JP2020517640A5 - - Google Patents

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Publication number
JP2020517640A5
JP2020517640A5 JP2019556889A JP2019556889A JP2020517640A5 JP 2020517640 A5 JP2020517640 A5 JP 2020517640A5 JP 2019556889 A JP2019556889 A JP 2019556889A JP 2019556889 A JP2019556889 A JP 2019556889A JP 2020517640 A5 JP2020517640 A5 JP 2020517640A5
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JP
Japan
Prior art keywords
adc
agent
cancer
individual
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019556889A
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English (en)
Japanese (ja)
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JP2020517640A (ja
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Publication date
Priority claimed from GBGB1706259.7A external-priority patent/GB201706259D0/en
Priority claimed from GBGB1706257.1A external-priority patent/GB201706257D0/en
Priority claimed from GBGB1706260.5A external-priority patent/GB201706260D0/en
Priority claimed from GBGB1706253.0A external-priority patent/GB201706253D0/en
Priority claimed from GBGB1706256.3A external-priority patent/GB201706256D0/en
Priority claimed from GBGB1706258.9A external-priority patent/GB201706258D0/en
Priority claimed from GBGB1706254.8A external-priority patent/GB201706254D0/en
Priority claimed from GBGB1706261.3A external-priority patent/GB201706261D0/en
Priority claimed from GBGB1802947.0A external-priority patent/GB201802947D0/en
Priority claimed from GBGB1805660.6A external-priority patent/GB201805660D0/en
Application filed filed Critical
Priority claimed from PCT/EP2018/060215 external-priority patent/WO2018193105A1/en
Publication of JP2020517640A publication Critical patent/JP2020517640A/ja
Publication of JP2020517640A5 publication Critical patent/JP2020517640A5/ja
Pending legal-status Critical Current

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JP2019556889A 2017-04-20 2018-04-20 併用療法 Pending JP2020517640A (ja)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
GB1706260.5 2017-04-20
GB1706256.3 2017-04-20
GB1706259.7 2017-04-20
GBGB1706253.0A GB201706253D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706254.8 2017-04-20
GBGB1706256.3A GB201706256D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706258.9A GB201706258D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706257.1 2017-04-20
GBGB1706259.7A GB201706259D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706258.9 2017-04-20
GBGB1706260.5A GB201706260D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706261.3 2017-04-20
GBGB1706261.3A GB201706261D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706254.8A GB201706254D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706253.0 2017-04-20
GBGB1706257.1A GB201706257D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1802947.0A GB201802947D0 (en) 2018-02-23 2018-02-23 Combination therapy
GB1802947.0 2018-02-23
GBGB1805660.6A GB201805660D0 (en) 2018-04-05 2018-04-05 Combination Therapy
GB1805660.6 2018-04-05
PCT/EP2018/060215 WO2018193105A1 (en) 2017-04-20 2018-04-20 Combination therapy

Publications (2)

Publication Number Publication Date
JP2020517640A JP2020517640A (ja) 2020-06-18
JP2020517640A5 true JP2020517640A5 (enExample) 2021-08-12

Family

ID=62111031

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019556889A Pending JP2020517640A (ja) 2017-04-20 2018-04-20 併用療法

Country Status (10)

Country Link
US (2) US20200405879A1 (enExample)
EP (1) EP3612839A1 (enExample)
JP (1) JP2020517640A (enExample)
KR (1) KR20190137151A (enExample)
CN (1) CN110869765A (enExample)
AU (1) AU2018253951A1 (enExample)
BR (1) BR112019021822A2 (enExample)
CA (1) CA3057749A1 (enExample)
MX (1) MX2019012462A (enExample)
WO (1) WO2018193105A1 (enExample)

