JP2020511481A5 - - Google Patents

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Publication number
JP2020511481A5
JP2020511481A5 JP2019551449A JP2019551449A JP2020511481A5 JP 2020511481 A5 JP2020511481 A5 JP 2020511481A5 JP 2019551449 A JP2019551449 A JP 2019551449A JP 2019551449 A JP2019551449 A JP 2019551449A JP 2020511481 A5 JP2020511481 A5 JP 2020511481A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
variable domain
heavy chain
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Application number
JP2019551449A
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English (en)
Japanese (ja)
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JP7170331B2 (ja
JP2020511481A (ja
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Priority claimed from US15/871,802 external-priority patent/US20180142019A1/en
Application filed filed Critical
Priority claimed from PCT/US2018/023860 external-priority patent/WO2018175790A1/en
Publication of JP2020511481A publication Critical patent/JP2020511481A/ja
Publication of JP2020511481A5 publication Critical patent/JP2020511481A5/ja
Application granted granted Critical
Publication of JP7170331B2 publication Critical patent/JP7170331B2/ja
Active legal-status Critical Current
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JP2019551449A 2017-03-22 2018-03-22 固形及び血液癌の治療のための併用療法 Active JP7170331B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762475032P 2017-03-22 2017-03-22
US201762475036P 2017-03-22 2017-03-22
US62/475,032 2017-03-22
US62/475,036 2017-03-22
US15/871,802 2018-01-15
US15/871,802 US20180142019A1 (en) 2016-10-21 2018-01-15 Therapeutic cd47 antibodies
PCT/US2018/023860 WO2018175790A1 (en) 2017-03-22 2018-03-22 Combination therapy for the treatment of solid and hematological cancers

Publications (3)

Publication Number Publication Date
JP2020511481A JP2020511481A (ja) 2020-04-16
JP2020511481A5 true JP2020511481A5 (https=) 2021-05-06
JP7170331B2 JP7170331B2 (ja) 2022-11-14

Family

ID=63585757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019551449A Active JP7170331B2 (ja) 2017-03-22 2018-03-22 固形及び血液癌の治療のための併用療法

Country Status (7)

Country Link
EP (1) EP3600393A4 (https=)
JP (1) JP7170331B2 (https=)
CN (1) CN111148535A (https=)
AU (1) AU2018240377A1 (https=)
CA (1) CA3057139A1 (https=)
SG (1) SG11201908602UA (https=)
WO (1) WO2018175790A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9221908B2 (en) 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
BR112015013431A2 (pt) 2012-12-12 2017-11-14 Vasculox Inc anticorpos monoclonais ou respectivos fragmentos ligantes de antígenos, composição farmacêutica, e usos de anticorpo monoclonal ou respectivo fragmento ligante de antígenos
RU2748401C2 (ru) 2015-09-18 2021-05-25 Арч Онколоджи, Инк. Терапевтические антитела к CD47
EP3529276A4 (en) 2016-10-21 2020-06-17 Arch Oncology, Inc. CD47 THERAPEUTIC ANTIBODIES
US20220017615A1 (en) * 2018-12-03 2022-01-20 Shanghai Pharmaexplorer Co., Ltd. Cd47 antibody, preparation method therefor and uses thereof
WO2020232427A2 (en) * 2019-05-16 2020-11-19 Arch Oncology, Inc. Therapeutic compositions and methods for treating cancer in combination with analogs of interleukin proteins
US20200400662A1 (en) 2019-06-07 2020-12-24 ALX Oncology Inc. Methods and reagents for reducing the interference of drugs that bind cd47 in serological assays
JP2022553410A (ja) * 2019-10-23 2022-12-22 アーチ オンコロジー，インコーポレイテッド 固形がんおよび血液がんを処置するための併用療法
CA3164623A1 (en) 2019-12-17 2021-06-24 Pfizer Inc. Antibodies specific for cd47, pd-l1, and uses thereof
EP4190813A4 (en) * 2020-07-31 2025-02-12 Bio-Thera Solutions, Ltd. CD47 ANTIBODIES AND THEIR APPLICATION
US20220196651A1 (en) 2020-12-06 2022-06-23 ALX Oncology Inc. Multimers for reducing the interference of drugs that bind cd47 in serological assays

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696325B2 (en) * 1999-03-10 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Polypeptide inducing apoptosis
CA2545166A1 (en) * 2003-11-11 2005-05-19 Chugai Seiyaku Kabushiki Kaisha Humanized anti-cd47 antibody
CN101970499B (zh) * 2008-02-11 2014-12-31 治疗科技公司 用于肿瘤治疗的单克隆抗体
RU2012131663A (ru) * 2010-01-21 2014-02-27 Иммьюноджен, Инк. Композиции и способы лечения рака яичников
KR102100388B1 (ko) * 2012-02-06 2020-04-13 인히브릭스, 인크. Cd47 항체 및 그 사용 방법
IN2014KN00920A (https=) * 2012-06-21 2015-10-09 Compugen Ltd
US9221908B2 (en) * 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
NZ710695A (en) * 2013-02-06 2020-05-29 Inhibrx Inc Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof
RU2748401C2 (ru) * 2015-09-18 2021-05-25 Арч Онколоджи, Инк. Терапевтические антитела к CD47

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