JP2020520992A - がん性腫瘍の治療方法 - Google Patents

がん性腫瘍の治療方法 Download PDF

Info

Publication number
JP2020520992A
JP2020520992A JP2020514151A JP2020514151A JP2020520992A JP 2020520992 A JP2020520992 A JP 2020520992A JP 2020514151 A JP2020514151 A JP 2020514151A JP 2020514151 A JP2020514151 A JP 2020514151A JP 2020520992 A JP2020520992 A JP 2020520992A
Authority
JP
Japan
Prior art keywords
dose
radiation
catheter device
chemotherapeutic agent
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020514151A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020520992A5 (https=
Inventor
アガー,ラムティン
ナジマバーディ,カムラン
アール. バガイ,ショーン
アール. バガイ,ショーン
Original Assignee
レノボアールエックス,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by レノボアールエックス,インコーポレイテッド filed Critical レノボアールエックス,インコーポレイテッド
Publication of JP2020520992A publication Critical patent/JP2020520992A/ja
Publication of JP2020520992A5 publication Critical patent/JP2020520992A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12136Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/1204Type of occlusion temporary occlusion
    • A61B17/12045Type of occlusion temporary occlusion double occlusion, e.g. during anastomosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • A61M2025/1015Multiple balloon catheters having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1052Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/005Devices for introducing or retaining media, e.g. remedies, in cavities of the body for contrast media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020514151A 2017-05-18 2018-05-18 がん性腫瘍の治療方法 Pending JP2020520992A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762507962P 2017-05-18 2017-05-18
US62/507,962 2017-05-18
US15/807,011 US10695543B2 (en) 2017-05-18 2017-11-08 Methods for treating cancerous tumors
US15/807,011 2017-11-08
PCT/US2018/033482 WO2018213760A1 (en) 2017-05-18 2018-05-18 Methods for treating cancerous tumors

Publications (2)

Publication Number Publication Date
JP2020520992A true JP2020520992A (ja) 2020-07-16
JP2020520992A5 JP2020520992A5 (https=) 2021-07-29

Family

ID=64270271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020514151A Pending JP2020520992A (ja) 2017-05-18 2018-05-18 がん性腫瘍の治療方法

Country Status (5)

Country Link
US (1) US10695543B2 (https=)
EP (1) EP3624794A1 (https=)
JP (1) JP2020520992A (https=)
CN (1) CN109982698A (https=)
WO (1) WO2018213760A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025512317A (ja) * 2022-11-11 2025-04-17 レノボアールエックス,インコーポレイテッド 栄養血管を通して薬剤を送達するための方法および装置

