JP2019536570A5 - - Google Patents
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- Publication number
- JP2019536570A5 JP2019536570A5 JP2019529958A JP2019529958A JP2019536570A5 JP 2019536570 A5 JP2019536570 A5 JP 2019536570A5 JP 2019529958 A JP2019529958 A JP 2019529958A JP 2019529958 A JP2019529958 A JP 2019529958A JP 2019536570 A5 JP2019536570 A5 JP 2019536570A5
- Authority
- JP
- Japan
- Prior art keywords
- adsorbent
- dialysate
- sodium
- particles
- exchange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000003463 adsorbent Substances 0.000 claims 54
- 239000002245 particle Substances 0.000 claims 24
- 229910001415 sodium ion Inorganic materials 0.000 claims 19
- 150000001768 cations Chemical class 0.000 claims 17
- 239000003978 infusion fluid Substances 0.000 claims 15
- 238000000502 dialysis Methods 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 9
- 238000005341 cation exchange Methods 0.000 claims 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 8
- 230000001172 regenerating effect Effects 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 239000011734 sodium Substances 0.000 claims 8
- 229910052708 sodium Inorganic materials 0.000 claims 8
- 238000005342 ion exchange Methods 0.000 claims 6
- -1 ammonium ions Chemical class 0.000 claims 5
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 4
- 238000005349 anion exchange Methods 0.000 claims 4
- 239000004202 carbamide Substances 0.000 claims 4
- 150000002500 ions Chemical class 0.000 claims 4
- 239000002207 metabolite Substances 0.000 claims 4
- 239000000243 solution Substances 0.000 claims 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 229910052751 metal Inorganic materials 0.000 claims 3
- 239000002184 metal Substances 0.000 claims 3
- 229910052726 zirconium Inorganic materials 0.000 claims 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 2
- 239000011575 calcium Substances 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 229910052735 hafnium Inorganic materials 0.000 claims 2
- VBJZVLUMGGDVMO-UHFFFAOYSA-N hafnium atom Chemical compound [Hf] VBJZVLUMGGDVMO-UHFFFAOYSA-N 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 239000011777 magnesium Substances 0.000 claims 2
- 229910052749 magnesium Inorganic materials 0.000 claims 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229910052719 titanium Inorganic materials 0.000 claims 2
- 239000010936 titanium Substances 0.000 claims 2
- IVORCBKUUYGUOL-UHFFFAOYSA-N 1-ethynyl-2,4-dimethoxybenzene Chemical compound COC1=CC=C(C#C)C(OC)=C1 IVORCBKUUYGUOL-UHFFFAOYSA-N 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 102000003846 Carbonic anhydrases Human genes 0.000 claims 1
- 108090000209 Carbonic anhydrases Proteins 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 108010046334 Urease Proteins 0.000 claims 1
- 239000006096 absorbing agent Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000001447 alkali salts Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000008240 homogeneous mixture Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229910044991 metal oxide Inorganic materials 0.000 claims 1
- 150000004706 metal oxides Chemical class 0.000 claims 1
- 229910001463 metal phosphate Inorganic materials 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 150000002894 organic compounds Chemical class 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 159000000001 potassium salts Chemical class 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 238000001179 sorption measurement Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022162006A JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201610175P | 2016-12-05 | ||
| SG10201610175P | 2016-12-05 | ||
| PCT/SG2017/050599 WO2018106185A2 (en) | 2016-12-05 | 2017-12-05 | Sorbent for a dialysis device and dialysis system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162006A Division JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019536570A JP2019536570A (ja) | 2019-12-19 |
| JP2019536570A5 true JP2019536570A5 (enExample) | 2020-12-17 |
Family
ID=60812116
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529958A Pending JP2019536570A (ja) | 2016-12-05 | 2017-12-05 | 透析デバイスおよび透析システムのための吸着剤 |
| JP2022162006A Active JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162006A Active JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11458235B2 (enExample) |
| EP (1) | EP3548110B1 (enExample) |
| JP (2) | JP2019536570A (enExample) |
| KR (1) | KR102536334B1 (enExample) |
| CN (1) | CN110049793B (enExample) |
| AU (1) | AU2017371552B2 (enExample) |
| CA (1) | CA3044805A1 (enExample) |
| WO (1) | WO2018106185A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018106185A2 (en) | 2016-12-05 | 2018-06-14 | Temasek Polytechnic | Sorbent for a dialysis device and dialysis system |
| US11090421B2 (en) * | 2018-11-28 | 2021-08-17 | Baxter International Inc. | Systems and methods for batch sorbent material reuse |
| US11331597B2 (en) | 2019-08-05 | 2022-05-17 | Fresenius Medical Care Holdings, Inc. | Cation exchange materials for dialysis systems |
| CN115297953B (zh) * | 2019-11-22 | 2024-10-15 | 德国科技术基金会 | 用于改进尿素捕获的包含吸附剂颗粒的多孔膜 |
