JP2020516655A5 - - Google Patents
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- Publication number
- JP2020516655A5 JP2020516655A5 JP2019555941A JP2019555941A JP2020516655A5 JP 2020516655 A5 JP2020516655 A5 JP 2020516655A5 JP 2019555941 A JP2019555941 A JP 2019555941A JP 2019555941 A JP2019555941 A JP 2019555941A JP 2020516655 A5 JP2020516655 A5 JP 2020516655A5
- Authority
- JP
- Japan
- Prior art keywords
- amhrii
- binding agent
- agent according
- seq
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305446.1 | 2017-04-14 | ||
| EP17305446 | 2017-04-14 | ||
| PCT/EP2018/059553 WO2018189381A1 (en) | 2017-04-14 | 2018-04-13 | Amhrii-binding compounds for preventing or treating lung cancers |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020516655A JP2020516655A (ja) | 2020-06-11 |
| JP2020516655A5 true JP2020516655A5 (https=) | 2021-05-20 |
| JP7289420B2 JP7289420B2 (ja) | 2023-06-12 |
| JP7289420B6 JP7289420B6 (ja) | 2023-06-30 |
Family
ID=58672546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555941A Active JP7289420B6 (ja) | 2017-04-14 | 2018-04-13 | 肺癌を予防又は処置する為のａｍｈｒｉｉ結合性化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230227566A1 (https=) |
| EP (1) | EP3609919A1 (https=) |
| JP (1) | JP7289420B6 (https=) |
| KR (2) | KR102759138B1 (https=) |
| CN (1) | CN110944665B (https=) |
| BR (1) | BR112019021495A8 (https=) |
| CA (1) | CA3058541A1 (https=) |
| MX (2) | MX2019012136A (https=) |
| WO (1) | WO2018189381A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020516668A (ja) * | 2017-04-14 | 2020-06-11 | ガママブス ファルマ | 癌を予防又は処置する為のａｍｈｒｉｉ結合性化合物 |
| EP3917967A4 (en) * | 2019-02-01 | 2023-02-08 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | Microenvironment sensors to regulate engineered gene expression |
| WO2020243679A1 (en) * | 2019-05-31 | 2020-12-03 | Detti Laura | Anti-mullerian hormone receptor binding peptides |
| EP4034151A1 (en) * | 2019-09-27 | 2022-08-03 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of müllerian inhibiting substance inhibitors for treating cancer |
| US20230078601A1 (en) * | 2020-01-31 | 2023-03-16 | The Cleveland Clinic Foundation | Anti-mullerian hormone receptor 2 antibodies and methods of use |
| KR20240149925A (ko) * | 2022-02-16 | 2024-10-15 | 더 클리브랜드 클리닉 파운데이션 | Amhr2-ed 암 백신 제제 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| CA2194907A1 (en) | 1994-07-13 | 1996-02-01 | Kouji Matsushima | Reshaped human antibody against human interleukin-8 |
| US6242195B1 (en) | 1998-04-02 | 2001-06-05 | Genentech, Inc. | Methods for determining binding of an analyte to a receptor |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
| ES2292236T3 (es) | 1998-04-02 | 2008-03-01 | Genentech, Inc. | Variantes de anticuerpos y sus fragmentos. |
| HU230769B1 (hu) | 1999-01-15 | 2018-03-28 | Genentech Inc. | Módosított effektor-funkciójú polipeptid-változatok |
| WO2005005615A2 (en) * | 2003-07-08 | 2005-01-20 | Fox Chase Cancer Center | Anti-mullerian inhibiting substance type ii receptor (misiir) immunoconjugates to detect and treat cancer |
| EP1918304A1 (en) | 2006-11-02 | 2008-05-07 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Monoclonal antibodies against the human anti-müllerian hormone type II receptor (AMHR-II) |
| US20100233689A1 (en) * | 2007-03-22 | 2010-09-16 | The General Hospital Corporation | Pyrazoloanthrone and derivatives thereof for the treatment of cancer expressing 'mullerian inhibiting substance' type ii receptor (misrii) and of excess androgen states |
| FR2959994B1 (fr) | 2010-05-12 | 2012-08-24 | Lfb Biotechnologies | Nouveaux anticorps humanises 12g4 mutes et leurs fragments diriges contre le recepteur humain de l'hormone anti-mullerienne de type ii |
| CA2837472A1 (en) * | 2011-05-27 | 2012-12-06 | Fox Chase Cancer Center | Rationally-designed anti-mullerian inhibiting substance type ii receptor antibodies |
| FR2984750B1 (fr) * | 2011-12-23 | 2014-01-10 | Lfb Biotechnologies | Nouvelles compositions pharmaceutiques comprenant un anticorps liant le recepteur humain de l'hormone anti-mullerienne de type ii |
| EP3331569A1 (en) | 2015-08-07 | 2018-06-13 | Gamamabs Pharma | Antibodies, antibody drug conjugates and methods of use |
| US11261225B2 (en) * | 2017-02-10 | 2022-03-01 | Institute For Cancer Research | Chimera of bone morphogenic protein 2 and the Müllerian-inhibiting substance type II receptor binding region of Müllerian-inhibiting substance |
| JP2020516668A (ja) * | 2017-04-14 | 2020-06-11 | ガママブス ファルマ | 癌を予防又は処置する為のａｍｈｒｉｉ結合性化合物 |
-
2018
- 2018-04-13 KR KR1020197033360A patent/KR102759138B1/ko active Active
- 2018-04-13 BR BR112019021495A patent/BR112019021495A8/pt unknown
- 2018-04-13 JP JP2019555941A patent/JP7289420B6/ja active Active
- 2018-04-13 CA CA3058541A patent/CA3058541A1/en active Pending
- 2018-04-13 MX MX2019012136A patent/MX2019012136A/es unknown
- 2018-04-13 CN CN201880040211.4A patent/CN110944665B/zh not_active Expired - Fee Related
- 2018-04-13 EP EP18718420.5A patent/EP3609919A1/en not_active Withdrawn
- 2018-04-13 US US16/605,053 patent/US20230227566A1/en not_active Abandoned
- 2018-04-13 WO PCT/EP2018/059553 patent/WO2018189381A1/en not_active Ceased
- 2018-04-13 KR KR1020257001888A patent/KR20250017758A/ko active Pending
-
2019
- 2019-10-09 MX MX2024003228A patent/MX2024003228A/es unknown
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