JP2020530765A - リサウイルス抗原構築物 - Google Patents

リサウイルス抗原構築物 Download PDF

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Publication number
JP2020530765A
JP2020530765A JP2020502118A JP2020502118A JP2020530765A JP 2020530765 A JP2020530765 A JP 2020530765A JP 2020502118 A JP2020502118 A JP 2020502118A JP 2020502118 A JP2020502118 A JP 2020502118A JP 2020530765 A JP2020530765 A JP 2020530765A
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saturated
hydrocarbon chain
composition
rna
seq
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JP2020502118A
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Japanese (ja)
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JP2020530765A5 (enExample
Inventor
ヘイシー，キャスリン
マルヤラ，パドマ
サムサ，マルセロ
スラック，オルガ
ユー，ドン
ストークス，アラン
ジャラー，ラシュミ
Original Assignee
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム
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Publication of JP2020530765A publication Critical patent/JP2020530765A/ja
Publication of JP2020530765A5 publication Critical patent/JP2020530765A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2020502118A 2017-07-17 2018-07-16 リサウイルス抗原構築物 Pending JP2020530765A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762533312P 2017-07-17 2017-07-17
US62/533,312 2017-07-17
PCT/IB2018/055258 WO2019016680A1 (en) 2017-07-17 2018-07-16 ANTIGEN CONSTRUCTS OF LYSSAVIRUS

Publications (2)

Publication Number Publication Date
JP2020530765A true JP2020530765A (ja) 2020-10-29
JP2020530765A5 JP2020530765A5 (enExample) 2022-05-25

Family

ID=63364109

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020502118A Pending JP2020530765A (ja) 2017-07-17 2018-07-16 リサウイルス抗原構築物

Country Status (7)

Country Link
US (2) US11278613B2 (enExample)
EP (1) EP3655536A1 (enExample)
JP (1) JP2020530765A (enExample)
CN (1) CN111108203A (enExample)
BR (1) BR112020000802A2 (enExample)
CA (1) CA3070042A1 (enExample)
WO (1) WO2019016680A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022244815A1 (ja) * 2021-05-19 2022-11-24 第一三共株式会社 Ｈｐｖ感染症ワクチン
JP2024507482A (ja) * 2021-02-05 2024-02-20 イモーナ（ハンチョウ）バイオテクノロジー カンパニー リミテッド イオン化可能な脂質分子、その製造方法及び脂質ナノ粒子の製造における応用

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269933A (zh) * 2019-07-17 2019-09-24 苏州世诺生物技术有限公司 一种狂犬病毒亚单位疫苗的制备方法及其应用
CN110643632B (zh) * 2019-09-26 2022-06-10 中国科学院武汉病毒研究所 一种基于甲病毒复制子载体的狂犬病毒感染性克隆及制备方法和应用
WO2022077330A1 (zh) * 2020-10-15 2022-04-21 中国科学院深圳先进技术研究院 一种新型g基因及其在高效逆向跨单突触中的应用
AU2022208435A1 (en) 2021-01-18 2023-08-10 Conserv Bioscience Limited Coronavirus immunogenic compositions, methods and uses thereof
EP4396342A1 (en) 2021-09-01 2024-07-10 GlaxoSmithKline Biologicals S.A. Plasmid dna purification methods
CN117460827A (zh) * 2022-02-09 2024-01-26 苏州艾博生物科技有限公司 狂犬病核酸疫苗
CN116120198B (zh) * 2022-03-21 2024-03-15 苏州科锐迈德生物医药科技有限公司 具有甘油骨架的脂质化合物及基于其的脂质载体、核酸脂质纳米粒组合物和药物制剂
CN116063410B (zh) * 2022-10-20 2023-07-14 北京标驰泽惠生物科技有限公司 一种狂犬病毒g蛋白的突变体及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010523086A (ja) * 2007-03-30 2010-07-15 ザ・リサーチ・ファウンデーション・オブ・ステート・ユニヴァーシティー・オブ・ニュー・ヨーク ワクチンに有用な弱毒化ウイルス
WO2015024665A1 (en) * 2013-08-21 2015-02-26 Curevac Gmbh Rabies vaccine
WO2016037053A1 (en) * 2014-09-05 2016-03-10 Novartis Ag Lipids and lipid compositions for the delivery of active agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10426737B2 (en) 2013-12-19 2019-10-01 Novartis Ag Lipids and lipid compositions for the delivery of active agents
US10059655B2 (en) 2013-12-19 2018-08-28 Novartis Ag Lipids and lipid compositions for the delivery of active agents
JP7118062B2 (ja) 2016-12-09 2022-08-15 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム リサウイルス抗原を有するチンパンジーアデノウイルス構築物
GB201620968D0 (en) * 2016-12-09 2017-01-25 Glaxosmithkline Biologicals Sa Adenovirus polynucleotides and polypeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010523086A (ja) * 2007-03-30 2010-07-15 ザ・リサーチ・ファウンデーション・オブ・ステート・ユニヴァーシティー・オブ・ニュー・ヨーク ワクチンに有用な弱毒化ウイルス
WO2015024665A1 (en) * 2013-08-21 2015-02-26 Curevac Gmbh Rabies vaccine
WO2016037053A1 (en) * 2014-09-05 2016-03-10 Novartis Ag Lipids and lipid compositions for the delivery of active agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ADVANCES IN GENETICS, vol. Vol.89, pp.179-233, JPN6022022341, 2015, ISSN: 0005080506 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024507482A (ja) * 2021-02-05 2024-02-20 イモーナ（ハンチョウ）バイオテクノロジー カンパニー リミテッド イオン化可能な脂質分子、その製造方法及び脂質ナノ粒子の製造における応用
JP7683017B2 (ja) 2021-02-05 2025-05-26 イモーナ（ハンチョウ）バイオテクノロジー カンパニー リミテッド イオン化可能な脂質分子、その製造方法及び脂質ナノ粒子の製造における応用
WO2022244815A1 (ja) * 2021-05-19 2022-11-24 第一三共株式会社 Ｈｐｖ感染症ワクチン
JPWO2022244815A1 (enExample) * 2021-05-19 2022-11-24

Also Published As

Publication number Publication date
EP3655536A1 (en) 2020-05-27
US11278613B2 (en) 2022-03-22
BR112020000802A2 (pt) 2020-07-21
US20200222526A1 (en) 2020-07-16
WO2019016680A1 (en) 2019-01-24
CN111108203A (zh) 2020-05-05
US20220241398A1 (en) 2022-08-04
CA3070042A1 (en) 2019-01-24

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