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SMT201700160T1 (it) 2013-04-25 2017-05-08 Beigene Ltd Composti eterociclici fusi come inibitori di protein chinasi
ES2792183T3 (es) 2013-09-13 2020-11-10 Beigene Switzerland Gmbh Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico
CN106604742B (zh) 2014-07-03 2019-01-11 百济神州有限公司 抗pd-l1抗体及其作为治疗剂及诊断剂的用途
CN109475536B (zh) 2016-07-05 2022-05-27 百济神州有限公司 用于治疗癌症的PD-l拮抗剂和RAF抑制剂的组合
WO2018033853A2 (en) 2016-08-16 2018-02-22 Beigene, Ltd. Crystalline form of (s)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
PT3500299T (pt) 2016-08-19 2024-02-21 Beigene Switzerland Gmbh Combinação de zanubrutinib com um anticorpo anti-cd20 ou anti-pd-1 para utilização no tratamento do cancro
CN110461847B (zh) 2017-01-25 2022-06-07 百济神州有限公司 (S)-7-(1-(丁-2-炔酰基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氢吡唑并[1,5-a]嘧啶-3-甲酰胺的结晶形式、其制备及用途
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
TW202515616A (zh) 2017-06-26 2025-04-16 英屬開曼群島商百濟神州有限公司 抗pd-1抗體或其抗原結合片段在製備治療用於患有肝細胞癌(hcc)之藥物的用途
CN110997677A (zh) 2017-08-12 2020-04-10 百济神州有限公司 具有改进的双重选择性的Btk抑制剂
WO2019108795A1 (en) 2017-11-29 2019-06-06 Beigene Switzerland Gmbh Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
CA3107085A1 (en) * 2018-08-31 2020-03-05 Adc Therapeutics Sa Combination of anti-cd19 antibody-pyrroloenzodiazepine conjugate and ve netoclax
WO2020109251A1 (en) * 2018-11-29 2020-06-04 Adc Therapeutics Sa Dosage regime
BR112021014112A2 (pt) * 2019-01-18 2021-10-13 Dracen Pharmaceuticals, Inc. Usos de composto pró-fármaco de don e inibidor de ponto de controle imunológico para tratar câncer, bem como composto e composição farmacêutica compreendendo o mesmo
CN110128551A (zh) * 2019-06-05 2019-08-16 上海科弈药业科技有限公司 一种针对cd19+肿瘤的多功能融合蛋白及其应用
GB201908128D0 (en) * 2019-06-07 2019-07-24 Adc Therapeutics Sa Pyrrolobenzodiazepine-antibody conjugates
WO2020249001A1 (zh) 2019-06-10 2020-12-17 百济神州瑞士有限责任公司 一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法
JP7740994B2 (ja) * 2019-06-10 2025-09-17 アーデーセー セラピューティクス ソシエテ アノニム 抗cd19抗体薬物複合体とpi3k阻害剤又は二次薬剤を含む併用治療
EP4167920A4 (en) 2020-06-18 2024-06-12 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
GB202011993D0 (en) 2020-07-31 2020-09-16 Adc Therapeutics Sa ANTI-IL 13Ra2 antibodies
TW202244059A (zh) * 2021-04-30 2022-11-16 瑞士商赫孚孟拉羅股份公司 用抗cd20/抗cd3雙特異性抗體進行治療之給藥
US20250352658A1 (en) 2021-06-29 2025-11-20 Adc Therapeutics Sa Combination therapy using antibody-drug conjugates
JP2024534608A (ja) 2021-09-23 2024-09-20 サード ポール,インコーポレイテッド 一酸化窒素を送達するシステム及び方法
US11786531B1 (en) 2022-06-08 2023-10-17 Beigene Switzerland Gmbh Methods of treating B-cell proliferative disorder
EP4410314A1 (en) * 2023-02-02 2024-08-07 ADC Therapeutics SA Combination therapy comprising anti-cd22 antibody-drug conjugate and irak1 inhibitor

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EP2524929A1 (en) * 2011-05-17 2012-11-21 Sanofi Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
EP2550975A1 (en) * 2011-07-29 2013-01-30 Sanofi Combination therapy for the treatment of CD19+ B-cell malignancies symptoms comprising an anti-CD19 maytansinoid immunoconjugate and rituximab
HUE045435T2 (hu) * 2012-10-12 2019-12-30 Medimmune Ltd Pirrolobenzodiazepinek és konjugátumaik
HRP20182129T1 (hr) * 2012-10-12 2019-02-08 Adc Therapeutics Sa Konjugati protutijelo - pirolobenzodiazepin
RU2700092C2 (ru) * 2013-05-02 2019-09-12 Ф.Хоффманн-Ля Рош Аг Комбинированная терапия на основе афукозилированного антитела к cd20 в сочетании с конъюгатом антитело к cd22 - лекарственное средство
US9950078B2 (en) * 2013-10-11 2018-04-24 Medimmune Limited Pyrrolobenzodiazepine-antibody conjugates
GB201506399D0 (en) * 2015-04-15 2015-05-27 Berkel Patricius H C Van And Howard Philip W Site-specific antibody-drug conjugates

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