JP2020521459A5 - - Google Patents
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- JP2020521459A5 JP2020521459A5 JP2019565174A JP2019565174A JP2020521459A5 JP 2020521459 A5 JP2020521459 A5 JP 2020521459A5 JP 2019565174 A JP2019565174 A JP 2019565174A JP 2019565174 A JP2019565174 A JP 2019565174A JP 2020521459 A5 JP2020521459 A5 JP 2020521459A5
- Authority
- JP
- Japan
- Prior art keywords
- naturally occurring
- cell
- satellite cells
- composition
- occurring satellite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000001057 smooth muscle myoblast Anatomy 0.000 claims description 146
- 238000000034 method Methods 0.000 claims description 79
- 210000004027 cell Anatomy 0.000 claims description 68
- 108090000623 proteins and genes Proteins 0.000 claims description 60
- 239000000203 mixture Substances 0.000 claims description 44
- 210000003098 myoblast Anatomy 0.000 claims description 34
- 210000003205 muscle Anatomy 0.000 claims description 20
- 230000002062 proliferating effect Effects 0.000 claims description 14
- 230000005913 Notch signaling pathway Effects 0.000 claims description 12
- 208000014674 injury Diseases 0.000 claims description 12
- 210000002220 organoid Anatomy 0.000 claims description 12
- 210000002027 skeletal muscle Anatomy 0.000 claims description 12
- 230000008733 trauma Effects 0.000 claims description 12
- 230000032459 dedifferentiation Effects 0.000 claims description 10
- 101100351033 Mus musculus Pax7 gene Proteins 0.000 claims description 8
- 102100038380 Myogenic factor 5 Human genes 0.000 claims description 8
- 101710099061 Myogenic factor 5 Proteins 0.000 claims description 8
- 230000003412 degenerative effect Effects 0.000 claims description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 8
- 208000035475 disorder Diseases 0.000 claims description 8
- 238000000338 in vitro Methods 0.000 claims description 8
- 239000003094 microcapsule Substances 0.000 claims description 6
- 230000009756 muscle regeneration Effects 0.000 claims description 6
- 238000002054 transplantation Methods 0.000 claims description 6
- 101150117962 DUSP1 gene Proteins 0.000 claims description 4
- 208000029549 Muscle injury Diseases 0.000 claims description 4
- 101150016983 NFIA gene Proteins 0.000 claims description 4
- -1 Nm1 Proteins 0.000 claims description 4
- 102100030399 Protein sprouty homolog 1 Human genes 0.000 claims description 4
- 101710082100 Protein sprouty homolog 1 Proteins 0.000 claims description 4
- 101100174184 Serratia marcescens fosA gene Proteins 0.000 claims description 4
- 101001023030 Toxoplasma gondii Myosin-D Proteins 0.000 claims description 4
- 238000003556 assay Methods 0.000 claims description 4
- 230000004069 differentiation Effects 0.000 claims description 4
- 101150078861 fos gene Proteins 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 230000004044 response Effects 0.000 claims description 4
- 208000001076 sarcopenia Diseases 0.000 claims description 4
- 238000004114 suspension culture Methods 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 210000005260 human cell Anatomy 0.000 claims description 2
- 239000000126 substance Substances 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023093069A JP7840060B2 (ja) | 2017-05-24 | 2023-06-06 | サテライト細胞および組成物ならびにそれらの生産方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762510617P | 2017-05-24 | 2017-05-24 | |
| US62/510,617 | 2017-05-24 | ||
| PCT/US2018/034458 WO2018218061A1 (en) | 2017-05-24 | 2018-05-24 | Satellite cells and compositions and methods for producing the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093069A Division JP7840060B2 (ja) | 2017-05-24 | 2023-06-06 | サテライト細胞および組成物ならびにそれらの生産方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521459A JP2020521459A (ja) | 2020-07-27 |
| JP2020521459A5 true JP2020521459A5 (https=) | 2021-07-26 |
Family
ID=64397099
