JP2020507624A5 - - Google Patents

Download PDF

Info

Publication number
JP2020507624A5
JP2020507624A5 JP2019563696A JP2019563696A JP2020507624A5 JP 2020507624 A5 JP2020507624 A5 JP 2020507624A5 JP 2019563696 A JP2019563696 A JP 2019563696A JP 2019563696 A JP2019563696 A JP 2019563696A JP 2020507624 A5 JP2020507624 A5 JP 2020507624A5
Authority
JP
Japan
Prior art keywords
cancer
optionally substituted
independently
groups
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019563696A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020507624A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2018/050342 external-priority patent/WO2018146468A1/en
Publication of JP2020507624A publication Critical patent/JP2020507624A/ja
Publication of JP2020507624A5 publication Critical patent/JP2020507624A5/ja
Pending legal-status Critical Current

Links

JP2019563696A 2017-02-07 2018-02-07 スルフィニルピリジンおよび癌の治療におけるそれらの使用 Pending JP2020507624A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762455645P 2017-02-07 2017-02-07
US62/455,645 2017-02-07
PCT/GB2018/050342 WO2018146468A1 (en) 2017-02-07 2018-02-07 Sulfinylpyridines and their use in the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2020507624A JP2020507624A (ja) 2020-03-12
JP2020507624A5 true JP2020507624A5 (https=) 2021-03-11

Family

ID=61226605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019563696A Pending JP2020507624A (ja) 2017-02-07 2018-02-07 スルフィニルピリジンおよび癌の治療におけるそれらの使用

Country Status (12)

Country Link
US (2) US11208384B2 (https=)
EP (1) EP3580204A1 (https=)
JP (1) JP2020507624A (https=)
KR (1) KR20190115011A (https=)
CN (1) CN110382465A (https=)
AU (1) AU2018218518B2 (https=)
BR (1) BR112019016258A2 (https=)
CA (1) CA3051644A1 (https=)
MA (1) MA47450A (https=)
MX (1) MX2019009356A (https=)
RU (1) RU2019127896A (https=)
WO (1) WO2018146468A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
AU2018218519B2 (en) 2017-02-07 2021-08-05 Oblique Therapeutics Ab Heteroarylsulfonyl-substituted pyridines and their use in the treatment of cancer
MA47450A (fr) * 2017-02-07 2019-12-18 Oblique Therapeutics Ab Sulfinylpyridines et leur utilisation dans le traitement du cancer
CA3051539A1 (en) 2017-02-07 2018-08-16 Oblique Therapeutics Ab Hydrocarbylsulfonyl-substituted pyridines and their use in the treatment of cancer
US11168069B2 (en) 2017-02-07 2021-11-09 Oblique Therapeutics Ab Heterocyclylsulfonyl-substituted pyridines and their use in the treatment of cancer
EP3752151A1 (en) * 2018-02-12 2020-12-23 Cinda Pharma AB Thioredoxin reductase inhibitors for use in the treatment of cancer

