JP2019536570A5 - - Google Patents
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- Publication number
- JP2019536570A5 JP2019536570A5 JP2019529958A JP2019529958A JP2019536570A5 JP 2019536570 A5 JP2019536570 A5 JP 2019536570A5 JP 2019529958 A JP2019529958 A JP 2019529958A JP 2019529958 A JP2019529958 A JP 2019529958A JP 2019536570 A5 JP2019536570 A5 JP 2019536570A5
- Authority
- JP
- Japan
- Prior art keywords
- adsorbent
- dialysate
- sodium
- particles
- exchange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000003463 adsorbent Substances 0.000 claims 54
- 239000002245 particle Substances 0.000 claims 24
- 229910001415 sodium ion Inorganic materials 0.000 claims 19
- 150000001768 cations Chemical class 0.000 claims 17
- 239000003978 infusion fluid Substances 0.000 claims 15
- 238000000502 dialysis Methods 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 9
- 238000005341 cation exchange Methods 0.000 claims 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 8
- 230000001172 regenerating effect Effects 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 239000011734 sodium Substances 0.000 claims 8
- 229910052708 sodium Inorganic materials 0.000 claims 8
- 238000005342 ion exchange Methods 0.000 claims 6
- -1 ammonium ions Chemical class 0.000 claims 5
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 4
- 238000005349 anion exchange Methods 0.000 claims 4
- 239000004202 carbamide Substances 0.000 claims 4
- 150000002500 ions Chemical class 0.000 claims 4
- 239000002207 metabolite Substances 0.000 claims 4
- 239000000243 solution Substances 0.000 claims 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 229910052751 metal Inorganic materials 0.000 claims 3
- 239000002184 metal Substances 0.000 claims 3
- 229910052726 zirconium Inorganic materials 0.000 claims 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 2
- 239000011575 calcium Substances 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 229910052735 hafnium Inorganic materials 0.000 claims 2
- VBJZVLUMGGDVMO-UHFFFAOYSA-N hafnium atom Chemical compound [Hf] VBJZVLUMGGDVMO-UHFFFAOYSA-N 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 239000011777 magnesium Substances 0.000 claims 2
- 229910052749 magnesium Inorganic materials 0.000 claims 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229910052719 titanium Inorganic materials 0.000 claims 2
- 239000010936 titanium Substances 0.000 claims 2
- IVORCBKUUYGUOL-UHFFFAOYSA-N 1-ethynyl-2,4-dimethoxybenzene Chemical compound COC1=CC=C(C#C)C(OC)=C1 IVORCBKUUYGUOL-UHFFFAOYSA-N 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 102000003846 Carbonic anhydrases Human genes 0.000 claims 1
- 108090000209 Carbonic anhydrases Proteins 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 108010046334 Urease Proteins 0.000 claims 1
- 239000006096 absorbing agent Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000001447 alkali salts Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000008240 homogeneous mixture Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229910044991 metal oxide Inorganic materials 0.000 claims 1
- 150000004706 metal oxides Chemical class 0.000 claims 1
- 229910001463 metal phosphate Inorganic materials 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 150000002894 organic compounds Chemical class 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 159000000001 potassium salts Chemical class 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 238000001179 sorption measurement Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022162006A JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201610175P | 2016-12-05 | ||
