JP2020521459A - サテライト細胞および組成物ならびにそれらの生産方法 - Google Patents

サテライト細胞および組成物ならびにそれらの生産方法 Download PDF

Info

Publication number
JP2020521459A
JP2020521459A JP2019565174A JP2019565174A JP2020521459A JP 2020521459 A JP2020521459 A JP 2020521459A JP 2019565174 A JP2019565174 A JP 2019565174A JP 2019565174 A JP2019565174 A JP 2019565174A JP 2020521459 A JP2020521459 A JP 2020521459A
Authority
JP
Japan
Prior art keywords
naturally occurring
cells
cell
satellite cells
satellite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2019565174A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020521459A5 (https=
Inventor
リー エル． ルビン，
リー エル． ルビン，
フェオドル ディー． プライス，
フェオドル ディー． プライス，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Original Assignee
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of JP2020521459A publication Critical patent/JP2020521459A/ja
Publication of JP2020521459A5 publication Critical patent/JP2020521459A5/ja
Priority to JP2023093069A priority Critical patent/JP7840060B2/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • C12N5/0659—Satellite cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1323—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from skeletal muscle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2019565174A 2017-05-24 2018-05-24 サテライト細胞および組成物ならびにそれらの生産方法 Withdrawn JP2020521459A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023093069A JP7840060B2 (ja) 2017-05-24 2023-06-06 サテライト細胞および組成物ならびにそれらの生産方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762510617P 2017-05-24 2017-05-24
US62/510,617 2017-05-24
PCT/US2018/034458 WO2018218061A1 (en) 2017-05-24 2018-05-24 Satellite cells and compositions and methods for producing the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023093069A Division JP7840060B2 (ja) 2017-05-24 2023-06-06 サテライト細胞および組成物ならびにそれらの生産方法

Publications (2)

Publication Number Publication Date
JP2020521459A true JP2020521459A (ja) 2020-07-27
JP2020521459A5 JP2020521459A5 (https=) 2021-07-26

Family

ID=64397099

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019565174A Withdrawn JP2020521459A (ja) 2017-05-24 2018-05-24 サテライト細胞および組成物ならびにそれらの生産方法
JP2023093069A Active JP7840060B2 (ja) 2017-05-24 2023-06-06 サテライト細胞および組成物ならびにそれらの生産方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023093069A Active JP7840060B2 (ja) 2017-05-24 2023-06-06 サテライト細胞および組成物ならびにそれらの生産方法

Country Status (7)