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10512761B2 (en) 2009-12-02 2019-12-24 Renovorx, Inc. Methods for delivery of therapeutic materials to treat pancreatic cancer
US9539081B2 (en) 2009-12-02 2017-01-10 Surefire Medical, Inc. Method of operating a microvalve protection device
US11020444B2 (en) * 2010-04-23 2021-06-01 Scicotec Gmbh Transluminal delivery of viruses for treatment of diseased tissue
EP3043863B1 (en) 2013-09-11 2019-12-04 The Board of Trustees of the Leland Stanford Junior University Arrays of accelerating structures and rapid imaging for facilitating rapid radiation therapies
US9968740B2 (en) 2014-03-25 2018-05-15 Surefire Medical, Inc. Closed tip dynamic microvalve protection device
US20160287839A1 (en) 2015-03-31 2016-10-06 Surefire Medical, Inc. Apparatus and Method for Infusing an Immunotherapy Agent to a Solid Tumor for Treatment
US10780250B1 (en) 2016-09-19 2020-09-22 Surefire Medical, Inc. System and method for selective pressure-controlled therapeutic delivery
US11400263B1 (en) 2016-09-19 2022-08-02 Trisalus Life Sciences, Inc. System and method for selective pressure-controlled therapeutic delivery
US10588636B2 (en) 2017-03-20 2020-03-17 Surefire Medical, Inc. Dynamic reconfigurable microvalve protection device
US12290564B2 (en) 2017-05-18 2025-05-06 Renovorx, Inc. Methods and apparatuses for treating tumors
US11052224B2 (en) 2017-05-18 2021-07-06 Renovorx, Inc. Methods for treating cancerous tumors
EP3654976A1 (en) * 2017-07-21 2020-05-27 Varian Medical Systems, Inc. Methods of use of ultra-high dose rate radiation and therapeutic agents
US11850398B2 (en) 2018-08-01 2023-12-26 Trisalus Life Sciences, Inc. Systems and methods for pressure-facilitated therapeutic agent delivery
US11338117B2 (en) 2018-10-08 2022-05-24 Trisalus Life Sciences, Inc. Implantable dual pathway therapeutic agent delivery port
US12433597B2 (en) 2019-06-04 2025-10-07 Trisalus Life Sciences, Inc. Atraumatic occlusive system with compartment for measurement of vascular pressure change
CN117794618A (zh) * 2021-06-14 2024-03-29 诺沃库勒有限责任公司 用交变电场、放射性粒子和全身疗法治疗和预防癌症的方法
US20240285338A1 (en) * 2021-06-16 2024-08-29 Pulse Biosciences, Inc. Apparatus and method for delivering pulsed electric field therapy
AU2023371657A1 (en) 2022-11-04 2025-05-15 Solvein Inc. Catheters and related methods for aspiration and controlled delivery of closure agents
US11911581B1 (en) 2022-11-04 2024-02-27 Controlled Delivery Systems, Inc. Catheters and related methods for the aspiration controlled delivery of closure agents
WO2024238755A1 (en) * 2023-05-16 2024-11-21 DiNAQOR USA Isolation and treatment of an organ or tumor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140276135A1 (en) * 2009-12-02 2014-09-18 Renovorx, Inc. Devices, methods and kits for delivery of therapeutic materials to a pancreas
WO2016070032A1 (en) * 2014-10-30 2016-05-06 Neurotronic, Inc. Chemical ablation and method of treatment for various diseases
JP2017500144A (ja) * 2013-12-27 2017-01-05 レナルプロ・メディカル・インコーポレーテッドRenalpro Medical,Inc. 急性腎障害の治療用デバイスと治療方法