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3064846D1 (en) 1979-12-19 1983-10-20 Duphar Int Res New nitrothiophenes, method of preparing the new compounds, as well as fungicidal and/or bactericidal compositions on the basis of the new compounds
AU543161B2 (en) 1980-03-07 1985-04-04 E.I. Du Pont De Nemours And Company Pyrimidine or s.triazine derivatives
US4456469A (en) 1980-03-07 1984-06-26 E. I. Du Pont De Nemours And Company Pyridyl sulfone herbicides
US4791127A (en) 1985-10-07 1988-12-13 Nippon Kayaku Kabushiki Kaisha Alkanesulfonate derivatives and their use as insecticides, acaricides or nematicides
DE3812177A1 (de) * 1988-04-13 1989-10-26 Bayer Ag 2-phenylsulfinyl-nitro-pyridine, verfahren zu ihrer herstellung und ihre verwendung
WO1995029897A1 (en) 1994-04-29 1995-11-09 G.D. Searle & Co. METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS
US6069144A (en) 1995-08-24 2000-05-30 Basf Aktiengesellschaft N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications
DE19531148A1 (de) 1995-08-24 1997-02-27 Basf Ag Fungizide Pyridin-2-yl-Derivate
US6191280B1 (en) 1997-05-30 2001-02-20 Basf Aktiengesellschaft Method for producing substituted thiopyridines
US6284923B1 (en) 1997-08-22 2001-09-04 Tularik Inc Substituted benzene compounds as antiproliferative and cholesterol lowering action
WO1999018096A1 (en) 1997-10-02 1999-04-15 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US6297239B1 (en) 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US6191170B1 (en) 1998-01-13 2001-02-20 Tularik Inc. Benzenesulfonamides and benzamides as therapeutic agents
SI0930302T1 (en) 1998-01-16 2003-10-31 F. Hoffmann-La Roche Ag Benzosulfone derivatives
AU2001250783A1 (en) 2000-02-29 2001-09-12 Cor Therapeutics, Inc. Benzamides and related inhibitors of factor xa
US20030187026A1 (en) 2001-12-13 2003-10-02 Qun Li Kinase inhibitors
WO2003068744A1 (en) 2002-02-18 2003-08-21 Ishihara Sangyo Kaisha, Ltd. Pyridine derivatives or salts thereof and cytokine production inhibitors containing the same
US20030236287A1 (en) 2002-05-03 2003-12-25 Piotrowski David W. Positive allosteric modulators of the nicotinic acetylcholine receptor
US7037902B2 (en) 2002-07-03 2006-05-02 Receptron, Inc. Affinity small molecules for the EPO receptor
US7915293B2 (en) 2003-05-30 2011-03-29 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
EA011671B1 (ru) 2004-06-04 2009-04-28 Арена Фармасьютикалз, Инк. Замещенные производные арила и гетероарила в качестве модуляторов метаболизма и для профилактики и лечения связанных с ним расстройств
US20060019967A1 (en) 2004-07-21 2006-01-26 Su-Ying Wu SARS CoV main protease inhibitors
GB0426313D0 (en) 2004-12-01 2005-01-05 Merck Sharp & Dohme Therapeutic agents
WO2006083692A2 (en) 2005-01-28 2006-08-10 Mount Sinai Schoool Of Medicine Methods of identifying modulators of bromodomains
GB0504828D0 (en) 2005-03-09 2005-04-13 Merck Sharp & Dohme Therapeutic agents
WO2007076875A2 (en) 2006-01-06 2007-07-12 Aarhus Universitet Compounds acting on the serotonin transporter
CA2647338A1 (en) 2006-04-28 2007-11-08 Avexa Limited Integrase inhibitors-3
EP2061472A4 (en) * 2006-05-22 2010-12-22 Thioredoxin Systems Ab BACTERIAL THIOREDOXINE REDUCTASE INHIBITORS AND METHODS OF USING THE SAME
JP2010533729A (ja) 2007-07-17 2010-10-28 プレキシコン,インコーポレーテッド キナーゼ調節のための化合物と方法、及びそのための適応
CN101723932B (zh) 2008-10-31 2013-11-20 北京以岭生物工程技术有限公司 硝基吡啶乙烯亚胺化合物、其药物组合物及其制备方法和用途
WO2010138820A2 (en) 2009-05-28 2010-12-02 President And Fellows Of Harvard College N,n-diarylurea compounds and n,n'-diarylthiourea compounds as inhibitors of translation initiation
KR101906146B1 (ko) 2009-08-17 2018-10-10 메모리얼 슬로안-케터링 캔서 센터 열 충격 단백질 결합 화합물, 조성물, 및 이의 제조 방법 및 사용 방법
JP5850321B2 (ja) 2010-02-10 2016-02-03 公立大学法人横浜市立大学 神経選択的転写抑制因子NRSFに特異的に結合するmSin3Bに結合する化合物の利用
CN102206172B (zh) 2010-03-30 2015-02-25 中国医学科学院医药生物技术研究所 一组取代双芳基化合物及其制备方法和抗病毒应用
WO2012025638A1 (en) 2010-08-27 2012-03-01 Universität des Saarlandes Selective 17beta-hydroxysteroid dehydrogenase type 1 inhibitors
US9539256B2 (en) 2012-02-10 2017-01-10 The Board Of Regents Of The University Of Texas System Modulators of exchange proteins directly activated by cAMP (EPACS)
WO2015006458A1 (en) 2013-07-10 2015-01-15 Boehringer Ingelheim International Gmbh Novel chiral nitrogen-phosphorus ligands and their use for asymmetric hydrogenation of alkenes
CN104672214B (zh) 2013-12-03 2019-04-12 上海翰森生物医药科技有限公司 具有alk抑制活性的化合物及其制备与用途
CN105503827B (zh) 2014-10-11 2019-09-24 上海翰森生物医药科技有限公司 Egfr抑制剂及其制备方法和用途
CN105085483B (zh) 2015-06-04 2019-01-01 湖北生物医药产业技术研究院有限公司 激酶抑制剂及其应用
CN104987324B (zh) 2015-06-04 2018-05-04 湖北生物医药产业技术研究院有限公司 作为alk抑制剂的嘧啶衍生物
GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
AU2018218519B2 (en) 2017-02-07 2021-08-05 Oblique Therapeutics Ab Heteroarylsulfonyl-substituted pyridines and their use in the treatment of cancer
US11168069B2 (en) 2017-02-07 2021-11-09 Oblique Therapeutics Ab Heterocyclylsulfonyl-substituted pyridines and their use in the treatment of cancer
CA3051539A1 (en) 2017-02-07 2018-08-16 Oblique Therapeutics Ab Hydrocarbylsulfonyl-substituted pyridines and their use in the treatment of cancer
MA47450A (fr) * 2017-02-07 2019-12-18 Oblique Therapeutics Ab Sulfinylpyridines et leur utilisation dans le traitement du cancer

Similar Documents

Publication Publication Date Title
JP2020507624A5 (https=)
JP2020506244A5 (https=)
JP2020507625A5 (https=)
JP2020506970A5 (https=)
JP2020533277A5 (https=)
RU2019127896A (ru) Сульфинилпиридины и их применение при лечении рака
JP2019094345A5 (https=)
JP2010539110A5 (https=)
CN110016025A (zh) 一种免疫调节剂
JP2019517487A5 (https=)
JP2008546791A5 (https=)
MX2014015158A (es) Derivados de piridinona y piridazinona.
RU2019128063A (ru) Углеводородсульфонилзамещенные пиридины и их применение при лечении рака
RU2015124002A (ru) Соединения, применяемые в качестве ингибиторов индоламин-2,3-диоксигеназы
RU2018107879A (ru) Пиридины и их применение в лечении рака
JP2012522759A5 (https=)
JP2019512535A5 (https=)
JP2017522277A5 (https=)
JP2016190843A5 (https=)
JP2018529690A5 (https=)
JP2020527173A5 (https=)
EA025863B1 (ru) Карбазолкарбоксамидные соединения
JPWO2014007217A1 (ja) イミダゾオキサジン化合物による抗腫瘍効果増強剤
JP2018532786A5 (https=)
CN116113416A (zh) 四环类衍生物、其制备方法和其医药上的用途