Country Link
US (3) US11512291B2 (https=)
EP (1) EP3630129A4 (https=)
JP (2) JP2020521459A (https=)
CN (1) CN111051499A (https=)
AU (1) AU2018271982B2 (https=)
CA (1) CA3064763A1 (https=)
WO (1) WO2018218061A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111051499A (zh) 2017-05-24 2020-04-21 哈佛学院校长同事会 卫星细胞及其组合物和生产方法
CN115386539A (zh) * 2021-05-18 2022-11-25 南京大学 胸腺细胞在培养肌肉干细胞中的用途
CN116287202B (zh) * 2023-02-16 2026-03-03 中国人民解放军总医院第六医学中心 检测rbp1的试剂用于制备诊断房颤的试剂盒的用途
WO2025231290A1 (en) * 2024-05-01 2025-11-06 President And Fellows Of Harvard College Satellite cells and compositions and methods for producing the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524727A (ja) * 2009-04-27 2012-10-18 オタワ ホスピタル リサーチ インスティチュート 幹細胞を調節するための組成物および方法ならびにその使用
US20150111822A1 (en) * 2011-09-16 2015-04-23 Ottawa Hospital Research Institute Wnt7a compositions and method of using the same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270960A (en) 1964-09-11 1966-09-06 Sperry Rand Corp Fluid sensor
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CA2277278A1 (en) 1997-01-10 1998-07-16 Life Technologies, Inc. Embryonic stem cell serum replacement
CA2307807C (en) 1997-10-23 2008-09-02 Andrea G. Bodnar Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture
US7094874B2 (en) 2000-05-26 2006-08-22 Bristol-Myers Squibb Co. Soluble CTLA4 mutant molecules
US20030054331A1 (en) 2001-09-14 2003-03-20 Stemsource, Inc. Preservation of non embryonic cells from non hematopoietic tissues
US7592174B2 (en) 2002-05-31 2009-09-22 The Board Of Trustees Of The Leland Stanford Junior University Isolation of mesenchymal stem cells
JP2005532810A (ja) 2002-07-16 2005-11-04 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム 組織修復および組織形成のために間葉性幹細胞を移植する方法
WO2005071060A2 (en) * 2004-01-08 2005-08-04 North Carolina State University Methods and devices for microencapsulation of cells
NZ538097A (en) 2005-02-07 2006-07-28 Ovita Ltd Method and compositions for improving wound healing
CA2524619A1 (en) * 2005-11-22 2007-05-22 Ottawa Health Research Institute Novel stem cells, nucleotide sequences and proteins therefrom
US20070190056A1 (en) * 2006-02-07 2007-08-16 Ravi Kambadur Muscle regeneration compositions and uses therefor
JP2011514169A (ja) * 2008-03-17 2011-05-06 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 幹細胞培養のためのマイクロキャリア
EP2294185A2 (en) * 2008-05-08 2011-03-16 Coretherapix Slu Multipotent adult stem cell population
WO2010031190A1 (en) * 2008-09-22 2010-03-25 UNIVERSITé LAVAL Culture medium for myoblasts, precursors thereof and derivatives thereof
EP2864476A4 (en) * 2012-06-14 2016-04-06 Hutchinson Fred Cancer Res EX-VIVO EXPANSION OF MYOGENIC STEM CELLS THROUGH NOTCH ACTIVATION
CN111051499A (zh) 2017-05-24 2020-04-21 哈佛学院校长同事会 卫星细胞及其组合物和生产方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524727A (ja) * 2009-04-27 2012-10-18 オタワ ホスピタル リサーチ インスティチュート 幹細胞を調節するための組成物および方法ならびにその使用
US20150111822A1 (en) * 2011-09-16 2015-04-23 Ottawa Hospital Research Institute Wnt7a compositions and method of using the same

Also Published As

Publication number Publication date
EP3630129A4 (en) 2021-02-24
CN111051499A (zh) 2020-04-21
CA3064763A1 (en) 2018-11-19
US11512291B2 (en) 2022-11-29
EP3630129A1 (en) 2020-04-08
US20190203180A1 (en) 2019-07-04
AU2018271982A1 (en) 2019-12-19
JP2023105075A (ja) 2023-07-28
WO2018218061A1 (en) 2018-11-29
US11859211B2 (en) 2024-01-02
JP7840060B2 (ja) 2026-04-03
US20240228969A1 (en) 2024-07-11
AU2018271982B2 (en) 2025-05-29
US20230098750A1 (en) 2023-03-30

Similar Documents

Publication Publication Date Title
US11859211B2 (en) Satellite cells and compositions and methods for producing the same
US12492400B2 (en) Compositions and methods for induced tissue regeneration in mammalian species
US20240189363A1 (en) Cardiomyocytes and compositions and methods for producing the same
CN103200937A (zh) 用于肌肉修复和再生的组合物和方法
US20250188417A1 (en) Cardiomyocytes and compositions and methods for producing the same
EP3813852A1 (en) Methods to induce terminal differentiation in stem cells by interfering with dna replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof
US20250297224A1 (en) Cardiomyocytes and compositions and methods for producing the same
EP2898065B1 (en) Adipose tissue cells
WO2025231290A1 (en) Satellite cells and compositions and methods for producing the same
HK40078841A (zh) 心肌细胞和组合物及其产生方法
Samuelson Sca-1 positive pancreatic progenitor cells: a replacement for transplanted islets

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210517

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210517

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220428

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220727

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220927

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221028

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20230206

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230606

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20230613

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20230616