JP2020516692A5 - - Google Patents

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JP2020516692A5
JP2020516692A5 JP2020506139A JP2020506139A JP2020516692A5 JP 2020516692 A5 JP2020516692 A5 JP 2020516692A5 JP 2020506139 A JP2020506139 A JP 2020506139A JP 2020506139 A JP2020506139 A JP 2020506139A JP 2020516692 A5 JP2020516692 A5 JP 2020516692A5
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JP
Japan
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wavelengths
tissues
dye
light
fluorescent
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Pending
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JP2020506139A
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JP2020516692A (ja
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Priority claimed from PCT/US2018/061282 external-priority patent/WO2019099672A1/en
Publication of JP2020516692A publication Critical patent/JP2020516692A/ja
Publication of JP2020516692A5 publication Critical patent/JP2020516692A5/ja
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蛍光化合物は、蛍光色素であり得る。本開示の蛍光色素は、その吸収波長、励起波長、及び発光波長の全てが、約350nmまたはそれ以上の近赤外(NIR)または可視光のスペクトル範囲内に収まる傾向がある。このことは、診断処置に有益である。可視光及びNIR光は組織を損傷する恐れが低いためである。約350nmまたはそれ以上の波長を有する光は、組織に浸透する傾向があり、これにより、約350nm未満のUV波長を使用した場合には到達できない可能性がある関心組織において診断処置を実施することが可能になる。適切な蛍光染料としては、アクリジン、アクリドン、アントラセン、アントラサイクリン、アントラキノン、アザアズレン、アゾアズレン、ベンゼン、ベンゾイミダゾール、ベンゾフラン、ベンゾインドカルボシアニン、ベンゾインドール、ベンゾチオフェン、カルバゾール、クマリン、シアニン、ジベンゾフラン、ジベンゾチオフェン、ジピロロ染料、フラボン、フルオレセイン、イミダゾール、インドカルボシアニン、インドシアニン、インドール、イソインドール、イソキノリン、ナフタセンジオン、ナフタレン、ナフトキノン、フェナントレン、フェナントリジン、フェナントリジン、フェノセレナジン、フェノチアジン、フェノキサジン、フェニルキサンテン、ポリフルオロベンゼン、プリン、ピラジン、ピラゾール、ピリジン、ピリミドン、ピロール、量子ドット、キノリン、キノロン、ローダミン、スクアライン、テトラセン、チオフェン、トリフェニルメタン染料、キサンテン、キサントン、及びそれらの誘導体が挙げられる。
JP2020506139A 2017-11-20 2018-11-15 血漿中の蛍光化合物を調製及び分析する方法 Pending JP2020516692A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762588606P 2017-11-20 2017-11-20
US62/588,606 2017-11-20
PCT/US2018/061282 WO2019099672A1 (en) 2017-11-20 2018-11-15 Method for preparing and analyzing fluorescent compounds in plasma

Publications (2)

Publication Number Publication Date
JP2020516692A JP2020516692A (ja) 2020-06-11
JP2020516692A5 true JP2020516692A5 (ja) 2021-03-11

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ID=66532776

Family Applications (1)

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JP2020506139A Pending JP2020516692A (ja) 2017-11-20 2018-11-15 血漿中の蛍光化合物を調製及び分析する方法

Country Status (16)

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US (1) US11674965B2 (ja)
EP (1) EP3713577A4 (ja)
JP (1) JP2020516692A (ja)
KR (2) KR20200007778A (ja)
CN (1) CN110461332A (ja)
AU (1) AU2018369913B2 (ja)
BR (1) BR112019021044A2 (ja)
CA (1) CA3058762A1 (ja)
IL (1) IL269611A (ja)
MX (1) MX2019011901A (ja)
MY (1) MY188418A (ja)
PH (1) PH12019502373A1 (ja)
RU (1) RU2746503C1 (ja)
SG (1) SG11201909366XA (ja)
WO (1) WO2019099672A1 (ja)
ZA (1) ZA201906445B (ja)

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CN113109491A (zh) * 2020-01-13 2021-07-13 四川基因格司法鉴定中心 从生物样本中检测毒药物的通用方法
TW202233586A (zh) * 2020-11-10 2022-09-01 美商麥迪貝肯有限公司 吡𠯤化合物的皮下與肌內注射
EP4313172A1 (en) * 2021-03-31 2024-02-07 Medibeacon Inc. Preparation of substituted diaminopyrazine dicarboxylic acids
US20220315538A1 (en) * 2021-03-31 2022-10-06 Medibeacon Inc. Purification of substituted diaminopyrazine dicarboxylic acids
TW202321203A (zh) * 2021-08-11 2023-06-01 中國大陸商杭州中美華東製藥有限公司 製備作為螢光示蹤劑的吡嗪羧酸類衍生物的方法
CN117881665A (zh) * 2021-08-27 2024-04-12 杭州中美华东制药有限公司 吡嗪类衍生物的晶型及其制备方法

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JP4647742B2 (ja) * 2000-03-13 2011-03-09 三菱化学メディエンス株式会社 アスコルビン酸の分析方法及び分析用試薬
US6969592B2 (en) * 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy
US6909912B2 (en) 2002-06-20 2005-06-21 University Of Florida Non-invasive perfusion monitor and system, specially configured oximeter probes, methods of using same, and covers for probes
AU2004233870B2 (en) 2003-04-24 2009-11-05 The Board Of Regents Of The University Of Texas System Noninvasive blood analysis by optical probing of the veins under the tongue
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JP4214109B2 (ja) * 2004-12-16 2009-01-28 日本ハム株式会社 畜水産物中の残留動物用薬剤の抽出液
DE602005020981D1 (de) 2004-12-23 2010-06-10 Mallinckrodt Inc Fluoreszente pyrazinderivate und verfahren zu deren anwendung bei der bewertung der nierenfunktion
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EP2139485B1 (en) * 2007-04-11 2012-10-17 BioMarin Pharmaceutical Inc. Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring
CN102770751A (zh) 2010-02-23 2012-11-07 B.R.A.H.M.S有限公司 测定小体积体液样品中的标志物的方法
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AU2012249600B2 (en) 2011-04-26 2016-05-19 Incube Labs, Llc Mouthpiece for measurement of biometric data of a diver and underwater communication
WO2016183351A1 (en) 2015-05-12 2016-11-17 Medibeacon Inc. Compositions and methods for assessing eye vasculature

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