Family Cites Families (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4445892A (en) 1982-05-06 1984-05-01 Laserscope, Inc. Dual balloon catheter device
US4883459A (en) 1983-07-29 1989-11-28 Reynaldo Calderon Retrograde perfusion
US4714460A (en) 1983-07-29 1987-12-22 Reynaldo Calderon Methods and systems for retrograde perfusion in the body for curing it of the disease or immume deficiency
US4696304A (en) 1984-09-10 1987-09-29 Thomas J. Fogarty Thermodilution flow-directed catheter assembly and method
US4655746A (en) 1985-12-02 1987-04-07 Target Therapeutics Catheter device
JPH01207078A (ja) 1988-02-15 1989-08-21 Terumo Corp カテーテルチュブおよび内視鏡
US4830003A (en) 1988-06-17 1989-05-16 Wolff Rodney G Compressive stent and delivery system
US5575815A (en) 1988-08-24 1996-11-19 Endoluminal Therapeutics, Inc. Local polymeric gel therapy
US5069662A (en) 1988-10-21 1991-12-03 Delcath Systems, Inc. Cancer treatment
JP3137646B2 (ja) 1991-04-05 2001-02-26 ボストン サイエンティフィック コーポレイション 硬度調節可能な可変カテーテル器具
US5281200A (en) 1992-12-08 1994-01-25 Cordis Corporation Multiple component balloon catheter system and stenosis treatment procedure
US5318535A (en) 1993-06-21 1994-06-07 Baxter International Inc. Low-profile dual-lumen perfusion balloon catheter with axially movable inner guide sheath
US6113576A (en) 1993-08-04 2000-09-05 Lake Region Manufacturing, Inc. Thrombolysis catheter system with fixed length infusion zone
US5338301A (en) 1993-08-26 1994-08-16 Cordis Corporation Extendable balloon-on-a-wire catheter, system and treatment procedure
US5462529A (en) 1993-09-29 1995-10-31 Technology Development Center Adjustable treatment chamber catheter
US5397307A (en) 1993-12-07 1995-03-14 Schneider (Usa) Inc. Drug delivery PTCA catheter and method for drug delivery
US5419763B1 (en) 1994-01-04 1997-07-15 Cor Trak Medical Inc Prostatic drug-delivery catheter
US5415636A (en) 1994-04-13 1995-05-16 Schneider (Usa) Inc Dilation-drug delivery catheter
US5484412A (en) 1994-04-19 1996-01-16 Pierpont; Brien E. Angioplasty method and means for performing angioplasty
US5478309A (en) 1994-05-27 1995-12-26 William P. Sweezer, Jr. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US5836905A (en) 1994-06-20 1998-11-17 Lemelson; Jerome H. Apparatus and methods for gene therapy
US5514092A (en) 1994-08-08 1996-05-07 Schneider (Usa) Inc. Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration
US5833672A (en) 1994-12-12 1998-11-10 Nippon Zeon Co., Ltd. Double tube, balloon catheter produced by using double tube, and process for producing balloon catheter
WO1996030073A1 (en) 1995-03-30 1996-10-03 Heartport, Inc. Endovascular cardiac venting catheter and method
US5833650A (en) 1995-06-05 1998-11-10 Percusurge, Inc. Catheter apparatus and method for treating occluded vessels
WO1997003715A1 (en) * 1995-07-21 1997-02-06 The General Hospital Corporation Method and apparatus of enhancing the delivery of a pharmaceutical formulation
US5925016A (en) 1995-09-27 1999-07-20 Xrt Corp. Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure
US6440097B1 (en) 1995-10-06 2002-08-27 Target Therapeutics, Inc. Balloon catheter with delivery side holes
JPH09117510A (ja) 1995-10-26 1997-05-06 Buaayu:Kk インフュージョンカテーテル
US5843050A (en) 1995-11-13 1998-12-01 Micro Therapeutics, Inc. Microcatheter
FR2748212B1 (fr) 1996-05-06 1998-07-31 Nycomed Lab Sa Catheter destine a la delivrance locale d'une substance therapeutiquement active
AU3122197A (en) 1996-05-14 1997-12-05 Embol-X, Inc. Aortic occluder with associated filter and methods of use during cardiac surgery
