JP2020527545A5 - - Google Patents
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- Publication number
- JP2020527545A5 JP2020527545A5 JP2019572658A JP2019572658A JP2020527545A5 JP 2020527545 A5 JP2020527545 A5 JP 2020527545A5 JP 2019572658 A JP2019572658 A JP 2019572658A JP 2019572658 A JP2019572658 A JP 2019572658A JP 2020527545 A5 JP2020527545 A5 JP 2020527545A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- therapeutic agent
- coating
- nanoparticles according
- magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002105 nanoparticle Substances 0.000 claims 25
- 239000003814 drug Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 229940124597 therapeutic agent Drugs 0.000 claims 9
- 239000011248 coating agent Substances 0.000 claims 7
- 238000000576 coating method Methods 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 239000002122 magnetic nanoparticle Substances 0.000 claims 3
- 239000012190 activator Substances 0.000 claims 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims 2
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical group [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 230000004071 biological effect Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229960003405 ciprofloxacin Drugs 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960001347 fluocinolone acetonide Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical group C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023204132A JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762527274P | 2017-06-30 | 2017-06-30 | |
| US62/527,274 | 2017-06-30 | ||
| PCT/US2018/040523 WO2019006440A1 (en) | 2017-06-30 | 2018-06-30 | MAGNETIC NANOPARTICLES FOR TARGETED ADMINISTRATION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204132A Division JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020527545A JP2020527545A (ja) | 2020-09-10 |
| JP2020527545A5 true JP2020527545A5 (https=) | 2021-09-09 |
Family
ID=64742731
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572658A Pending JP2020527545A (ja) | 2017-06-30 | 2018-06-30 | 標的化送達のための磁性ナノ粒子 |
| JP2023204132A Pending JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204132A Pending JP2024028827A (ja) | 2017-06-30 | 2023-12-01 | 標的化送達のための磁性ナノ粒子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200146995A1 (https=) |
| EP (1) | EP3645004A4 (https=) |
| JP (2) | JP2020527545A (https=) |
| CN (1) | CN111032023A (https=) |
| AU (1) | AU2018291045A1 (https=) |
| BR (1) | BR112020003956A2 (https=) |
| CA (1) | CA3069671A1 (https=) |
| WO (1) | WO2019006440A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3155347A1 (en) * | 2019-10-22 | 2021-04-29 | Benjamin Shapiro | Lipid coated iron oxide nanoparticles for otitis media |
| US20220409871A1 (en) * | 2019-11-05 | 2022-12-29 | Bionaut Labs Ltd | System and miniature devices for delivering a therapeutic component to a treatment site in a patient |
| CN115379831A (zh) * | 2020-02-13 | 2022-11-22 | 苏黎世联邦理工学院 | 包封小分子的纳米颗粒 |
| WO2022133459A1 (en) | 2020-12-15 | 2022-06-23 | Otomagnetics, Inc. | Medical cart for magnetic treatment of middle ear conditions |
| EP4331576A4 (en) * | 2021-04-30 | 2025-06-11 | Samyang Holdings Corporation | COMPOSITION FOR THE ADMINISTRATION OF A MEDICAMENT COMPRISING NANOPARTICLES NOT CONTAINING AN AMPHIPHILIC POLYMER |
| JP2024517868A (ja) | 2021-05-04 | 2024-04-23 | オトマグネティクス，インコーポレイテッド | 患者の解剖学的構造および動作のために磁性粒子にかかる力を調整する磁場を形作る方法 |
| CN115837078A (zh) * | 2022-12-27 | 2023-03-24 | 西安超磁纳米生物科技有限公司 | 一种聚合物修饰的无机纳米材料冻干粉、制备方法及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ528994A (en) * | 2001-04-26 | 2006-02-24 | Control Delivery Sys Inc | Sustained release drug delivery system containing codrugs |
| CA2821376A1 (en) * | 2003-04-16 | 2004-11-04 | The Children's Hospital Of Philadelphia | Magnetically controllable drug and gene delivery stents |
| KR100612734B1 (ko) * | 2003-04-30 | 2006-08-18 | 함승주 | 자기성 물질 및 치료제를 생분해성 고분자로 캡슐화한자기성 나노입자를 함유하는 조성물 |
| EP1626742A1 (en) * | 2003-05-22 | 2006-02-22 | Elan Pharma International Limited | Sterilization of dispersions of nanoparticulate active agents with gamma radiation |
| CN1879065A (zh) * | 2003-09-12 | 2006-12-13 | 弗尔克斯破产财产公司 | 用于生物活性剂的定位传递的包含磁性成分和生物相容性聚合物的可磁靶向颗粒 |
| US9028829B2 (en) * | 2004-02-20 | 2015-05-12 | The Children's Hospital Of Philadelphia | Uniform field magnetization and targeting of therapeutic formulations |
| US8562505B2 (en) * | 2004-02-20 | 2013-10-22 | The Children's Hospital Of Philadelphia | Uniform field magnetization and targeting of therapeutic formulations |
| CA2923748C (en) * | 2005-03-21 | 2017-06-20 | The Regents Of The University Of California | Functionalized magnetic nanoparticles and methods of use thereof |
| US20070264199A1 (en) * | 2005-09-26 | 2007-11-15 | Labhasetwar Vinod D | Magnetic nanoparticle composition and methods for using the same |
| DK2509634T3 (en) * | 2009-12-11 | 2019-04-23 | Pfizer | Stable formulations for lyophilization of therapeutic particles |
| CA2801535C (en) * | 2010-06-04 | 2017-05-30 | Hough Ear Institute | Composition and method for inner ear sensory hair cell regeneration or replacement |
| US20150125401A1 (en) * | 2012-04-20 | 2015-05-07 | Board Of The Regents Of The University Of Nebraska | Small magnetite therapeutics and methods of use thereof |
| WO2015038924A1 (en) * | 2013-09-12 | 2015-03-19 | Albert Einstein College Of Medicine Of Yeshiva University | Modified paramagnetic nanoparticles for targeted delivery of therapeutics and methods thereof |
| WO2016004043A1 (en) * | 2014-06-30 | 2016-01-07 | Blend Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
| CN105434399B (zh) * | 2015-12-24 | 2018-03-06 | 湖南尔康制药股份有限公司 | 一种肾细胞癌治疗药物舒尼替尼‑PLGA/Fe3O4复合微球及其制备方法 |
-
2018
- 2018-06-30 WO PCT/US2018/040523 patent/WO2019006440A1/en not_active Ceased
- 2018-06-30 CA CA3069671A patent/CA3069671A1/en active Pending
- 2018-06-30 JP JP2019572658A patent/JP2020527545A/ja active Pending
- 2018-06-30 EP EP18824766.2A patent/EP3645004A4/en not_active Withdrawn
- 2018-06-30 US US16/627,677 patent/US20200146995A1/en not_active Abandoned
- 2018-06-30 CN CN201880054293.8A patent/CN111032023A/zh active Pending
- 2018-06-30 BR BR112020003956-0A patent/BR112020003956A2/pt not_active Application Discontinuation
- 2018-06-30 AU AU2018291045A patent/AU2018291045A1/en not_active Abandoned
-
2023
- 2023-12-01 JP JP2023204132A patent/JP2024028827A/ja active Pending
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