JP2020502271A5 - - Google Patents

Download PDF

Info

Publication number
JP2020502271A5
JP2020502271A5 JP2019553163A JP2019553163A JP2020502271A5 JP 2020502271 A5 JP2020502271 A5 JP 2020502271A5 JP 2019553163 A JP2019553163 A JP 2019553163A JP 2019553163 A JP2019553163 A JP 2019553163A JP 2020502271 A5 JP2020502271 A5 JP 2020502271A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
sequence
antibody
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019553163A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020502271A (ja
JP7350313B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/066661 external-priority patent/WO2018112334A1/en
Publication of JP2020502271A publication Critical patent/JP2020502271A/ja
Publication of JP2020502271A5 publication Critical patent/JP2020502271A5/ja
Priority to JP2022075922A priority Critical patent/JP7401126B2/ja
Application granted granted Critical
Publication of JP7350313B2 publication Critical patent/JP7350313B2/ja
Priority to JP2023203139A priority patent/JP2024026234A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019553163A 2016-12-16 2017-12-15 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法 Active JP7350313B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022075922A JP7401126B2 (ja) 2016-12-16 2022-05-02 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法
JP2023203139A JP2024026234A (ja) 2016-12-16 2023-11-30 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662435509P 2016-12-16 2016-12-16
US62/435,509 2016-12-16
US201762488445P 2017-04-21 2017-04-21
US62/488,445 2017-04-21
US201762588516P 2017-11-20 2017-11-20
US62/588,516 2017-11-20
PCT/US2017/066661 WO2018112334A1 (en) 2016-12-16 2017-12-15 Anti-cub domain-containing protein 1 (cdcp1) antibodies, antibody drug conjugates, and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022075922A Division JP7401126B2 (ja) 2016-12-16 2022-05-02 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法

Publications (3)

Publication Number Publication Date
JP2020502271A JP2020502271A (ja) 2020-01-23
JP2020502271A5 true JP2020502271A5 (US07794700-20100914-C00152.png) 2021-02-04
JP7350313B2 JP7350313B2 (ja) 2023-09-26

Family

ID=62559349

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019553163A Active JP7350313B2 (ja) 2016-12-16 2017-12-15 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法
JP2022075922A Active JP7401126B2 (ja) 2016-12-16 2022-05-02 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法
JP2023203139A Pending JP2024026234A (ja) 2016-12-16 2023-11-30 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022075922A Active JP7401126B2 (ja) 2016-12-16 2022-05-02 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法
JP2023203139A Pending JP2024026234A (ja) 2016-12-16 2023-11-30 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法

Country Status (7)

