JP2020519866A5 - - Google Patents

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Publication number
JP2020519866A5
JP2020519866A5 JP2019560168A JP2019560168A JP2020519866A5 JP 2020519866 A5 JP2020519866 A5 JP 2020519866A5 JP 2019560168 A JP2019560168 A JP 2019560168A JP 2019560168 A JP2019560168 A JP 2019560168A JP 2020519866 A5 JP2020519866 A5 JP 2020519866A5
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JP
Japan
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light
frequency
activity
item
physical property
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JP2019560168A
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Japanese (ja)
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JP2020519866A (ja
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Priority claimed from PCT/US2018/029234 external-priority patent/WO2018204135A2/en
Publication of JP2020519866A publication Critical patent/JP2020519866A/ja
Publication of JP2020519866A5 publication Critical patent/JP2020519866A5/ja
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JP2019560168A 2017-05-03 2018-04-24 ２光子蛍光測定を用いてタンパク質構造を決定する方法 Pending JP2020519866A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762500912P 2017-05-03 2017-05-03
US62/500,912 2017-05-03
PCT/US2018/029234 WO2018204135A2 (en) 2017-05-03 2018-04-24 Methods of determining protein structure using two-photon fluorescence measurements

Publications (2)

Publication Number Publication Date
JP2020519866A JP2020519866A (ja) 2020-07-02
JP2020519866A5 true JP2020519866A5 (enExample) 2021-06-10

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ID=64016774

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JP2019560168A Pending JP2020519866A (ja) 2017-05-03 2018-04-24 ２光子蛍光測定を用いてタンパク質構造を決定する方法

Country Status (5)

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US (1) US20200132604A1 (enExample)
EP (1) EP3619537A4 (enExample)
JP (1) JP2020519866A (enExample)
CN (1) CN110832322A (enExample)
WO (1) WO2018204135A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3455628A4 (en) 2016-05-09 2019-12-04 Biodesy, Inc. METHOD AND DEVICES FOR DETECTING INTERACTIONS OF PERIPHERAL MEMBRANE PROTEINS USING NONLINEAR OPTICAL TECHNIQUES
CN115236047A (zh) * 2017-05-23 2022-10-25 浜松光子学株式会社 取向特性测定方法、取向特性测定程序及取向特性测定装置
US11500352B2 (en) * 2019-05-01 2022-11-15 Dh Technologies Development Pte. Ltd. System and method for monitoring a production process
CN112102900B (zh) * 2020-10-12 2024-02-23 北京晶泰科技有限公司 一种基于TopoMA定量构效关系模型的药物设计方法
CN113456089B (zh) * 2021-06-30 2023-12-05 中国科学院半导体研究所 一种兼顾电生理信号记录的微型荧光成像系统
WO2023095154A1 (en) * 2021-11-24 2023-06-01 Sensoville Biotech Pvt Ltd Method for determining changes in a protein's structure
CN114113314B (zh) * 2021-11-25 2024-03-22 厦门大学 一种用于滨海核电站的海洋致灾生物水声监测系统及方法
CN115356276B (zh) * 2022-07-26 2025-07-22 武汉新烽光电股份有限公司 含有固体残留物的检测试剂的吸光度值估计方法及系统
CN118737306B (zh) * 2024-06-28 2025-09-19 西安电子科技大学 基于强化隐扩散模型的共价药物从头设计方法及相关装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3761898B2 (ja) * 1996-12-03 2006-03-29 ソイニ，エルッキ 生体特異性二光子励起蛍光検出方法およびそのための装置
US6953694B2 (en) * 2000-12-06 2005-10-11 The Trustees Of Columbia University In The City Of New York Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces
US7253287B1 (en) * 2004-05-14 2007-08-07 Research Foundation Of The University Of Central Florida, Inc. Reactive probes for two-photon fluorescent imaging and sensing
US9395358B2 (en) * 2012-02-05 2016-07-19 Biodesy, Inc. Methods for detecting allosteric modulators of protein
EP2841951B1 (en) * 2012-04-25 2019-12-11 Biodesy, Inc. Methods for detecting allosteric modulators of proteins
EP3237906B8 (en) * 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
CN107615047A (zh) * 2015-04-02 2018-01-19 比奥德赛公司 利用表面选择性非线性光学技术确定蛋白质结构的方法

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