JP2020500871A5 - - Google Patents
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- JP2020500871A5 JP2020500871A5 JP2019529240A JP2019529240A JP2020500871A5 JP 2020500871 A5 JP2020500871 A5 JP 2020500871A5 JP 2019529240 A JP2019529240 A JP 2019529240A JP 2019529240 A JP2019529240 A JP 2019529240A JP 2020500871 A5 JP2020500871 A5 JP 2020500871A5
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- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound according
- compound
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022193738A JP2023029957A (ja) | 2016-11-30 | 2022-12-02 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662428492P | 2016-11-30 | 2016-11-30 | |
| US62/428,492 | 2016-11-30 | ||
| US201762553313P | 2017-09-01 | 2017-09-01 | |
| US62/553,313 | 2017-09-01 | ||
| PCT/US2017/064081 WO2018102616A1 (en) | 2016-11-30 | 2017-11-30 | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022193738A Division JP2023029957A (ja) | 2016-11-30 | 2022-12-02 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500871A JP2020500871A (ja) | 2020-01-16 |
| JP2020500871A5 true JP2020500871A5 (https=) | 2021-01-21 |
| JP7649624B2 JP7649624B2 (ja) | 2025-03-21 |
Family
ID=62241919
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529240A Active JP7649624B2 (ja) | 2016-11-30 | 2017-11-30 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
| JP2022193738A Pending JP2023029957A (ja) | 2016-11-30 | 2022-12-02 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022193738A Pending JP2023029957A (ja) | 2016-11-30 | 2022-12-02 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20200317745A1 (https=) |
| EP (1) | EP3548012A4 (https=) |
| JP (2) | JP7649624B2 (https=) |
| CN (1) | CN110114065A (https=) |
| AU (1) | AU2017367699B2 (https=) |
| BR (1) | BR112019011070A2 (https=) |
| CA (1) | CA3045458A1 (https=) |
| IL (1) | IL266977B2 (https=) |
| MX (1) | MX2019006189A (https=) |
| WO (1) | WO2018102616A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018102616A1 (en) * | 2016-11-30 | 2018-06-07 | Purdue Research Foundation | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
| WO2019232285A1 (en) | 2018-05-30 | 2019-12-05 | Purdue Research Foundation | Targeting anabolic drugs for accelerated fracture repair |
| CN110551201B (zh) * | 2019-08-26 | 2020-04-28 | 杭州彗搏科技有限公司 | 一种新型骨形成蛋白2来源的环肽、制备方法及其应用 |
| MX2022002979A (es) * | 2019-09-12 | 2022-06-16 | Radius Health Inc | Metodos para mejorar la fusion vertebral con abaloparatida. |
| CN112646042A (zh) * | 2019-10-10 | 2021-04-13 | 陕西麦科奥特科技有限公司 | 活性多肽化合物 |
| AU2021338361A1 (en) * | 2020-09-03 | 2023-04-06 | Chen, Irvin S.Y | Soluble alkaline phosphatase constructs and expression vectors including a polynucleotide encoding for soluble alkaline phosphatase constructs |
| WO2022093373A1 (en) * | 2020-10-26 | 2022-05-05 | Purdue Research Foundation | Compounds,compositions and methods of use to treat bone fractures |
| WO2022093374A1 (en) * | 2020-10-26 | 2022-05-05 | Purdue Research Foundation | Compounds,compositions and methods of use to treat spinal fusions |
| AU2022205801A1 (en) * | 2021-01-05 | 2023-07-13 | Radius Health, Inc. | Treatment of long bone fractures with abaloparatide |
| US20250295725A1 (en) * | 2022-01-14 | 2025-09-25 | Purdue Research Foundation | Bone targeted treatment in osteogenesis imperfecta |
| EP4719459A1 (en) * | 2023-06-01 | 2026-04-08 | Radius Health, Inc. | Methods for identification and quantitation of abaloparatide and related peptide impurities |
| WO2025019691A1 (en) * | 2023-07-19 | 2025-01-23 | Zymeron Corporation | Drug conjugates for bone marrow protection |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9103791A (en) * | 1990-12-21 | 1992-07-22 | Allelix Biopharmaceuticals Inc. | Oxidation resistant variants of parathyroid hormone |
| WO1995002610A1 (en) * | 1993-07-13 | 1995-01-26 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| JP4394279B2 (ja) * | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
