JP2020502104A5 - - Google Patents

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Publication number
JP2020502104A5
JP2020502104A5 JP2019531589A JP2019531589A JP2020502104A5 JP 2020502104 A5 JP2020502104 A5 JP 2020502104A5 JP 2019531589 A JP2019531589 A JP 2019531589A JP 2019531589 A JP2019531589 A JP 2019531589A JP 2020502104 A5 JP2020502104 A5 JP 2020502104A5
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JP
Japan
Prior art keywords
sequence
chain
protein
selenocysteine
residues
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Application number
JP2019531589A
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English (en)
Japanese (ja)
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JP7186400B2 (ja
JP2020502104A (ja
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Priority claimed from PCT/US2017/049354 external-priority patent/WO2018045018A1/en
Publication of JP2020502104A publication Critical patent/JP2020502104A/ja
Publication of JP2020502104A5 publication Critical patent/JP2020502104A5/ja
Priority to JP2022184852A priority Critical patent/JP7378106B2/ja
Application granted granted Critical
Publication of JP7186400B2 publication Critical patent/JP7186400B2/ja
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JP2019531589A 2016-08-30 2017-08-30 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造 Active JP7186400B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022184852A JP7378106B2 (ja) 2016-08-30 2022-11-18 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662381316P 2016-08-30 2016-08-30
US62/381,316 2016-08-30
US201762537986P 2017-07-28 2017-07-28
US62/537,986 2017-07-28
PCT/US2017/049354 WO2018045018A1 (en) 2016-08-30 2017-08-30 Production of seleno-biologics in genomically recoded organisms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022184852A Division JP7378106B2 (ja) 2016-08-30 2022-11-18 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造

Publications (3)

Publication Number Publication Date
JP2020502104A JP2020502104A (ja) 2020-01-23
JP2020502104A5 true JP2020502104A5 (enExample) 2020-10-08
JP7186400B2 JP7186400B2 (ja) 2022-12-09

Family

ID=61301655

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019531589A Active JP7186400B2 (ja) 2016-08-30 2017-08-30 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造
JP2022184852A Active JP7378106B2 (ja) 2016-08-30 2022-11-18 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022184852A Active JP7378106B2 (ja) 2016-08-30 2022-11-18 ゲノム的に再コードした生物におけるセレノ-生物製剤の製造

Country Status (6)

Country Link
US (1) US11492650B2 (enExample)
EP (1) EP3506945A4 (enExample)
JP (2) JP7186400B2 (enExample)
CN (1) CN109803679A (enExample)
CA (1) CA3034701A1 (enExample)
WO (1) WO2018045018A1 (enExample)

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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
WO2017117464A1 (en) 2015-12-30 2017-07-06 Kodiak Sciences Inc. Antibodies and conjugates thereof
US11542332B2 (en) 2016-03-26 2023-01-03 Bioatla, Inc. Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof
CN109844105A (zh) 2016-07-11 2019-06-04 得克萨斯州大学系统董事会 包含硒代半胱氨酸的重组多肽及其产生方法
BR112020017872A2 (pt) 2018-03-02 2020-12-22 Kodiak Sciences Inc. Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos
JP7384906B2 (ja) * 2018-07-09 2023-11-21 ジーアールオー・バイオサイエンシズ・インコーポレイテッド 非標準アミノ酸含有組成物とその使用
CN114144426A (zh) * 2019-04-19 2022-03-04 印地安纳大学理事会 餐时或基础胰岛素类似物通过内部二硒桥的稳定化
WO2021072265A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
AU2020398327A1 (en) 2019-12-03 2022-07-14 Evotec International Gmbh Interferon-associated antigen binding proteins and uses thereof
US11179473B2 (en) 2020-02-21 2021-11-23 Silverback Therapeutics, Inc. Nectin-4 antibody conjugates and uses thereof
CN113512116B (zh) * 2020-04-10 2022-09-20 苏州普乐康医药科技有限公司 一种抗igf-1r抗体及其应用
JP2023545520A (ja) 2020-10-14 2023-10-30 ビリジアン セラピューティクス, インコーポレイテッド 甲状腺眼疾患を治療するための組成物及び方法
WO2023019171A1 (en) 2021-08-10 2023-02-16 Viridian Therapeutics, Inc. Compositions, doses, and methods for treatment of thyroid eye disease
CN118076644A (zh) * 2021-09-30 2024-05-24 正大天晴药业集团股份有限公司 针对免疫检查点的双特异性抗体