US6022336A (en) 1996-05-20 2000-02-08 Percusurge, Inc. Catheter system for emboli containment
US5833644A (en) 1996-05-20 1998-11-10 Percusurge, Inc. Method for emboli containment
US6270477B1 (en) 1996-05-20 2001-08-07 Percusurge, Inc. Catheter for emboli containment
US6325826B1 (en) 1998-01-14 2001-12-04 Advanced Stent Technologies, Inc. Extendible stent apparatus
KR20000070731A (ko) 1997-02-04 2000-11-25 찰스 더블유 프란즈 치골 상부 배출 카테터
US5919135A (en) * 1997-02-28 1999-07-06 Lemelson; Jerome System and method for treating cellular disorders in a living being
US6176844B1 (en) 1997-05-22 2001-01-23 Peter Y. Lee Catheter system for the isolation of a segment of blood vessel
ATE267625T1 (de) 1997-06-23 2004-06-15 Schneider Europ Gmbh Katheteranordnung
US5919163A (en) 1997-07-14 1999-07-06 Delcath Systems, Inc. Catheter with slidable balloon
US5968012A (en) 1997-08-22 1999-10-19 Scimed Lifesystems, Inc. Balloon catheter with adjustable shaft
US20010041862A1 (en) 1997-09-02 2001-11-15 Morton G. Glickman Novel apparatus and method of treating a tumor in the extremity of a patient
US5961536A (en) 1997-10-14 1999-10-05 Scimed Life Systems, Inc. Catheter having a variable length balloon and method of using the same
US6375634B1 (en) * 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US6699231B1 (en) 1997-12-31 2004-03-02 Heartport, Inc. Methods and apparatus for perfusion of isolated tissue structure
US6986788B2 (en) 1998-01-30 2006-01-17 Synthes (U.S.A.) Intervertebral allograft spacer
WO2002074178A2 (en) 2001-02-15 2002-09-26 Endovia Medical, Inc. Flexible surgical instrument
US6156053A (en) 1998-05-01 2000-12-05 Intella Interventional Systems, Inc. Dual catheter assembly
US6508777B1 (en) 1998-05-08 2003-01-21 Cardeon Corporation Circulatory support system and method of use for isolated segmental perfusion
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
US6206283B1 (en) 1998-12-23 2001-03-27 At&T Corp. Method and apparatus for transferring money via a telephone call
KR20010052377A (ko) 1998-05-21 2001-06-25 윌리암 디. 누난 치료용 물질을 압력 조절에 의해 선택적으로 전달시키는방법 및 캐뉼라
JPH11342208A (ja) 1998-06-02 1999-12-14 Buaayu:Kk バルーンカテーテル
US6083198A (en) 1998-06-25 2000-07-04 Cardiovention, Inc. Perfusion catheter providing segmented flow regions and methods of use
US6461327B1 (en) 1998-08-07 2002-10-08 Embol-X, Inc. Atrial isolator and method of use
US6165152A (en) 1998-09-11 2000-12-26 Advanced Cardiovascular Systems, Inc. Catheter with a flexible tip and taper and method of manufacture
US6051014A (en) 1998-10-13 2000-04-18 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery and methods of use
US7780628B1 (en) 1999-01-11 2010-08-24 Angiodynamics, Inc. Apparatus and methods for treating congestive heart disease
US6743196B2 (en) 1999-03-01 2004-06-01 Coaxia, Inc. Partial aortic occlusion devices and methods for cerebral perfusion augmentation
US6287290B1 (en) 1999-07-02 2001-09-11 Pulmonx Methods, systems, and kits for lung volume reduction
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6575932B1 (en) 1999-12-02 2003-06-10 Ottawa Heart Institute Adjustable multi-balloon local delivery device
US6929633B2 (en) 2000-01-25 2005-08-16 Bacchus Vascular, Inc. Apparatus and methods for clot dissolution
US6482172B1 (en) 2000-02-09 2002-11-19 Jeffrey J. Thramann Flow-by channel catheter and method of use
US6346098B1 (en) 2000-03-07 2002-02-12 The Board Of Trustees Of The Leland Stanford Junior University Methods and kits for locally administering an active agent to an interstitial space of a host