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565174A Withdrawn JP2020521459A (ja) | 2017-05-24 | 2018-05-24 | サテライト細胞および組成物ならびにそれらの生産方法 |
| JP2023093069A Active JP7840060B2 (ja) | 2017-05-24 | 2023-06-06 | サテライト細胞および組成物ならびにそれらの生産方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093069A Active JP7840060B2 (ja) | 2017-05-24 | 2023-06-06 | サテライト細胞および組成物ならびにそれらの生産方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11512291B2 (https=) |
| EP (1) | EP3630129A4 (https=) |
| JP (2) | JP2020521459A (https=) |
| CN (1) | CN111051499A (https=) |
| AU (1) | AU2018271982B2 (https=) |
| CA (1) | CA3064763A1 (https=) |
| WO (1) | WO2018218061A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111051499A (zh) | 2017-05-24 | 2020-04-21 | 哈佛学院校长同事会 | 卫星细胞及其组合物和生产方法 |
| CN115386539A (zh) * | 2021-05-18 | 2022-11-25 | 南京大学 | 胸腺细胞在培养肌肉干细胞中的用途 |
| CN116287202B (zh) * | 2023-02-16 | 2026-03-03 | 中国人民解放军总医院第六医学中心 | 检测rbp1的试剂用于制备诊断房颤的试剂盒的用途 |
| WO2025231290A1 (en) * | 2024-05-01 | 2025-11-06 | President And Fellows Of Harvard College | Satellite cells and compositions and methods for producing the same |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| CA2277278A1 (en) | 1997-01-10 | 1998-07-16 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| CA2307807C (en) | 1997-10-23 | 2008-09-02 | Andrea G. Bodnar | Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture |
| US7094874B2 (en) | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
| US20030054331A1 (en) | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| US7592174B2 (en) | 2002-05-31 | 2009-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Isolation of mesenchymal stem cells |
| JP2005532810A (ja) | 2002-07-16 | 2005-11-04 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム | 組織修復および組織形成のために間葉性幹細胞を移植する方法 |
| WO2005071060A2 (en) * | 2004-01-08 | 2005-08-04 | North Carolina State University | Methods and devices for microencapsulation of cells |
| NZ538097A (en) | 2005-02-07 | 2006-07-28 | Ovita Ltd | Method and compositions for improving wound healing |
| CA2524619A1 (en) * | 2005-11-22 | 2007-05-22 | Ottawa Health Research Institute | Novel stem cells, nucleotide sequences and proteins therefrom |
| US20070190056A1 (en) * | 2006-02-07 | 2007-08-16 | Ravi Kambadur | Muscle regeneration compositions and uses therefor |
| JP2011514169A (ja) * | 2008-03-17 | 2011-05-06 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 幹細胞培養のためのマイクロキャリア |
| EP2294185A2 (en) * | 2008-05-08 | 2011-03-16 | Coretherapix Slu | Multipotent adult stem cell population |
| WO2010031190A1 (en) * | 2008-09-22 | 2010-03-25 | UNIVERSITé LAVAL | Culture medium for myoblasts, precursors thereof and derivatives thereof |
| JP5802195B2 (ja) * | 2009-04-27 | 2015-10-28 | オタワ ホスピタル リサーチ インスティチュート | 幹細胞を調節するための組成物および方法ならびにその使用 |
| WO2013040341A2 (en) * | 2011-09-16 | 2013-03-21 | Ottawa Hospital Research Institute | Wnt7a compositions and methods of using the same |
| EP2864476A4 (en) * | 2012-06-14 | 2016-04-06 | Hutchinson Fred Cancer Res | EX-VIVO EXPANSION OF MYOGENIC STEM CELLS THROUGH NOTCH ACTIVATION |
| CN111051499A (zh) | 2017-05-24 | 2020-04-21 | 哈佛学院校长同事会 | 卫星细胞及其组合物和生产方法 |
-
2018
- 2018-05-24 CN CN201880047924.3A patent/CN111051499A/zh active Pending
- 2018-05-24 WO PCT/US2018/034458 patent/WO2018218061A1/en not_active Ceased
- 2018-05-24 CA CA3064763A patent/CA3064763A1/en active Pending
- 2018-05-24 EP EP18805776.4A patent/EP3630129A4/en active Pending
- 2018-05-24 AU AU2018271982A patent/AU2018271982B2/en active Active
- 2018-05-24 JP JP2019565174A patent/JP2020521459A/ja not_active Withdrawn
-
2019
- 2019-03-08 US US16/297,548 patent/US11512291B2/en active Active
-
2022
- 2022-11-23 US US17/993,690 patent/US11859211B2/en active Active
-
2023
- 2023-06-06 JP JP2023093069A patent/JP7840060B2/ja active Active
- 2023-11-13 US US18/508,093 patent/US20240228969A1/en active Pending
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