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US6849417B1 (en) * 1998-04-06 2005-02-01 The United States Of America As Represented By The Department Of Health And Human Services Mammalian selenoprotein differentially expressed in tumor cells
AU6987200A (en) 1999-08-16 2001-03-13 Karolinska Innovations Ab Methods and means for selenoprotein expression
WO2007075438A2 (en) * 2005-12-15 2007-07-05 Codon Devices, Inc. Polypeptides comprising unnatural amino acids, methods for their production and uses therefor
WO2009043051A2 (en) 2007-09-27 2009-04-02 Biogen Idec Ma Inc. Cd23 binding molecules and methods of use thereof
KR101656107B1 (ko) * 2007-11-20 2016-09-08 암브룩스, 인코포레이티드 변형된 인슐린 폴리펩티드 및 이의 용도
AU2012216723B2 (en) * 2007-11-20 2014-08-28 Ambrx, Inc. Modified insulin polypeptides and their uses
JP5572972B2 (ja) * 2009-03-16 2014-08-20 Jnc株式会社 インスリン分泌促進剤などの薬物のスクリーニング方法
US20140024592A1 (en) * 2010-09-08 2014-01-23 Howard Florey Institute Of Experimental Physiology And Medicine Modified Relaxin Polypeptides
MX2013008736A (es) * 2011-01-28 2013-11-22 Ca Nat Research Council Diseño de dominios de inmunoglobulina.
DK2717898T3 (en) 2011-06-10 2019-03-25 Bioverativ Therapeutics Inc COAGULATING COMPOUNDS AND PROCEDURES FOR USE THEREOF
US10240158B2 (en) 2011-07-11 2019-03-26 Yale University Compositions and methods for making selenocysteine containing polypeptides
US9464288B2 (en) 2011-07-11 2016-10-11 Yale University Compositions and methods for making selenocysteine containing polypeptides
US10876142B2 (en) 2011-07-11 2020-12-29 Yale University Compositions and methods for making selenocysteine containing polypeptides
EP2968552B1 (en) 2013-03-14 2020-03-11 The Scripps Research Institute Targeting agent antibody conjugates and uses thereof
US20150050682A1 (en) 2013-08-15 2015-02-19 University Of Vermont And State Agricultural College Direct assay of thioredoxin reductase activity
WO2015066543A1 (en) * 2013-11-01 2015-05-07 Board Of Regents, The University Of Texas System Targeting her2 and her3 with bispecific antibodies in cancerous cells
US10118950B2 (en) 2014-08-30 2018-11-06 Northwestern University Platforms for cell-free protein synthesis comprising extracts from genomically recoded E. coli strains having genetic knock-out mutations in release factor 1 (RF-1) and endA
WO2016172269A2 (en) * 2015-04-20 2016-10-27 University Of Utah Research Foundation Insulin analogs having shortened b chain peptides and associated methods
CN105111304B (zh) * 2015-09-30 2018-12-14 山东阿华生物药业有限公司 重组人胰岛素前体的纯化和酶切转换方法
US10557160B2 (en) 2015-12-15 2020-02-11 Board Of Regents, The University Of Texas System Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same
CN109844105A (zh) * 2016-07-11 2019-06-04 得克萨斯州大学系统董事会 包含硒代半胱氨酸的重组多肽及其产生方法
AU2017298565B2 (en) 2016-07-22 2021-08-19 The Walter And Eliza Hall Institute Of Medical Research Insulin analogs
IL264330B2 (en) * 2016-07-22 2024-05-01 Univ Utah Res Found An insulin analog, pharmaceutical composition comprising it and its uses
CN114144426A (zh) 2019-04-19 2022-03-04 印地安纳大学理事会 餐时或基础胰岛素类似物通过内部二硒桥的稳定化

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