| US12290621B2 (en) | 2020-04-13 | 2025-05-06 | Temasek Polytechnic | Dialysate regenerator comprising reversible retainer |
| CN111529785B (zh) * | 2020-05-20 | 2021-06-11 | 浙江大学 | 一种可调节血液流量的透析机 |
| CN111939354B (zh) * | 2020-07-30 | 2022-05-10 | 中国科学院生态环境研究中心 | 一种用于透析液再生的酸碱调节液和透析液再生方法 |
| EP4255521A1 (en) * | 2020-12-02 | 2023-10-11 | W. L. Gore & Associates, Inc. | Dialysate filter |
| WO2022251494A1 (en) * | 2021-05-28 | 2022-12-01 | Diality Inc. | Sorbent regeneration cartridge for dialysis |
| CN113384403A (zh) * | 2021-06-18 | 2021-09-14 | 贵州卡布国际生物科技有限公司 | 一种尿液吸附材料及包含该尿液吸附材料的吸收芯体 |
| EP4440747A2 (en) * | 2021-11-30 | 2024-10-09 | Awak Technologies Pte Ltd | Sorbent for dialysis and sorbent system for regenerative dialysis |
| CN115193489B (zh) * | 2022-09-13 | 2022-12-09 | 兰州大学 | 一种颗粒增强离子交换树脂及其制备方法和应用 |
| CN120022442B (zh) * | 2025-01-20 | 2025-11-18 | 华东理工大学 | 一种血液透析机透析液钾离子实时自动调控系统 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3850835A (en) | 1971-11-08 | 1974-11-26 | Cci Life Systems Inc | Method of making granular zirconium hydrous oxide ion exchangers, such as zirconium phosphate and hydrous zirconium oxide, particularly for column use |
| US4256718A (en) | 1978-03-20 | 1981-03-17 | Organon Teknika Corporation | Sodium zirconium carbonate compound and the method of its preparation |
| JPS5819265A (ja) * | 1981-07-23 | 1983-02-04 | 財団法人生産開発科学研究所 | 血液透析方式膜型人工肺装置 |
| US6627164B1 (en) | 2000-11-28 | 2003-09-30 | Renal Solutions, Inc. | Sodium zirconium carbonate and zirconium basic carbonate and methods of making the same |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| US7776210B2 (en) | 2004-06-09 | 2010-08-17 | Renal Solutions, Inc. | Dialysis system |
| US8715221B2 (en) * | 2006-03-08 | 2014-05-06 | Fresenius Medical Care Holdings, Inc. | Wearable kidney |
| CA2704011C (en) | 2007-11-16 | 2016-07-05 | Fresenius Medical Care Holdings, Inc. | Dialysis systems and methods |
| US8220643B2 (en) | 2008-06-06 | 2012-07-17 | Fresenius Medical Care Holdings, Inc. | Urea sorbent |
| ES2821448T3 (es) | 2008-06-23 | 2021-04-26 | Temasek Polytechnic | Sorbente para un dispositivo de diálisis |
| US8409444B2 (en) | 2008-09-30 | 2013-04-02 | Fresenius Medical Care Holdings, Inc. | Acid zirconium phosphate and alkaline hydrous zirconium oxide materials for sorbent dialysis |
| US8777892B2 (en) * | 2008-11-03 | 2014-07-15 | Fresenius Medical Care Holdings, Inc. | Portable peritoneal dialysis system |
| US8174386B2 (en) | 2008-11-28 | 2012-05-08 | Electronics And Telecommunications Research Institute | RFID reader controlling device, interlocking method for RFID reader, and RFID reader controlling method |
| GB201002824D0 (en) | 2010-02-19 | 2010-04-07 | Temasek Polytechnic | A method of preparing a substrate for immobilization of functional substances thereon and the substrate obtained therefrom |
| GB201019228D0 (en) | 2010-11-15 | 2010-12-29 | Corp | Dialysis device and method of dialysis |
| US10695481B2 (en) | 2011-08-02 | 2020-06-30 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
| US10857277B2 (en) | 2011-08-16 | 2020-12-08 | Medtronic, Inc. | Modular hemodialysis system |
| US10018607B2 (en) | 2011-11-08 | 2018-07-10 | Temasek Polytechnic | Sensing system for detecting a substance in a dialysate |
| AU2012336423B2 (en) * | 2011-11-08 | 2017-08-03 | Temasek Polytechnic | Sensing system for detecting a substance in a dialysate |
| CA2862208A1 (en) | 2012-01-19 | 2013-07-25 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| US9144640B2 (en) | 2013-02-02 | 2015-09-29 | Medtronic, Inc. | Sorbent cartridge configurations for improved dialysate regeneration |
| US9707329B2 (en) * | 2013-10-23 | 2017-07-18 | Fresenius Medical Care Holdings, Inc. | Process for regeneration of spent zirconium phosphate for reuse in sorbent treatments |
| US9943780B2 (en) * | 2013-11-26 | 2018-04-17 | Medtronic, Inc. | Module for in-line recharging of sorbent materials with optional bypass |
| EP3107599B1 (en) * | 2014-02-19 | 2021-09-01 | Medtronic, Inc. | Module for in-line recharging of sorbent materials with optional bypass |
| RU2635143C1 (ru) | 2014-03-17 | 2017-11-09 | Фрезениус Медикал Кеа Холдингс, Инк. | Картриджи, которые можно использовать в очищающих растворах для диализа |
| US10357757B2 (en) * | 2014-06-24 | 2019-07-23 | Medtronic, Inc. | Stacked sorbent assembly |
| WO2018106185A2 (en) | 2016-12-05 | 2018-06-14 | Temasek Polytechnic | Sorbent for a dialysis device and dialysis system |
-
2017
- 2017-12-05 WO PCT/SG2017/050599 patent/WO2018106185A2/en not_active Ceased
- 2017-12-05 CA CA3044805A patent/CA3044805A1/en active Pending
- 2017-12-05 EP EP17821739.4A patent/EP3548110B1/en active Active
- 2017-12-05 JP JP2019529958A patent/JP2019536570A/ja active Pending
- 2017-12-05 US US16/466,138 patent/US11458235B2/en active Active
- 2017-12-05 CN CN201780075463.6A patent/CN110049793B/zh active Active
- 2017-12-05 AU AU2017371552A patent/AU2017371552B2/en active Active
- 2017-12-05 KR KR1020197017653A patent/KR102536334B1/ko active Active
-
2022
- 2022-08-22 US US17/892,973 patent/US12427511B2/en active Active
- 2022-10-07 JP JP2022162006A patent/JP7564850B2/ja active Active
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