| SG10201610175P | 2016-12-05 | ||
| PCT/SG2017/050599 WO2018106185A2 (en) | 2016-12-05 | 2017-12-05 | Sorbent for a dialysis device and dialysis system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162006A Division JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019536570A JP2019536570A (ja) | 2019-12-19 |
| JP2019536570A5 true JP2019536570A5 (cg-RX-API-DMAC10.html) | 2020-12-17 |
Family
ID=60812116
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529958A Pending JP2019536570A (ja) | 2016-12-05 | 2017-12-05 | 透析デバイスおよび透析システムのための吸着剤 |
| JP2022162006A Active JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162006A Active JP7564850B2 (ja) | 2016-12-05 | 2022-10-07 | 透析デバイスおよび透析システムのための吸着剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11458235B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3548110B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP2019536570A (cg-RX-API-DMAC10.html) |
| KR (1) | KR102536334B1 (cg-RX-API-DMAC10.html) |
| CN (1) | CN110049793B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2017371552B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3044805A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2018106185A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102536334B1 (ko) | 2016-12-05 | 2023-05-24 | 테마섹 폴리테크닉 | 투석 장치용 흡착제 및 투석 시스템 |
| US11090421B2 (en) * | 2018-11-28 | 2021-08-17 | Baxter International Inc. | Systems and methods for batch sorbent material reuse |
| US11331597B2 (en) | 2019-08-05 | 2022-05-17 | Fresenius Medical Care Holdings, Inc. | Cation exchange materials for dialysis systems |
| WO2021099578A1 (en) * | 2019-11-22 | 2021-05-27 | Stichting Voor De Technische Wetenschappen | Porous membranes comprising sorbent particles for improved urea capture |
| CN115916285B (zh) * | 2020-04-13 | 2025-08-26 | 淡马锡理工学院 | 包含可逆保持器的透析液再生器 |
| CN111529785B (zh) * | 2020-05-20 | 2021-06-11 | 浙江大学 | 一种可调节血液流量的透析机 |
| CN111939354B (zh) * | 2020-07-30 | 2022-05-10 | 中国科学院生态环境研究中心 | 一种用于透析液再生的酸碱调节液和透析液再生方法 |
| US20240001015A1 (en) * | 2020-12-02 | 2024-01-04 | W. L. Gore & Associates, Inc. | Dialysate filter |
| EP4346937A4 (en) * | 2021-05-28 | 2025-03-12 | Diality Inc. | Sorbent regeneration cartridge for dialysis |
| CN113384403A (zh) * | 2021-06-18 | 2021-09-14 | 贵州卡布国际生物科技有限公司 | 一种尿液吸附材料及包含该尿液吸附材料的吸收芯体 |
| JP2024544762A (ja) * | 2021-11-30 | 2024-12-04 | アワック テクノロジーズ プライベート リミテッド | 透析用吸着剤および再生透析の吸着システム |
| CN115193489B (zh) * | 2022-09-13 | 2022-12-09 | 兰州大学 | 一种颗粒增强离子交换树脂及其制备方法和应用 |
| CN120022442B (zh) * | 2025-01-20 | 2025-11-18 | 华东理工大学 | 一种血液透析机透析液钾离子实时自动调控系统 |
Family Cites Families (27)
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| US3850835A (en) | 1971-11-08 | 1974-11-26 | Cci Life Systems Inc | Method of making granular zirconium hydrous oxide ion exchangers, such as zirconium phosphate and hydrous zirconium oxide, particularly for column use |
| US4256718A (en) | 1978-03-20 | 1981-03-17 | Organon Teknika Corporation | Sodium zirconium carbonate compound and the method of its preparation |
| JPS5819265A (ja) * | 1981-07-23 | 1983-02-04 | 財団法人生産開発科学研究所 | 血液透析方式膜型人工肺装置 |
| US6627164B1 (en) | 2000-11-28 | 2003-09-30 | Renal Solutions, Inc. | Sodium zirconium carbonate and zirconium basic carbonate and methods of making the same |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| JP4653170B2 (ja) | 2004-06-09 | 2011-03-16 | リナル・ソリューションズ・インコーポレーテッド | 透析システム |
