JP2020502054A - 抗線維化療法を投与する方法 - Google Patents

抗線維化療法を投与する方法 Download PDF

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Publication number
JP2020502054A
JP2020502054A JP2019524383A JP2019524383A JP2020502054A JP 2020502054 A JP2020502054 A JP 2020502054A JP 2019524383 A JP2019524383 A JP 2019524383A JP 2019524383 A JP2019524383 A JP 2019524383A JP 2020502054 A JP2020502054 A JP 2020502054A
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JP
Japan
Prior art keywords
compound
subject
food
administration
ppi
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Pending
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JP2019524383A
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English (en)
Japanese (ja)
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JP2020502054A5 (enExample
Inventor
リン パン，
リン パン，
ドロシー ジィー−ウィン チュン，
ドロシー ジィー−ウィン チュン，
ジェフリー マーク ハリス，
ジェフリー マーク ハリス，
インディアナ ストロンボム，
インディアナ ストロンボム，
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Genentech Inc
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Genentech Inc
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Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2020502054A publication Critical patent/JP2020502054A/ja
Publication of JP2020502054A5 publication Critical patent/JP2020502054A5/ja
Priority to JP2022015514A priority Critical patent/JP7495951B2/ja
Priority to JP2023118969A priority patent/JP2023139157A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2019524383A 2016-11-30 2017-11-29 抗線維化療法を投与する方法 Pending JP2020502054A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022015514A JP7495951B2 (ja) 2016-11-30 2022-02-03 抗線維化療法を投与する方法
JP2023118969A JP2023139157A (ja) 2016-11-30 2023-07-21 抗線維化療法を投与する方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662428163P 2016-11-30 2016-11-30
US62/428,163 2016-11-30
US201662432425P 2016-12-09 2016-12-09
US62/432,425 2016-12-09
PCT/US2017/063549 WO2018102323A1 (en) 2016-11-30 2017-11-29 Methods of administering anti-fibrotic therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022015514A Division JP7495951B2 (ja) 2016-11-30 2022-02-03 抗線維化療法を投与する方法

Publications (2)

Publication Number Publication Date
JP2020502054A true JP2020502054A (ja) 2020-01-23
JP2020502054A5 JP2020502054A5 (enExample) 2021-01-14

Family

ID=60655162

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019524383A Pending JP2020502054A (ja) 2016-11-30 2017-11-29 抗線維化療法を投与する方法
JP2022015514A Active JP7495951B2 (ja) 2016-11-30 2022-02-03 抗線維化療法を投与する方法
JP2023118969A Withdrawn JP2023139157A (ja) 2016-11-30 2023-07-21 抗線維化療法を投与する方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022015514A Active JP7495951B2 (ja) 2016-11-30 2022-02-03 抗線維化療法を投与する方法
JP2023118969A Withdrawn JP2023139157A (ja) 2016-11-30 2023-07-21 抗線維化療法を投与する方法

Country Status (11)

Country Link
US (3) US11207304B2 (enExample)
EP (2) EP3548025A1 (enExample)
JP (3) JP2020502054A (enExample)
KR (3) KR20230129628A (enExample)
CN (1) CN110087651A (enExample)
AU (3) AU2017366881A1 (enExample)
CA (2) CA3045455A1 (enExample)
IL (3) IL299447A (enExample)
MX (3) MX2019006143A (enExample)
TW (3) TWI891129B (enExample)
WO (1) WO2018102323A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI891129B (zh) 2016-11-30 2025-07-21 美商基因科技公司 投與抗纖維化療法之方法
CN114129517A (zh) * 2020-09-03 2022-03-04 苏州爱科百发生物医药技术有限公司 一种ak3287制剂及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015153683A1 (en) * 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR092742A1 (es) * 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
TWI891129B (zh) 2016-11-30 2025-07-21 美商基因科技公司 投與抗纖維化療法之方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015153683A1 (en) * 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
岡山医学会雑誌, vol. 127, JPN6021034577, 2015, pages 245 - 249, ISSN: 0004784605 *

Also Published As

Publication number Publication date
EP4470624A3 (en) 2025-01-08
AU2025238129A1 (en) 2025-10-23
AU2017366881A1 (en) 2019-05-30
EP4470624A2 (en) 2024-12-04
KR20220139450A (ko) 2022-10-14
WO2018102323A1 (en) 2018-06-07
TW201825093A (zh) 2018-07-16
AU2023263548B2 (en) 2025-10-16
US20240197693A1 (en) 2024-06-20
TW202539656A (zh) 2025-10-16
IL289544A (en) 2022-03-01
AU2023263548A1 (en) 2023-11-30
TWI891129B (zh) 2025-07-21
IL289544B2 (en) 2023-06-01
TWI826361B (zh) 2023-12-21
JP2022058873A (ja) 2022-04-12
TW202412795A (zh) 2024-04-01
MX2020011766A (es) 2020-11-24
US11925624B2 (en) 2024-03-12
US11207304B2 (en) 2021-12-28
IL266480A (en) 2019-07-31
KR20190089862A (ko) 2019-07-31
CN110087651A (zh) 2019-08-02
JP7495951B2 (ja) 2024-06-05
US12310951B2 (en) 2025-05-27
KR20230129628A (ko) 2023-09-08
CA3247781A1 (en) 2025-07-09
IL299447A (en) 2023-02-01
US20190321344A1 (en) 2019-10-24
US20220184046A1 (en) 2022-06-16
KR102575344B1 (ko) 2023-09-06
CA3045455A1 (en) 2018-06-07
MX2023003924A (es) 2023-04-26
JP2023139157A (ja) 2023-10-03
MX2019006143A (es) 2019-10-17
EP3548025A1 (en) 2019-10-09

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