JP2020522544A5 - - Google Patents

Download PDF

Info

Publication number
JP2020522544A5
JP2020522544A5 JP2019567608A JP2019567608A JP2020522544A5 JP 2020522544 A5 JP2020522544 A5 JP 2020522544A5 JP 2019567608 A JP2019567608 A JP 2019567608A JP 2019567608 A JP2019567608 A JP 2019567608A JP 2020522544 A5 JP2020522544 A5 JP 2020522544A5
Authority
JP
Japan
Prior art keywords
patient
pharmaceutical composition
antigen
antibody
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019567608A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020522544A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2018/054182 external-priority patent/WO2018225041A1/en
Publication of JP2020522544A publication Critical patent/JP2020522544A/ja
Publication of JP2020522544A5 publication Critical patent/JP2020522544A5/ja
Priority to JP2023111915A priority Critical patent/JP2023123842A/ja
Pending legal-status Critical Current

Links

JP2019567608A 2017-06-09 2018-06-09 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法 Pending JP2020522544A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023111915A JP2023123842A (ja) 2017-06-09 2023-07-07 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762517672P 2017-06-09 2017-06-09
US62/517,672 2017-06-09
US201762532162P 2017-07-13 2017-07-13
US62/532,162 2017-07-13
EP18305565 2018-05-04
EP18305565.6 2018-05-04
PCT/IB2018/054182 WO2018225041A1 (en) 2017-06-09 2018-06-09 Methods for treating hyperlipidemia in diabetic patients by administering a pcsk9 inhibitor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023111915A Division JP2023123842A (ja) 2017-06-09 2023-07-07 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法

Publications (2)

Publication Number Publication Date
JP2020522544A JP2020522544A (ja) 2020-07-30
JP2020522544A5 true JP2020522544A5 (https=) 2021-07-26

Family

ID=62815099

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019567608A Pending JP2020522544A (ja) 2017-06-09 2018-06-09 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法
JP2023111915A Pending JP2023123842A (ja) 2017-06-09 2023-07-07 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023111915A Pending JP2023123842A (ja) 2017-06-09 2023-07-07 Pcsk9阻害剤の投与による糖尿病患者における高脂血症を治療する方法

Country Status (9)

Country Link
EP (1) EP3634469A1 (https=)
JP (2) JP2020522544A (https=)
KR (1) KR20200026826A (https=)
CN (1) CN110913889A (https=)
AU (1) AU2018280567A1 (https=)
CA (1) CA3066317A1 (https=)
IL (2) IL314423A (https=)
MX (1) MX2019014831A (https=)
TW (2) TW201904608A (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
SG192117A1 (en) 2011-01-28 2013-08-30 Sanofi Sa Human antibodies to pcsk9 for use in methods of treating particular groups of subjects
AR087305A1 (es) 2011-07-28 2014-03-12 Regeneron Pharma Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
CN118105480A (zh) 2013-11-12 2024-05-31 赛诺菲生物技术公司 用于与pcsk9抑制剂一起使用的给药方案
JP2018523684A (ja) 2015-08-18 2018-08-23 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. リポタンパク質アフェレーシスを受けている高脂血症の患者を治療するための抗pcsk9阻害抗体
CN113876956B (zh) * 2020-07-01 2023-07-04 陈敏 Pcsk9抑制剂在制备促进皮肤色素生成产品中的应用
CN114525258A (zh) * 2020-10-30 2022-05-24 未来智人再生医学研究院(广州)有限公司 一种表达pcsk9阻断物的多能干细胞或其衍生物及应用
CN115992138A (zh) * 2021-09-30 2023-04-21 北京安龙生物医药有限公司 用于治疗与pcsk9相关疾病的靶向寡核苷酸
CN116236582A (zh) * 2021-12-07 2023-06-09 广州嘉越医药科技有限公司 吲哚取代四氢异喹啉类化合物与他汀类化合物的联合应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3672B1 (ar) * 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
WO2015140079A1 (en) * 2014-03-17 2015-09-24 Sanofi Methods for treating subjects with primary hypercholesterolemia that is not adequately controlled
CA2955304C (en) * 2014-07-16 2023-12-12 Sanofi Biotechnology Methods for treating high cardiovascular risk patients with hypercholesterolemia
KR20230074283A (ko) * 2014-07-16 2023-05-26 사노피 바이오테크놀로지 이형접합성 가족성 고콜레스테롤혈증(heFH) 환자의 치료방법
JP2018523684A (ja) * 2015-08-18 2018-08-23 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. リポタンパク質アフェレーシスを受けている高脂血症の患者を治療するための抗pcsk9阻害抗体

Similar Documents

Publication Publication Date Title
JP2020522544A5 (https=)
Heuvelman et al. Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes
JP6379143B2 (ja) エクセナチドの経口投与用の方法及び組成物
RU2494755C2 (ru) Способы и композиции для перорального введения белков
Shah et al. Oral delivery of proteins: progress and prognostication
US20080213288A1 (en) Combined Use Of A Modulator Of CD3 And A GLP-1 Compound
US20140011733A1 (en) Combination of acylated glucagon analogues with insulin analogues
EP1515749B1 (en) Combined use of a modulator of cd3 and a glp-1 compound
KR20150047606A (ko) 고혈당증 치료를 위한 방법 및 조성물
CN105963685A (zh) 包含glp-1激动剂和n-(8-(2-羟基苯甲酰)氨基)辛酸盐的固体组合物
CN101505594A (zh) 代谢紊乱的组合治疗
Mittermayer et al. Addressing unmet medical needs in type 1 diabetes: a review of drugs under development
TW201904608A (zh) 藉由投予pcsk9抑制劑治療糖尿病患者高血脂症之方法
JP2014148524A (ja) 持続性血糖降下剤の投与方法
RU2670106C2 (ru) Фармацевтическая композиция
Bahtiyar et al. Cardiovascular effects of different GLP-1 receptor agonists in patients with type 2 diabetes
Viljoen et al. Glucagon-like peptide 1 therapy: from discovery to type 2 diabetes and beyond
Umpierrez et al. Reshaping diabetes care: the fundamental role of dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 receptor agonists in clinical practice
Rendell United States experience of insulin degludec alone or in combination for type 1 and type 2 diabetes
JP2021523214A5 (https=)
Groves et al. Standard and novel treatment options for metabolic syndrome and diabetes mellitus
Nauck et al. Incretin‐based therapies
WO2018204918A1 (en) Treatment of hepatic disorders
Jeon et al. Glucagon-like Peptide-1 Receptor Agonists
TWI919251B (zh) 使用gip/glp1共促效劑之療法