US6485500B1 (en) 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
US6685672B1 (en) 2000-07-13 2004-02-03 Edwards Lifesciences Corporation Multi-balloon drug delivery catheter for angiogenesis
US6569146B1 (en) 2000-08-18 2003-05-27 Scimed Life Systems, Inc. Method and apparatus for treating saphenous vein graft lesions
US6692458B2 (en) 2000-12-19 2004-02-17 Edwards Lifesciences Corporation Intra-pericardial drug delivery device with multiple balloons and method for angiogenesis
US6436090B1 (en) 2000-12-21 2002-08-20 Advanced Cardiovascular Systems, Inc. Multi lumen catheter shaft
US7179251B2 (en) 2001-01-17 2007-02-20 Boston Scientific Scimed, Inc. Therapeutic delivery balloon
US7357794B2 (en) 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6602241B2 (en) 2001-01-17 2003-08-05 Transvascular, Inc. Methods and apparatus for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6749581B2 (en) 2001-02-02 2004-06-15 Medtronic, Inc. Variable infusion rate catheter
US7766894B2 (en) 2001-02-15 2010-08-03 Hansen Medical, Inc. Coaxial catheter system
US6887227B1 (en) 2001-02-23 2005-05-03 Coaxia, Inc. Devices and methods for preventing distal embolization from the vertebrobasilar artery using flow reversal
US6520183B2 (en) 2001-06-11 2003-02-18 Memorial Sloan-Kettering Cancer Center Double endobronchial catheter for one lung isolation anesthesia and surgery
US6682499B2 (en) 2001-06-28 2004-01-27 Jay Alan Lenker Method and apparatus for venous drainage and retrograde coronary perfusion
US6706013B1 (en) 2001-06-29 2004-03-16 Advanced Cardiovascular Systems, Inc. Variable length drug delivery catheter
US6533800B1 (en) 2001-07-25 2003-03-18 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow
US7452532B2 (en) 2001-09-30 2008-11-18 Scicotec Gmbh Transluminal application of adult stem cells for body organ tissue repair
CA2476263C (en) 2002-02-01 2012-08-21 Robert J. Goldman Multi-function catheter and use thereof
US8062251B2 (en) 2002-02-01 2011-11-22 Vascular Designs, Inc. Multi-function catheter and use thereof
US7503904B2 (en) 2002-04-25 2009-03-17 Cardiac Pacemakers, Inc. Dual balloon telescoping guiding catheter
US7250041B2 (en) 2003-03-12 2007-07-31 Abbott Cardiovascular Systems Inc. Retrograde pressure regulated infusion
US20050015048A1 (en) 2003-03-12 2005-01-20 Chiu Jessica G. Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof
JP2004337400A (ja) 2003-05-16 2004-12-02 Terumo Corp 薬剤投与キット
US20050059931A1 (en) 2003-09-16 2005-03-17 Venomatrix Methods and apparatus for localized and semi-localized drug delivery
US20050059930A1 (en) 2003-09-16 2005-03-17 Michi Garrison Method and apparatus for localized drug delivery
JP3877075B2 (ja) 2004-01-28 2007-02-07 有限会社エスアールジェイ 内視鏡装置
EP1715826B1 (en) 2004-02-02 2013-03-06 Conceptus, Inc. Enhancing tissue ingrowth for contraception
US7815624B2 (en) 2004-05-18 2010-10-19 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
JP2008519659A (ja) 2004-11-12 2008-06-12 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 静脈閉塞装置および使用法
US7947030B2 (en) 2004-12-30 2011-05-24 Reynaldo Calderon Retrograde perfusion of tumor sites
US7789846B2 (en) 2005-01-25 2010-09-07 Thermopeutix, Inc. System and methods for selective thermal treatment
US8721592B2 (en) 2006-01-25 2014-05-13 Thermopeutix, Inc. Variable length catheter for drug delivery
US7708715B2 (en) 2005-03-21 2010-05-04 Boston Scientific Scimed, Inc. Tissue approximation device
US7515957B2 (en) 2005-06-23 2009-04-07 Medtronic Vascular, Inc. Catheter-based, dual balloon photopolymerization system
