JP2020178553A5 - - Google Patents

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JP2020178553A5
JP2020178553A5 JP2019081801A JP2019081801A JP2020178553A5 JP 2020178553 A5 JP2020178553 A5 JP 2020178553A5 JP 2019081801 A JP2019081801 A JP 2019081801A JP 2019081801 A JP2019081801 A JP 2019081801A JP 2020178553 A5 JP2020178553 A5 JP 2020178553A5
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genotype
preeclampsia
data
humans
negatively correlated
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JP2019081801A
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JP2020178553A (en
JP7097853B2 (en
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妊娠高血圧症候群に罹患したヒトの遺伝子型データと、妊娠高血圧症候群に罹患していないヒトの遺伝子型データと、を学習データとして用いて機械学習したモデルを用いて、妊娠高血圧症候群と正の相関があるrs5955543、及びrs724577と、妊娠高血圧症候群と負の相関があるrs9895661、及びrs9277535と、妊娠高血圧症候群と正の相関又は負の相関があるrs12688220、rs1934179、及びrs5945326を少なくとも含む一塩基多型セットの遺伝子型情報であって、 Using a machine-learned model using genotype data of humans with preeclampsia and genotype data of humans without preeclampsia as training data, there is a positive correlation with preeclampsia. A one-base genotype set containing at least rs12688220, rs1934179, and rs5945326 with rs5955543 and rs724577 and rs9895661 and rs9277535 that are negatively correlated with preeclampsia and rs12688220, rs1934179, and rs5945326 that are positively or negatively correlated with preeclampsia. Genotype information,
rs5955543の遺伝子型がAG、rs724577の遺伝子型がCC、rs12688220の遺伝子型がTC、rs1934179の遺伝子型がTC、rs5945326の遺伝子型がAG、rs5945326の遺伝子型がAA、rs1934179の遺伝子型がCC、rs9895661の遺伝子型がTC、rs9277535の遺伝子型がAG、及びrs12688220の遺伝子型がCCであるか否かに関する遺伝子型情報に基づいて、妊娠高血圧症候群のリスクを判定する、方法。 rs5955543 genotype AG, rs724577 genotype CC, rs12688220 genotype TC, rs1934179 genotype TC, rs5945326 genotype AG, rs5945326 genotype AA, rs1934179 genotype CC, rs9895661 A method for determining the risk of pregnancy hypertension syndrome based on genotype information regarding whether or not the genotype of rs9277535 is TC, the genotype of rs9277535 is AG, and the genotype of rs12688220 is CC.
リスクの判定を受ける対象者の体液サンプル、細胞サンプル又は体毛を用いる、請求項1に記載の方法。The method according to claim 1, wherein a body fluid sample, a cell sample, or hair of a subject who receives a risk determination is used.
JP2019081801A 2019-04-23 2019-04-23 How to Determine the Risk of Preeclampsia Active JP7097853B2 (en)

Priority Applications (1)

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JP2019081801A JP7097853B2 (en) 2019-04-23 2019-04-23 How to Determine the Risk of Preeclampsia

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JP2019081801A JP7097853B2 (en) 2019-04-23 2019-04-23 How to Determine the Risk of Preeclampsia

Publications (3)

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JP2020178553A JP2020178553A (en) 2020-11-05
JP2020178553A5 true JP2020178553A5 (en) 2022-03-15
JP7097853B2 JP7097853B2 (en) 2022-07-08

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JP2019081801A Active JP7097853B2 (en) 2019-04-23 2019-04-23 How to Determine the Risk of Preeclampsia

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Families Citing this family (1)

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AU2021372103A1 (en) 2020-10-26 2023-06-08 Nippon Steel Corporation Wound core

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004173505A (en) 2002-11-22 2004-06-24 Mitsuo Itakura Method for identifying disease-susceptible gene and program and system used therefor
KR101325736B1 (en) 2010-10-27 2013-11-08 삼성에스디에스 주식회사 Apparatus and method for extracting bio markers
US20180114600A1 (en) 2015-03-23 2018-04-26 Adelaide Research & Innovation Pty Ltd Methods and systems for determining risk of a pregnancy complication occurring
JP7141038B2 (en) 2018-08-31 2022-09-22 株式会社Nttドコモ Onset prediction device and onset prediction system

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