Country Link
US (4) US11702481B2 (US07794700-20100914-C00152.png)
EP (1) EP3554544A4 (US07794700-20100914-C00152.png)
JP (3) JP7350313B2 (US07794700-20100914-C00152.png)
CN (2) CN118562004A (US07794700-20100914-C00152.png)
CA (1) CA3047115A1 (US07794700-20100914-C00152.png)
MA (1) MA50134A (US07794700-20100914-C00152.png)
WO (1) WO2018112334A1 (US07794700-20100914-C00152.png)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118562004A (zh) * 2016-12-16 2024-08-30 蓝鳍生物医药公司 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法
JP7440509B2 (ja) * 2018-11-09 2024-02-28 ベス イスラエル デアコネス メディカル センター Cdcp1-標的化療法
CN113329770A (zh) * 2019-01-24 2021-08-31 中外制药株式会社 新型癌抗原及所述抗原的抗体
CN113853216A (zh) * 2019-02-01 2021-12-28 肿瘤学研究所基金会(Ior) 治疗去势抵抗性前列腺癌的方法
AU2020377402A1 (en) * 2019-11-06 2022-06-23 Commonwealth Scientific And Industrial Research Organisation Binding proteins to CUB domain-containing protein (CDCP1)
CN118440202A (zh) * 2019-12-27 2024-08-06 凯奥目生物科学株式会社 抗cdcp1抗体
WO2022212876A1 (en) * 2021-04-02 2022-10-06 The Regents Of The University Of California Antibodies against cleaved cdcp1 and uses thereof
AU2022337286A1 (en) * 2021-09-03 2024-02-29 Novarock Biotherapeutics, Ltd. Bispecific binding proteins that bind cd137 and a tumor associated antigen
LU500787B1 (en) 2021-10-26 2023-04-27 Univ Hamburg Eppendorf Uke Isolation and detection of cdcp1 positive circulating tumor cells
WO2023246701A1 (zh) * 2022-06-20 2023-12-28 四川汇宇制药股份有限公司 一种抗体及其用途
WO2024013724A1 (en) 2022-07-15 2024-01-18 Pheon Therapeutics Ltd Antibody-drug conjugates
KR20240057529A (ko) * 2022-10-24 2024-05-03 주식회사 노벨티노빌리티 신규 항-cdcp1 항체 및 이의 용도
WO2024127366A1 (en) * 2022-12-16 2024-06-20 Pheon Therapeutics Ltd Antibodies to cub domain-containing protein 1 (cdcp1) and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103275221B (zh) 1996-02-09 2016-08-17 艾伯维生物技术有限公司 结合人TNFα的人抗体
US6245898B1 (en) 1998-06-15 2001-06-12 The Research Foundation Of State University Of New York Monoclonal antibodies that recognize antigens associated with tumor metastasis
DE10242146A1 (de) 2002-09-04 2004-03-18 Eberhard-Karls-Universität Tübingen Universitätsklinikum Antikörper zur Identifizierung und/oder Isolierung von hämatopoetischen Stammzellen
CA2787820A1 (en) * 2003-02-19 2004-09-02 Novartis Ag Glycoprotein antigen sima135 expressed in metastatic human tumor cells
GB0324656D0 (en) 2003-10-22 2003-11-26 Celltech R&D Ltd A protein involved in ovarian cancer
US20080008719A1 (en) 2004-07-10 2008-01-10 Bowdish Katherine S Methods and compositions for the treatment of prostate cancer
JP2007112734A (ja) 2005-10-19 2007-05-10 Chugai Pharmaceut Co Ltd 抗cdcp1抗体を含有する癌細胞増殖抑制剤
DK2769992T3 (da) 2006-10-02 2021-03-22 Regeneron Pharma Humane antistoffer med høj affinitet for human IL-4-receptor
EP2447719B1 (en) 2007-02-26 2016-08-24 Oxford BioTherapeutics Ltd Proteins
US20100233154A1 (en) * 2008-10-08 2010-09-16 Medimmune Limited Targeted binding agents directed to heparanase and uses thereof 463
TWI412375B (zh) 2009-08-28 2013-10-21 Roche Glycart Ag 人類化抗cdcp1抗體
TW201113037A (en) * 2009-08-28 2011-04-16 Hoffmann La Roche Antibodies against CDCP1 for the treatment of cancer
GB201001791D0 (en) 2010-02-03 2010-03-24 Ucb Pharma Sa Process for obtaining antibodies
US20110214205A1 (en) 2010-02-26 2011-09-01 Monsanto Technology Llc. Isolated Novel Nucleic Acid and Protein Molecules from Foxtail Millet and Methods of Using Those Molecules to Generate Transgenic Plants with Enhanced Agronomic Traits
US9574002B2 (en) 2011-06-06 2017-02-21 Amgen Inc. Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
EP2721071A4 (en) 2011-06-14 2015-01-21 Us Health TEM8 ANTIBODIES, CONJUGATES THEREOF AND THEIR USE
HUE033245T2 (hu) 2011-12-19 2017-11-28 Synimmune Gmbh Bispecifikus ellenanyag molekula
US20140363448A1 (en) 2012-01-02 2014-12-11 Novartis Ag Cdcp1 and breast cancer
US10377817B2 (en) 2013-03-14 2019-08-13 Regeneron Pharmaceuticals, Inc. Human antibodies to GREM1
WO2015082446A1 (en) 2013-12-02 2015-06-11 F. Hoffmann-La Roche Ag Treatment of cancer using an anti-cdcp1 antibody and a taxane
US10815469B2 (en) 2014-06-11 2020-10-27 Molecular Templates, Inc. Cell-targeting molecules comprising protease-cleavage resistant, Shiga toxin A subunit effector polypeptides and carboxy-terminal moieties
EP3167288B1 (en) 2014-07-11 2021-10-20 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for diagnosing hematological cancers
EP3029067A1 (en) 2014-12-01 2016-06-08 Deutsches Krebsforschungszentrum Use of blocking-reagents for reducing unspecific T cell-activation
SG10201912666PA (en) * 2015-04-13 2020-02-27 Pfizer Chimeric antigen receptors targeting b-cell maturation antigen
CN118562004A (zh) * 2016-12-16 2024-08-30 蓝鳍生物医药公司 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法

Similar Documents

Publication Publication Date Title
JP2020502271A5 (US07794700-20100914-C00152.png)
JP2022101693A5 (US07794700-20100914-C00152.png)
JP2020527355A5 (US07794700-20100914-C00152.png)
JP2020501531A5 (US07794700-20100914-C00152.png)
JP2018070648A5 (US07794700-20100914-C00152.png)
ES2773504T3 (es) Nuevo polipéptido que tiene afinidad por PD-L1
JP2017535257A5 (US07794700-20100914-C00152.png)
HRP20201022T1 (hr) Potpuno ljudsko antitijelo protiv ljudskog cd137 i njegova uporaba
JP2017186337A5 (US07794700-20100914-C00152.png)
JP2010535713A5 (US07794700-20100914-C00152.png)
JP2017048240A5 (US07794700-20100914-C00152.png)
JP2018504105A5 (US07794700-20100914-C00152.png)
JP2010531140A5 (US07794700-20100914-C00152.png)
HRP20160190T1 (hr) Protutijela anti-igf
JP2020514310A5 (US07794700-20100914-C00152.png)
JP2018500014A5 (US07794700-20100914-C00152.png)
JP2015534579A5 (US07794700-20100914-C00152.png)
JP2018536632A5 (ja) B7‐h3に特異的に結合する分子及びpd‐1に特異的に結合する分子
JP2016537383A5 (US07794700-20100914-C00152.png)
JP2017519759A5 (US07794700-20100914-C00152.png)
JP2015534577A5 (US07794700-20100914-C00152.png)
JP2016503295A5 (US07794700-20100914-C00152.png)
JP2018516966A5 (US07794700-20100914-C00152.png)
IL278574B1 (en) Compounds acting on glycans and methods of using them
CA2595610A1 (en) Antibodies directed to angiopoietin-2 and uses thereof