JP2020500882A5 - - Google Patents
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- Publication number
- JP2020500882A5 JP2020500882A5 JP2019529890A JP2019529890A JP2020500882A5 JP 2020500882 A5 JP2020500882 A5 JP 2020500882A5 JP 2019529890 A JP2019529890 A JP 2019529890A JP 2019529890 A JP2019529890 A JP 2019529890A JP 2020500882 A5 JP2020500882 A5 JP 2020500882A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- transdermal patch
- treprostinil
- patch
- adhesive layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 17
- 229940079593 drug Drugs 0.000 claims 15
- PAJMKGZZBBTTOY-ZFORQUDYSA-N treprostinil Chemical compound C1=CC=C(OCC(O)=O)C2=C1C[C@@H]1[C@@H](CC[C@@H](O)CCCCC)[C@H](O)C[C@@H]1C2 PAJMKGZZBBTTOY-ZFORQUDYSA-N 0.000 claims 10
- 229960005032 treprostinil Drugs 0.000 claims 10
- 239000010410 layer Substances 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 7
- 239000011159 matrix material Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 239000012790 adhesive layer Substances 0.000 claims 5
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 3
- 206010019280 Heart failures Diseases 0.000 claims 2
- 206010040943 Skin Ulcer Diseases 0.000 claims 2
- 230000007654 ischemic lesion Effects 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 206010007559 Cardiac failure congestive Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 239000004821 Contact adhesive Substances 0.000 claims 1
- 208000003790 Foot Ulcer Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000035901 Ischaemic ulcer Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 208000018262 Peripheral vascular disease Diseases 0.000 claims 1
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 claims 1
- 208000001647 Renal Insufficiency Diseases 0.000 claims 1
- 208000034841 Thrombotic Microangiopathies Diseases 0.000 claims 1
- 206010058990 Venous occlusion Diseases 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 230000036523 atherogenesis Effects 0.000 claims 1
- 150000001735 carboxylic acids Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 208000023589 ischemic disease Diseases 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 201000006370 kidney failure Diseases 0.000 claims 1
- 208000030175 lameness Diseases 0.000 claims 1
- 239000010985 leather Substances 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 230000007310 pathophysiology Effects 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 208000002815 pulmonary hypertension Diseases 0.000 claims 1
- 230000008085 renal dysfunction Effects 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 231100000245 skin permeability Toxicity 0.000 claims 1
- 231100000019 skin ulcer Toxicity 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 239000005526 vasoconstrictor agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023114183A JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430053P | 2016-12-05 | 2016-12-05 | |
| US62/430,053 | 2016-12-05 | ||
| PCT/US2017/064612 WO2018106632A1 (en) | 2016-12-05 | 2017-12-05 | Dermal and transdermal administration of treprostinil and salts thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114183A Division JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020500882A JP2020500882A (ja) | 2020-01-16 |
| JP2020500882A5 true JP2020500882A5 (https=) | 2021-01-07 |
Family
ID=60782377
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529890A Pending JP2020500882A (ja) | 2016-12-05 | 2017-12-05 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
| JP2023114183A Pending JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114183A Pending JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190290597A1 (https=) |
| EP (1) | EP3548010A1 (https=) |
| JP (2) | JP2020500882A (https=) |
| KR (2) | KR20190109399A (https=) |
| CN (1) | CN110381930A (https=) |
| CA (1) | CA3045917A1 (https=) |
| IL (1) | IL267046A (https=) |
| WO (1) | WO2018106632A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3712142B1 (en) | 2013-01-11 | 2022-07-06 | Corsair Pharma, Inc. | Prodrugs of treprostinil |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| US11607026B2 (en) * | 2014-05-30 | 2023-03-21 | Johnson & Johnson Consumer Inc. | Device for delivery of skin care composition |
| US9394227B1 (en) | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| US9643911B2 (en) | 2015-06-17 | 2017-05-09 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| WO2019218006A1 (en) * | 2018-05-14 | 2019-11-21 | Butterworth Building | Oil therapy method and device |
