JP2020527545A5 - - Google Patents
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- Publication number
- JP2020527545A5 JP2020527545A5 JP2019572658A JP2019572658A JP2020527545A5 JP 2020527545 A5 JP2020527545 A5 JP 2020527545A5 JP 2019572658 A JP2019572658 A JP 2019572658A JP 2019572658 A JP2019572658 A JP 2019572658A JP 2020527545 A5 JP2020527545 A5 JP 2020527545A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- therapeutic agent
- coating
- nanoparticles according
- magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002105 nanoparticle Substances 0.000 claims 25
- 239000003814 drug Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 229940124597 therapeutic agent Drugs 0.000 claims 9
- 239000011248 coating agent Substances 0.000 claims 7
- 238000000576 coating method Methods 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 239000002122 magnetic nanoparticle Substances 0.000 claims 3
- 239000012190 activator Substances 0.000 claims 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims 2
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical group [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 230000004071 biological effect Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229960003405 ciprofloxacin Drugs 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960001347 fluocinolone acetonide Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical group C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023204132A JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762527274P | 2017-06-30 | 2017-06-30 | |
| US62/527,274 | 2017-06-30 | ||
| PCT/US2018/040523 WO2019006440A1 (en) | 2017-06-30 | 2018-06-30 | MAGNETIC NANOPARTICLES FOR TARGETED ADMINISTRATION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204132A Division JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020527545A JP2020527545A (ja) | 2020-09-10 |
| JP2020527545A5 true JP2020527545A5 (https=) | 2021-09-09 |
Family
ID=64742731
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572658A Pending JP2020527545A (ja) | 2017-06-30 | 2018-06-30 | 標的化送達のための磁性ナノ粒子 |
| JP2023204132A Pending JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204132A Pending JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200146995A1 (https=) |
| EP (1) | EP3645004A4 (https=) |
| JP (2) | JP2020527545A (https=) |
| CN (1) | CN111032023A (https=) |
| AU (1) | AU2018291045A1 (https=) |
| BR (1) | BR112020003956A2 (https=) |
| CA (1) | CA3069671A1 (https=) |
| WO (1) | WO2019006440A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4048290A4 (en) * | 2019-10-22 | 2023-12-06 | Otomagnetics, Inc. | LIPID-COATED IRON OXIDE NANOPARTICLES FOR OTITIS MEDIUM |
| EP4054695A4 (en) * | 2019-11-05 | 2024-01-03 | Bionaut Labs Ltd. | SYSTEM AND MINIATURE DEVICES FOR THE ADMINISTRATION OF A THERAPEUTIC CONSTITUENT AT A TREATMENT SITE IN A PATIENT |
| WO2021160873A1 (en) * | 2020-02-13 | 2021-08-19 | Eth Zurich | Nanoparticles encapsulating small molecules |
| AU2021403179A1 (en) | 2020-12-15 | 2023-08-03 | Otomagnetics, Inc. | Medical cart for magnetic treatment of middle ear conditions |
| JP7820409B2 (ja) * | 2021-04-30 | 2026-02-25 | サムヤン ホールディングス コーポレイション | 両親媒性高分子を含まないナノ粒子を含む薬物送達用組成物 |
| WO2022236264A1 (en) | 2021-05-04 | 2022-11-10 | Otomagnetics, Inc. | Methods for shaping magnetics fields to align forces on magnetic particles for patient anatomy and motion |
| CN115837078A (zh) * | 2022-12-27 | 2023-03-24 | 西安超磁纳米生物科技有限公司 | 一种聚合物修饰的无机纳米材料冻干粉、制备方法及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002087586A1 (en) * | 2001-04-26 | 2002-11-07 | Control Delivery Systems, Inc. | Sustained release drug delivery system containing codrugs |
| AU2004231992B2 (en) * | 2003-04-16 | 2011-04-21 | Drexel University | Magnetically controllable drug and gene delivery stents |
| KR100612734B1 (ko) * | 2003-04-30 | 2006-08-18 | 함승주 | 자기성 물질 및 치료제를 생분해성 고분자로 캡슐화한자기성 나노입자를 함유하는 조성물 |
| CA2523035C (en) * | 2003-05-22 | 2011-04-26 | Elan Pharma International Ltd. | Sterilization of dispersions of nanoparticulate active agents with gamma radiation |
| US20060204442A1 (en) * | 2003-09-12 | 2006-09-14 | Bankruptcy Estate Of Ferx, Inc. | Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents |
| US8562505B2 (en) * | 2004-02-20 | 2013-10-22 | The Children's Hospital Of Philadelphia | Uniform field magnetization and targeting of therapeutic formulations |
| US9028829B2 (en) * | 2004-02-20 | 2015-05-12 | The Children's Hospital Of Philadelphia | Uniform field magnetization and targeting of therapeutic formulations |
| KR101306641B1 (ko) * | 2005-03-21 | 2013-09-12 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 작용화된 자성 나노입자 및 이의 사용방법 |
| US20070264199A1 (en) * | 2005-09-26 | 2007-11-15 | Labhasetwar Vinod D | Magnetic nanoparticle composition and methods for using the same |
| US8357401B2 (en) * | 2009-12-11 | 2013-01-22 | Bind Biosciences, Inc. | Stable formulations for lyophilizing therapeutic particles |
| CA2801535C (en) * | 2010-06-04 | 2017-05-30 | Hough Ear Institute | Composition and method for inner ear sensory hair cell regeneration or replacement |
| US20150125401A1 (en) * | 2012-04-20 | 2015-05-07 | Board Of The Regents Of The University Of Nebraska | Small magnetite therapeutics and methods of use thereof |
| US20160346389A1 (en) * | 2013-09-12 | 2016-12-01 | Albert Einstein College Of Medicine Inc. | Modified paramagnetic nanoparticles for targeted delivery of therapeutics and methods thereof |
| WO2016004043A1 (en) * | 2014-06-30 | 2016-01-07 | Blend Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
| CN105434399B (zh) * | 2015-12-24 | 2018-03-06 | 湖南尔康制药股份有限公司 | 一种肾细胞癌治疗药物舒尼替尼‑PLGA/Fe3O4复合微球及其制备方法 |
-
2018
- 2018-06-30 WO PCT/US2018/040523 patent/WO2019006440A1/en not_active Ceased
- 2018-06-30 JP JP2019572658A patent/JP2020527545A/ja active Pending
- 2018-06-30 CN CN201880054293.8A patent/CN111032023A/zh active Pending
- 2018-06-30 AU AU2018291045A patent/AU2018291045A1/en not_active Abandoned
- 2018-06-30 BR BR112020003956-0A patent/BR112020003956A2/pt not_active Application Discontinuation
- 2018-06-30 CA CA3069671A patent/CA3069671A1/en active Pending
- 2018-06-30 EP EP18824766.2A patent/EP3645004A4/en not_active Withdrawn
- 2018-06-30 US US16/627,677 patent/US20200146995A1/en not_active Abandoned
-
2023
- 2023-12-01 JP JP2023204132A patent/JP2024028827A/ja active Pending
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