| US7057012B1 (en) * | 1998-12-31 | 2006-06-06 | The General Hospital Corporation | PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules |
| JP2000327583A (ja) | 1999-05-17 | 2000-11-28 | Medei Sci Puraningu:Kk | 骨指向性ホルモン誘導体 |
| WO2004062588A2 (en) * | 2003-01-06 | 2004-07-29 | University Of Utah | Water-soluble polymeric bone-targeting drug delivery system |
| DE602005027461D1 (de) | 2004-04-21 | 2011-05-26 | Enobia Pharma Inc | Konjugate zur zuführung an knochen und verfahren zu deren verwendung beim hinführen von proteinen zum knochen |
| US7863238B2 (en) | 2004-06-10 | 2011-01-04 | Saint Louis University | Proteins with an attached short peptide of acidic amino acids |
| US20110046059A1 (en) * | 2005-09-06 | 2011-02-24 | Zelos Therapeutics, Inc. | Pharmaceutically acceptable formulations/compositions for peptidyl drugs |
| KR101512377B1 (ko) | 2006-10-03 | 2015-04-28 | 라디우스 헬쓰, 인코포레이티드 | 골 아나볼릭 단백질을 위한 약물 전달 방법 |
| US7803770B2 (en) * | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| WO2008124166A2 (en) | 2007-04-09 | 2008-10-16 | The Board Of Trustees Of The University Of Arkansas | Fusion proteins of collagen-binding domain and parathyroid hormone |
| PT2662448T (pt) | 2007-05-11 | 2017-03-29 | Alexion Pharma Inc | Fosfatase alcalina dirigida ao osso, kits e métodos para a utilização da mesma |
| EP2303288A4 (en) * | 2008-05-22 | 2015-04-22 | Univ Ramot | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESE MEDIUM AND ITS USE IN THE TREATMENT AND CONTROL OF ILLNESSES RELATED TO BONE |
| WO2012111852A1 (ja) * | 2011-02-17 | 2012-08-23 | 帝人ファーマ株式会社 | 椎体骨折治療剤及びその評価方法 |
| BR112013027153A2 (pt) | 2011-04-22 | 2016-11-29 | 3M Innovative Properties Co | método de aplicação de fármaco para pth, pthrp e peptídeos relacionados |
| CN102824647B (zh) * | 2011-06-13 | 2014-07-23 | 香港中文大学 | 基于小核酸药物成骨治疗的骨靶向递送系统及其制备方法 |
| CA2883707A1 (en) * | 2012-08-28 | 2014-03-06 | The Governors Of The University Of Alberta | Parathyroid hormone, insulin, and related peptides conjugated to bone targeting moieties and methods of making and using thereof |
| WO2014209893A2 (en) | 2013-06-23 | 2014-12-31 | Wisconsin Alumni Research Foundation | Alpha-/beta-polypeptide analogs of parathyroid hormone (pth) and method of using same |
| CA2977812A1 (en) * | 2015-03-03 | 2016-09-09 | Radius Health, Inc. | Uses of pthrp analogue in reducing fracture risk |
| WO2016196400A1 (en) * | 2015-05-29 | 2016-12-08 | Purdue Research Foundation | Bone fracture repair by targeting of agents that promote bone healing |
| CN106039316B (zh) * | 2016-05-03 | 2019-04-02 | 同济大学 | 一种基于多肽构建的成骨细胞靶向载体及其制备与应用 |
| WO2018102616A1 (en) * | 2016-11-30 | 2018-06-07 | Purdue Research Foundation | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
| WO2022093373A1 (en) * | 2020-10-26 | 2022-05-05 | Purdue Research Foundation | Compounds,compositions and methods of use to treat bone fractures |
-
2017
- 2017-11-30 WO PCT/US2017/064081 patent/WO2018102616A1/en not_active Ceased
- 2017-11-30 CA CA3045458A patent/CA3045458A1/en active Pending
- 2017-11-30 JP JP2019529240A patent/JP7649624B2/ja active Active
- 2017-11-30 CN CN201780073942.4A patent/CN110114065A/zh active Pending
- 2017-11-30 IL IL266977A patent/IL266977B2/en unknown
- 2017-11-30 BR BR112019011070-4A patent/BR112019011070A2/pt active Search and Examination
- 2017-11-30 EP EP17875427.1A patent/EP3548012A4/en active Pending
- 2017-11-30 MX MX2019006189A patent/MX2019006189A/es unknown
- 2017-11-30 US US16/464,164 patent/US20200317745A1/en not_active Abandoned
- 2017-11-30 AU AU2017367699A patent/AU2017367699B2/en active Active
-
2020
- 2020-03-31 US US16/836,366 patent/US10960054B2/en active Active
-
2021
- 2021-02-24 US US17/184,400 patent/US20210283227A1/en active Pending
-
2022
- 2022-12-02 JP JP2022193738A patent/JP2023029957A/ja active Pending
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