| AU2019344541B2 (en) * | 2018-09-18 | 2022-01-06 | Eli Lilly And Company | Erbumine salt of treprostinil |
| IL300709A (en) * | 2020-08-16 | 2023-04-01 | Ofer Spottheim | Medical bandage |
| JP2024094445A (ja) * | 2021-03-17 | 2024-07-10 | 国立大学法人九州大学 | 経皮吸収剤 |
| US20230026731A1 (en) * | 2021-03-31 | 2023-01-26 | Mycrodose Therapeutics Inc. | Transdermal system, formulation, and method for the therapeutic administration of a psychedelic agent |
| CN113842377A (zh) * | 2021-08-11 | 2021-12-28 | 杭州师范大学 | 一种经皮递送榄香烯的pdms微针贴片及其制备方法 |
| US20250017870A1 (en) * | 2021-11-15 | 2025-01-16 | Artience Co., Ltd. | Adhesive patch containing selexipag as active ingredient |
| CA3236242A1 (en) * | 2021-12-13 | 2023-06-22 | Stephen Welsh | Adhesive bandage system for medication delivery and indication of procedure location |
| CN118765196A (zh) * | 2022-01-27 | 2024-10-11 | Lts罗曼治疗系统股份公司 | 用于透皮施用赛乐西帕的透皮治疗系统 |
| KR20250002687A (ko) * | 2022-04-29 | 2025-01-07 | 자오커 파마슈티컬 (광저우) 컴퍼니., 리미티드 | 트레프로스티닐 소프트 미스트 흡입제 |
| WO2024015602A1 (en) * | 2022-07-15 | 2024-01-18 | Aso Llc | Therapeutic foot patch for cough treatment |
| CN118178292B (zh) * | 2024-03-07 | 2024-10-01 | 广州博科化妆品有限公司 | 一种含有水蛭素和植物提取物的防脱洗发露及其制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3598122A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US4144317A (en) | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US4262003A (en) | 1975-12-08 | 1981-04-14 | Alza Corporation | Method and therapeutic system for administering scopolamine transdermally |
| US4201211A (en) | 1977-07-12 | 1980-05-06 | Alza Corporation | Therapeutic system for administering clonidine transdermally |
| US4379454A (en) | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
| GB9011588D0 (en) * | 1990-05-24 | 1990-07-11 | Wellcome Found | Prostaglandin analogues for use in medicine |
| US5234690A (en) | 1991-08-23 | 1993-08-10 | Cygnus Therapeutic Systems | Transdermal drug delivery device using an unfilled microporous membrane to achieve delayed onset |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| US6682757B1 (en) | 2000-11-16 | 2004-01-27 | Euro-Celtique, S.A. | Titratable dosage transdermal delivery system |
| CN101265226B (zh) | 2003-05-22 | 2013-04-24 | 联合治疗公司 | 化合物和释放前列环素类似物的方法 |
| US20070269379A1 (en) | 2003-07-23 | 2007-11-22 | Samir Mitragotri | Penetration Enhancer Combinations for Transdermal Delivery |
| CN1917866B (zh) * | 2003-12-16 | 2010-12-15 | 联合治疗公司 | 曲前列环素或它的衍生物，或其药学上可接受的盐在制备治疗和预防缺血性损害的药物中的用途 |
| ATE462427T1 (de) * | 2004-04-12 | 2010-04-15 | United Therapeutics Corp | Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren |
| WO2009124096A1 (en) * | 2008-03-31 | 2009-10-08 | Altea Therapeutics Corporation | Permeant delivery system and methods for use thereof |
| US8350079B2 (en) | 2008-05-08 | 2013-01-08 | United Therapeutics Corporation | Treprostinil formulation |
| US20110294815A1 (en) | 2008-06-27 | 2011-12-01 | Harbeson Scott L | Prostacyclin analogs |
| US9327105B2 (en) * | 2010-03-26 | 2016-05-03 | Itrace Biomedical Inc. | Active transdermal drug delivery system and the method thereof |
| CN103193627B (zh) | 2012-01-10 | 2016-04-20 | 上海天伟生物制药有限公司 | 一种前列腺素类似物的晶型及其制备方法和用途 |
| CN103193626B (zh) | 2012-01-10 | 2016-05-11 | 上海天伟生物制药有限公司 | 一种前列腺素类似物的晶型及其制备方法和用途 |
| ES2869701T3 (es) * | 2012-08-01 | 2021-10-25 | United Therapeutics Corp | Tratamiento de hipertensión arterial pulmonar con células progenitoras endoteliales tratadas con prostaciclina |
| US9505737B2 (en) * | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| EP2970091A4 (en) | 2013-03-14 | 2017-02-08 | United Therapeutics Corporation | Solid forms of treprostinil |
| US9394227B1 (en) * | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
-
2017
- 2017-12-05 US US16/465,683 patent/US20190290597A1/en not_active Abandoned
- 2017-12-05 KR KR1020197018666A patent/KR20190109399A/ko not_active Ceased
- 2017-12-05 EP EP17818389.3A patent/EP3548010A1/en active Pending
- 2017-12-05 CA CA3045917A patent/CA3045917A1/en active Pending
- 2017-12-05 JP JP2019529890A patent/JP2020500882A/ja active Pending
- 2017-12-05 WO PCT/US2017/064612 patent/WO2018106632A1/en not_active Ceased
- 2017-12-05 KR KR1020237026190A patent/KR20230119035A/ko not_active Ceased
- 2017-12-05 CN CN201780084968.9A patent/CN110381930A/zh active Pending
-
2019
- 2019-06-02 IL IL267046A patent/IL267046A/en unknown
-
2023
- 2023-07-12 JP JP2023114183A patent/JP2023134620A/ja active Pending
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