AU2006284540A1 (en) 2005-08-25 2007-03-01 Osprey Medical Inc. Devices and methods for perfusing an organ
DE102005042338B4 (de) 2005-09-06 2007-07-05 Siemens Ag Kathetereinrichtung
US8172792B2 (en) 2005-12-27 2012-05-08 Tyco Healthcare Group Lp Embolic protection systems for bifurcated conduits
WO2007081842A2 (en) 2006-01-09 2007-07-19 University Of Virginia Patent Foundation Multi-port catheter system with medium control and measurement systems for therapy and diagnosis delivery
US8177829B2 (en) 2006-08-23 2012-05-15 Boston Scientific Scimed, Inc. Auxiliary balloon catheter
US20100106181A1 (en) 2007-01-08 2010-04-29 Yossi Gross In-situ filter
JP2009034462A (ja) 2007-07-31 2009-02-19 Koosei Advance:Kk 膵臓治療用灌流システム
US8182446B2 (en) 2007-09-12 2012-05-22 Cook Medical Technologies Balloon catheter for delivering a therapeutic agent
CA2705073C (en) 2007-11-07 2016-12-06 Rodney James Lane Systems, methods and devices for circulatory access
US8043257B2 (en) 2007-12-06 2011-10-25 Abbott Cardiovascular Systems Inc. Agent delivery catheter having an inflation bridge between two axially spaced balloons
US20090198093A1 (en) * 2008-02-06 2009-08-06 Oliver Meissner System and method for combined embolization and ablation therapy
EP2110151A1 (en) 2008-04-16 2009-10-21 Edward Diethrich Double balloon occlusion device
US20090275918A1 (en) 2008-05-01 2009-11-05 Stemcor Systems, Inc. Pancreatic delivery catheter
AU2009293312B2 (en) 2008-09-18 2015-07-09 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8162879B2 (en) 2008-09-22 2012-04-24 Tyco Healthcare Group Lp Double balloon catheter and methods for homogeneous drug delivery using the same
CN102271747B (zh) 2008-11-03 2014-06-04 先端导管治疗公司 闭塞灌流导管
US8540667B2 (en) 2008-11-12 2013-09-24 Sanovas, Inc. Multi-balloon catheter for extravasated drug delivery
US8444624B2 (en) 2009-10-19 2013-05-21 Vatrix Medical, Inc. Vascular medical devices with sealing elements and procedures for the treatment of isolated vessel sections
EP2506913B8 (en) 2009-12-02 2020-11-18 RenovoRX, Inc. Devices and kits for delivery of therapeutic materials to a pancreas
US10512761B2 (en) 2009-12-02 2019-12-24 Renovorx, Inc. Methods for delivery of therapeutic materials to treat pancreatic cancer
US20160082178A1 (en) 2009-12-02 2016-03-24 Renovorx, Inc. Angiographic methods for identification of feeder vessels
EP2555824A4 (en) 2010-04-08 2013-09-11 Bio2Medical Inc CATHETER CONNECTOR
EP2672925B1 (en) 2011-02-08 2017-05-03 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations
US8597239B2 (en) 2011-03-01 2013-12-03 Sanovas, Inc. Abrading balloon catheter for extravasated drug delivery
US9180281B2 (en) 2011-04-08 2015-11-10 Sanovas, Inc. Adjustable balloon catheter for extravasated drug delivery
US8702678B2 (en) 2011-08-03 2014-04-22 Venous Therapy, Inc. Assemblies, systems, and methods for infusing therapeutic agents into the body
US20140214002A1 (en) 2013-01-27 2014-07-31 Thermopeutix, Inc. Bifurcation catheter with variable length occlusion elements
JP6401781B2 (ja) * 2013-05-08 2018-10-10 エンボルクス, インク.Embolx, Inc. 一体型流量調整による経血管的腫瘍塞栓形成の装置及び方法
WO2014197362A1 (en) 2013-06-03 2014-12-11 Ramtin Agah Devices, methods and kits for delivery of therapeutic materials to a pancreas
BR112017000800A8 (pt) 2014-07-17 2023-04-25 Biocurity Holdings Inc Tratamento do câncer com uma combinação de radiação, nanoparticulas de óxido de cério, e um agente quimioterápico
US9889120B2 (en) 2016-01-14 2018-02-13 Vicus Therapeutics, Llc Combination drug therapies for cancer and methods of making and using them