| US8715221B2 (en) | 2006-03-08 | 2014-05-06 | Fresenius Medical Care Holdings, Inc. | Wearable kidney |
| CA2704011C (en) | 2007-11-16 | 2016-07-05 | Fresenius Medical Care Holdings, Inc. | Dialysis systems and methods |
| US8220643B2 (en) | 2008-06-06 | 2012-07-17 | Fresenius Medical Care Holdings, Inc. | Urea sorbent |
| US9242036B2 (en) | 2008-06-23 | 2016-01-26 | Temasek Polytechnic | Sorbent for a dialysis device |
| US8409444B2 (en) | 2008-09-30 | 2013-04-02 | Fresenius Medical Care Holdings, Inc. | Acid zirconium phosphate and alkaline hydrous zirconium oxide materials for sorbent dialysis |
| WO2010062716A2 (en) * | 2008-11-03 | 2010-06-03 | Fresenius Medical Care Holdings, Inc. | Portable peritoneal dialysis system |
| US8174386B2 (en) * | 2008-11-28 | 2012-05-08 | Electronics And Telecommunications Research Institute | RFID reader controlling device, interlocking method for RFID reader, and RFID reader controlling method |
| GB201002824D0 (en) | 2010-02-19 | 2010-04-07 | Temasek Polytechnic | A method of preparing a substrate for immobilization of functional substances thereon and the substrate obtained therefrom |
| WO2013070172A1 (en) * | 2011-11-08 | 2013-05-16 | Temasek Polytechnic | Sensing system for detecting a substance in a dialysate |
| GB201019228D0 (en) | 2010-11-15 | 2010-12-29 | Corp | Dialysis device and method of dialysis |
| EP3165245B1 (en) | 2011-08-02 | 2019-02-20 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
| EP2744537B1 (en) * | 2011-08-16 | 2018-01-24 | Medtronic, Inc. | Modular hemodialysis system |
| US10018607B2 (en) | 2011-11-08 | 2018-07-10 | Temasek Polytechnic | Sensing system for detecting a substance in a dialysate |
| CA2862208A1 (en) * | 2012-01-19 | 2013-07-25 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| US9144640B2 (en) * | 2013-02-02 | 2015-09-29 | Medtronic, Inc. | Sorbent cartridge configurations for improved dialysate regeneration |
| US9707329B2 (en) * | 2013-10-23 | 2017-07-18 | Fresenius Medical Care Holdings, Inc. | Process for regeneration of spent zirconium phosphate for reuse in sorbent treatments |
| US9943780B2 (en) * | 2013-11-26 | 2018-04-17 | Medtronic, Inc. | Module for in-line recharging of sorbent materials with optional bypass |
| JP6438042B2 (ja) * | 2014-02-19 | 2018-12-12 | メドトロニック，インコーポレイテッド | 任意のバイパスを用いて吸着材料をインラインで再充填するためのモジュール |
| WO2015142624A1 (en) * | 2014-03-17 | 2015-09-24 | Fresenius Medical Care Holdings, Inc. | Cartridges useful in cleaning dialysis solutions |
| EP3160534A4 (en) * | 2014-06-24 | 2018-03-07 | Medtronic Inc. | Stacked sorbent assembly |
| KR102536334B1 (ko) | 2016-12-05 | 2023-05-24 | 테마섹 폴리테크닉 | 투석 장치용 흡착제 및 투석 시스템 |
-
2017
- 2017-12-05 KR KR1020197017653A patent/KR102536334B1/ko active Active
- 2017-12-05 AU AU2017371552A patent/AU2017371552B2/en active Active
- 2017-12-05 US US16/466,138 patent/US11458235B2/en active Active
- 2017-12-05 WO PCT/SG2017/050599 patent/WO2018106185A2/en not_active Ceased
- 2017-12-05 CN CN201780075463.6A patent/CN110049793B/zh active Active
- 2017-12-05 CA CA3044805A patent/CA3044805A1/en active Pending
- 2017-12-05 JP JP2019529958A patent/JP2019536570A/ja active Pending
- 2017-12-05 EP EP17821739.4A patent/EP3548110B1/en active Active
-
2022
- 2022-08-22 US US17/892,973 patent/US12427511B2/en active Active
- 2022-10-07 JP JP2022162006A patent/JP7564850B2/ja active Active
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