JP2020511481A5 - - Google Patents
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- JP2020511481A5 JP2020511481A5 JP2019551449A JP2019551449A JP2020511481A5 JP 2020511481 A5 JP2020511481 A5 JP 2020511481A5 JP 2019551449 A JP2019551449 A JP 2019551449A JP 2019551449 A JP2019551449 A JP 2019551449A JP 2020511481 A5 JP2020511481 A5 JP 2020511481A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- variable domain
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762475032P | 2017-03-22 | 2017-03-22 | |
| US201762475036P | 2017-03-22 | 2017-03-22 | |
| US62/475,032 | 2017-03-22 | ||
| US62/475,036 | 2017-03-22 | ||
| US15/871,802 | 2018-01-15 | ||
| US15/871,802 US20180142019A1 (en) | 2016-10-21 | 2018-01-15 | Therapeutic cd47 antibodies |
| PCT/US2018/023860 WO2018175790A1 (en) | 2017-03-22 | 2018-03-22 | Combination therapy for the treatment of solid and hematological cancers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020511481A JP2020511481A (ja) | 2020-04-16 |
| JP2020511481A5 true JP2020511481A5 (https=) | 2021-05-06 |
| JP7170331B2 JP7170331B2 (ja) | 2022-11-14 |
Family
ID=63585757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019551449A Active JP7170331B2 (ja) | 2017-03-22 | 2018-03-22 | 固形及び血液癌の治療のための併用療法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP3600393A4 (https=) |
| JP (1) | JP7170331B2 (https=) |
| CN (1) | CN111148535A (https=) |
| AU (1) | AU2018240377A1 (https=) |
| CA (1) | CA3057139A1 (https=) |
| SG (1) | SG11201908602UA (https=) |
| WO (1) | WO2018175790A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9221908B2 (en) | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| MX2015007446A (es) | 2012-12-12 | 2015-12-07 | Vasculox Inc | Anticuerpos terapeuticos para cd47. |
| BR112018005322A2 (pt) | 2015-09-18 | 2018-12-11 | Arch Oncology, Inc. | anticorpo monoclonal ou seu fragmento de ligação a antígenos, composição farmacêutica, anticorpo monoclonal ou seu fragmento de ligação a antígenos para uso, método de tratamento de lesão de isquemia-reperfusão, método de tratamento de câncer em um paciente humano, método de avaliação da expressão de cd47 em células tumorais e/ou imunes usando um anticorpo monoclonal ou seu fragmento de ligação a antígenos |
| EP3529276A4 (en) | 2016-10-21 | 2020-06-17 | Arch Oncology, Inc. | CD47 THERAPEUTIC ANTIBODIES |
| EP3892637A1 (en) * | 2018-12-03 | 2021-10-13 | Shanghai Pharmaexplorer Co., Ltd. | Cd47 antibody, preparation method therefor and uses thereof |
| WO2020232427A2 (en) * | 2019-05-16 | 2020-11-19 | Arch Oncology, Inc. | Therapeutic compositions and methods for treating cancer in combination with analogs of interleukin proteins |
| CN114206912B (zh) | 2019-06-07 | 2025-02-11 | Alx肿瘤生物技术公司 | 用于在血清学测定中减少结合cd47的药物的干扰的方法和试剂 |
| JP2022553410A (ja) * | 2019-10-23 | 2022-12-22 | アーチ オンコロジー，インコーポレイテッド | 固形がんおよび血液がんを処置するための併用療法 |
| JP7369297B2 (ja) | 2019-12-17 | 2023-10-25 | ファイザー・インク | Ｃｄ４７、ｐｄ－ｌ１に特異的な抗体、およびその使用 |
| JP7789304B2 (ja) * | 2020-07-31 | 2025-12-22 | バイオ－テラ ソリュ－ションズ，エルティーディー． | Ｃｄ４７抗体及びその応用 |
| WO2022120286A1 (en) | 2020-12-06 | 2022-06-09 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7696325B2 (en) * | 1999-03-10 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide inducing apoptosis |
| JP4637749B2 (ja) * | 2003-11-11 | 2011-02-23 | 中外製薬株式会社 | ヒト化抗ｃｄ４７抗体 |
| PT2242773T (pt) * | 2008-02-11 | 2017-09-15 | Cure Tech Ltd | Anticorpos monoclonais para o tratamento de tumores |
| EP2526118A4 (en) * | 2010-01-21 | 2013-11-13 | Immunogen Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF EGG CANCER |
| KR102338833B1 (ko) * | 2012-02-06 | 2021-12-13 | 인히브릭스, 인크. | Cd47 항체 및 그 사용 방법 |
| EP2744830A4 (en) * | 2012-06-21 | 2015-06-17 | Compugen Ltd | LSR ANTIBODIES AND USES THEREOF FOR THE TREATMENT OF CANCER |
| US9221908B2 (en) * | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| CN105101997B (zh) * | 2013-02-06 | 2018-11-09 | 印希彼有限合伙公司 | 不减少血小板和不减少血红细胞的cd47抗体及其使用方法 |
| BR112018005322A2 (pt) * | 2015-09-18 | 2018-12-11 | Arch Oncology, Inc. | anticorpo monoclonal ou seu fragmento de ligação a antígenos, composição farmacêutica, anticorpo monoclonal ou seu fragmento de ligação a antígenos para uso, método de tratamento de lesão de isquemia-reperfusão, método de tratamento de câncer em um paciente humano, método de avaliação da expressão de cd47 em células tumorais e/ou imunes usando um anticorpo monoclonal ou seu fragmento de ligação a antígenos |
-
2018
- 2018-03-22 SG SG11201908602U patent/SG11201908602UA/en unknown
- 2018-03-22 AU AU2018240377A patent/AU2018240377A1/en not_active Abandoned
- 2018-03-22 CA CA3057139A patent/CA3057139A1/en active Pending
- 2018-03-22 WO PCT/US2018/023860 patent/WO2018175790A1/en not_active Ceased
- 2018-03-22 CN CN201880028490.2A patent/CN111148535A/zh active Pending
- 2018-03-22 EP EP18771103.1A patent/EP3600393A4/en not_active Withdrawn
- 2018-03-22 JP JP2019551449A patent/JP7170331B2/ja active Active
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