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140276135A1 (en) * 2009-12-02 2014-09-18 Renovorx, Inc. Devices, methods and kits for delivery of therapeutic materials to a pancreas
JP2017500144A (ja) * 2013-12-27 2017-01-05 レナルプロ・メディカル・インコーポレーテッドRenalpro Medical,Inc. 急性腎障害の治療用デバイスと治療方法
WO2016070032A1 (en) * 2014-10-30 2016-05-06 Neurotronic, Inc. Chemical ablation and method of treatment for various diseases
JP2017533036A (ja) * 2014-10-30 2017-11-09 ニューロトロニック・インコーポレイテッドNeurotronic, Inc. 様々な疾患のための処置の化学的アブレーションおよび方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025512317A (ja) * 2022-11-11 2025-04-17 レノボアールエックス,インコーポレイテッド 栄養血管を通して薬剤を送達するための方法および装置
JP7842485B2 (ja) 2022-11-11 2026-04-08 レノボアールエックス,インコーポレイテッド 栄養血管を通して薬剤を送達するための方法および装置

Also Published As

Publication number Publication date
CN109982698A (zh) 2019-07-05
US20180333563A1 (en) 2018-11-22
WO2018213760A1 (en) 2018-11-22
US10695543B2 (en) 2020-06-30
EP3624794A1 (en) 2020-03-25

Similar Documents

Publication Publication Date Title
JP2020520992A (ja) がん性腫瘍の治療方法
US11052224B2 (en) Methods for treating cancerous tumors
US12290564B2 (en) Methods and apparatuses for treating tumors
Lewis et al. Locoregional drug delivery using image-guided intra-arterial drug eluting bead therapy
CA2874661C (en) Control catheters and methods for pulmonary suffusion and related therapies
US20100298622A1 (en) Apparatuses and techniques for bioactive drug delivery in the prostate gland
Crane et al. The argument for pre-operative chemoradiation for localized, radiographically resectable pancreatic cancer
de Baere et al. Arterial therapies of colorectal cancer metastases to the liver
Crane et al. Future chemoradiation strategies in pancreatic cancer
Vogl et al. Palliative hepatic intraarterial chemotherapy (HIC) using a novel combination of gemcitabine and mitomycin C: results in hepatic metastases
JP7842485B2 (ja) 栄養血管を通して薬剤を送達するための方法および装置
RU2722349C2 (ru) Способ лечения нерезектабельных и потенциально резектабельных метастазов колорекального рака в печени
Maruo et al. Percutaneous pelvic perfusion with extracorporeal chemofiltration for advanced uterine cervical carcinoma
Wu et al. Endovascular implantation of iodine-125 seed strand combined and stent placement for locally advanced pancreatic ductal adenocarcinoma with vascular invasion: a prospective single-arm pilot study
RU2276613C1 (ru) Способ лечения злокачественных опухолей головки поджелудочной железы
Lane et al. Safety and feasibility of repeatable hepatic vascular isolation chemotherapy: a pilot study
Avritscher et al. Transcatheter intra-arterial limb infusion for extremity osteosarcoma: technical considerations and outcomes
Nielsen et al. Irreversible electroporation of liver tumors
Lau et al. Loco-regional intervention for hepatocellular carcinoma
RU2547999C1 (ru) Способ лечения аденогенного местно-распространенного рака нижнеампулярного отдела прямой кишки
WO2025240796A1 (en) Methods and apparatuses for delivering an agent through vasa vasorum of a vessel
Seidel et al. Part I: Regional chemotherapy clinical studies in nontraditional clinical settings
Shen et al. TIPS-21 PHASE I/II STUDY OF STEREOTACTIC RADIOSURGERY WITH CONCURRENT OLAPARIB FOLLOWED BY ADJUVANT DURVALUMAB AND PHYSICIAN’S CHOICE SYSTEMIC THERAPY IN SUBJECTS WITH BREAST CANCER BRAIN METASTASES (SOLARA)
Patel et al. Image-Guided BrachyAblation (IGBA) for Liver Metastases and Primary Liver Cancers
Hänninen et al. Interventional radiotherapy

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210430

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210430

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220502

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220802

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221003

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230105

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230405

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230911

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20231208

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240403