JP2020174626A5 - - Google Patents

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JP2020174626A5
JP2020174626A5 JP2019081276A JP2019081276A JP2020174626A5 JP 2020174626 A5 JP2020174626 A5 JP 2020174626A5 JP 2019081276 A JP2019081276 A JP 2019081276A JP 2019081276 A JP2019081276 A JP 2019081276A JP 2020174626 A5 JP2020174626 A5 JP 2020174626A5
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genotype
migraine
data
suffering
humans
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JP2019081276A
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Japanese (ja)
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JP2020174626A (en
JP7107882B2 (en
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偏頭痛に罹患したヒトの遺伝子型データと、偏頭痛に罹患していないヒトの遺伝子型データと、を学習データとして用いて機械学習したモデルを用いて、偏頭痛と正の相関があるrs5945326、rs6651806、rs8067378、rs12688220、rs1934179、及びrs5955543と、偏頭痛と負の相関があるrs4452860、rs671、rs7075195、及びrs258322を少なくとも含む一塩基多型セットの遺伝子型情報であって、 Using a machine-learned model using genotype data of humans suffering from migraine and genotype data of humans not suffering from migraine as training data, there is a positive correlation with migraine rs5945326, Genotype information for a single nucleotide polymorphism set containing at least rs6651806, rs8067378, rs12688220, rs1934179, and rs5955543 and rs4452860, rs671, rs7075195, and rs258322 that are negatively correlated with migraine.
rs5945326の遺伝子型がAG、rs6651806の遺伝子型がAC、rs8067378の遺伝子型がAA、rs12688220の遺伝子型がTC、rs1934179の遺伝子型がTC、rs5955543の遺伝子型がAG、rs4452860の遺伝子型がGG、rs671の遺伝子型がGG、rs7075195の遺伝子型がAA、及びrs258322の遺伝子型がTTであるか否かに関する遺伝子型情報に基づいて、偏頭痛のリスクを判定する、方法。 rs5945326 genotype AG, rs6651806 genotype AC, rs8067378 genotype AA, rs12688220 genotype TC, rs1934179 genotype TC, rs5955543 genotype AG, rs4452860 genotype GG, rs671 A method for determining the risk of migraine based on genotype information regarding whether or not genotype is GG, genotype rs7075195 is AA, and genotype rs258322 is TT.
リスクの判定を受ける対象者の体液サンプル、細胞サンプル又は体毛を用いる、請求項1に記載の方法。The method according to claim 1, wherein a body fluid sample, a cell sample, or hair of a subject who receives a risk determination is used.
JP2019081276A 2019-04-22 2019-04-22 How to Determine Migraine Risk Active JP7107882B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019081276A JP7107882B2 (en) 2019-04-22 2019-04-22 How to Determine Migraine Risk

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Application Number Priority Date Filing Date Title
JP2019081276A JP7107882B2 (en) 2019-04-22 2019-04-22 How to Determine Migraine Risk

Publications (3)

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JP2020174626A JP2020174626A (en) 2020-10-29
JP2020174626A5 true JP2020174626A5 (en) 2022-03-15
JP7107882B2 JP7107882B2 (en) 2022-07-27

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JP2019081276A Active JP7107882B2 (en) 2019-04-22 2019-04-22 How to Determine Migraine Risk

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Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924717D0 (en) * 1999-10-19 1999-12-22 Glaxo Group Ltd Diagnostic
JP2004173505A (en) * 2002-11-22 2004-06-24 Mitsuo Itakura Method for identifying disease-susceptible gene and program and system used therefor
US20080108078A1 (en) * 2006-11-07 2008-05-08 Stephanie Chissoe Genes associated with migraine
WO2008121296A1 (en) * 2007-03-29 2008-10-09 Childrens Hospital Los Angeles Diagnostic methods and kits for functional disorders
AU2008358013A1 (en) * 2008-06-18 2009-12-23 Griffith University Dopamine-beta-hydroxylase genetic polymorphism and migraine
US20130190207A1 (en) * 2010-09-03 2013-07-25 Griffith University Prioritised genetic polymorphisms and migraine susceptibility
KR101325736B1 (en) * 2010-10-27 2013-11-08 삼성에스디에스 주식회사 Apparatus and method for extracting bio markers
AU2012350365B2 (en) * 2011-12-15 2018-08-09 Queensland University Of Technology Genetic polymorphism and responsiveness to vitamin therapy of migraine

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