 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー

Publications (3)

Publication Number Publication Date
JP2020535436A JP2020535436A (ja) 2020-12-03
JP2020535436A5 true JP2020535436A5 (https=) 2021-11-11
JP7791649B2 JP7791649B2 (ja) 2025-12-24

Family

ID=63722380

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020518048A Active JP7791649B2 (ja) 2017-09-29 2018-09-28 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー
JP2024064931A Withdrawn JP2024105273A (ja) 2017-09-29 2024-04-12 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024064931A Withdrawn JP2024105273A (ja) 2017-09-29 2024-04-12 Fgf-18化合物に対する反応性を予測する代謝バイオマーカー

Country Status (16)

Country Link
US (2) US11513128B2 (https=)
EP (1) EP3687558B1 (https=)
JP (2) JP7791649B2 (https=)
CN (1) CN111163791A (https=)
AU (1) AU2018343982B2 (https=)
CA (1) CA3076029A1 (https=)
DK (1) DK3687558T3 (https=)
ES (1) ES2918250T3 (https=)
HR (1) HRP20220760T1 (https=)
HU (1) HUE058786T2 (https=)
IL (1) IL273613B2 (https=)
LT (1) LT3687558T (https=)
PL (1) PL3687558T3 (https=)
RS (1) RS63293B1 (https=)
SI (1) SI3687558T1 (https=)
WO (1) WO2019063758A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016211950A1 (en) 2015-01-29 2017-07-13 Ares Trading S.A. Immunoassays for high positively charged proteins
IL273613B2 (en) 2017-09-29 2026-02-01 Merck Patent Gmbh Metabolic biomarkers for predicting response to FGF-18 compound
SI3688468T1 (sl) 2017-09-29 2022-08-31 Merck Patent Gmbh Vnetni biomarkerji za predvidevanje odzivov na spojino FGF-18
IL281333B2 (en) 2018-09-10 2025-11-01 Merck Patent Gmbh A method for reducing risk in a clinical trial

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2339002A1 (en) 1996-10-16 2011-06-29 ZymoGenetics, Inc. Fibroblast growth factor homologs
ES2493840T3 (es) 2002-10-07 2014-09-12 Zymogenetics, Inc. Procedimiento de administración de FGF-18
AU2003287697A1 (en) 2002-11-08 2004-06-03 Barnes-Jewish Hospital Uncoupled collagen synthesis and degradation assays
AU2005314438B2 (en) 2004-12-10 2012-03-29 Zymogenetics, Inc. FGF18 production in prokaryotic hosts
US8224579B2 (en) * 2005-06-17 2012-07-17 The Brigham And Women's Hospital, Inc. Method of diagnosing osteoarthritis
US20070292982A1 (en) 2006-06-16 2007-12-20 Jeffery Gail Holloway Method for Manufacturing Transparent Windows in Molded Semiconductor Packages
HRP20120643T1 (hr) 2006-08-25 2012-08-31 Ares Trading S.A. Liječenje poremećaja hrskavice sa fgf-18
JP2009257842A (ja) 2008-04-14 2009-11-05 Ttc:Kk 変形性関節症の検査方法及び診断用キット
JP5762282B2 (ja) 2008-05-02 2015-08-12 インタールーキン ジェネティクス, インコーポレイテッド 変形性関節症に関連する状態に対する遺伝的素因の検出
US20090299769A1 (en) 2008-05-29 2009-12-03 Nordic Bioscience Imaging A/S Prognostic osteoarthritis biomarkers
US20120115137A1 (en) 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
TWI527590B (zh) 2011-06-17 2016-04-01 艾瑞斯貿易公司 Fgf-18之凍乾調配物
AU2013301607B2 (en) 2012-08-06 2018-10-18 Merck Patent Gmbh Prognosis biomarkers in cartilage disorders
CN104736723B (zh) * 2012-08-06 2017-10-31 默克专利有限公司 用于预测对fgf‑18化合物的响应性的遗传标记
US9829493B2 (en) * 2013-07-15 2017-11-28 Steven J. Svoboda Methods and apparatus for assessment of risk for joint injury
CA2931978A1 (en) 2013-12-02 2015-06-11 Abbvie Inc. Compositions and methods for treating osteoarthritis
ES2806026T3 (es) 2013-12-24 2021-02-16 Ares Trading Sa Formulación de FGF-18 en hidrogeles de alginato/colágeno
KR102622290B1 (ko) 2013-12-24 2024-01-05 아레스 트레이딩 에스.아. 크실로글루칸 겔 중의 fgf-18 제형물
HUE040350T2 (hu) 2014-02-20 2019-03-28 Merck Patent Gmbh FGF-18 vegyületadagoló étrend
MX2016010873A (es) 2014-02-20 2016-11-17 Merck Patent Gmbh Factor de crecimiento de fibroblastos 18 en los procedimientos para el trasplante de injertos y para ingenieria de tejidos.
JP6510547B2 (ja) 2014-02-20 2019-05-08 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung Fgf−18を含むインプラント
AU2016211950A1 (en) 2015-01-29 2017-07-13 Ares Trading S.A. Immunoassays for high positively charged proteins
MX380092B (es) 2015-11-06 2025-03-11 Samumed Llc Tratamiento de la osteoartritis.
US9983214B2 (en) 2016-04-15 2018-05-29 Esm Technologies, Llc Method for evaluating articular joint therapeutics
SI3688468T1 (sl) 2017-09-29 2022-08-31 Merck Patent Gmbh Vnetni biomarkerji za predvidevanje odzivov na spojino FGF-18
IL273613B2 (en) * 2017-09-29 2026-02-01 Merck Patent Gmbh Metabolic biomarkers for predicting response to FGF-18 compound
IL281333B2 (en) 2018-09-10 2025-11-01 Merck Patent Gmbh A method for reducing risk in a clinical trial

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