JP2019535807A5 - - Google Patents
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- JP2019535807A5 JP2019535807A5 JP2019541679A JP2019541679A JP2019535807A5 JP 2019535807 A5 JP2019535807 A5 JP 2019535807A5 JP 2019541679 A JP2019541679 A JP 2019541679A JP 2019541679 A JP2019541679 A JP 2019541679A JP 2019535807 A5 JP2019535807 A5 JP 2019535807A5
- Authority
- JP
- Japan
- Prior art keywords
- nitrogen
- oxygen
- sulfur
- independently
- heteroatoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022000195A JP7498200B2 (ja) | 2016-10-14 | 2022-01-04 | Ｔｙｋ２阻害剤およびその使用 |
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662408464P | 2016-10-14 | 2016-10-14 | |
| US62/408,464 | 2016-10-14 | ||
| US201662410334P | 2016-10-19 | 2016-10-19 | |
| US201662410327P | 2016-10-19 | 2016-10-19 | |
| US62/410,334 | 2016-10-19 | ||
| US62/410,327 | 2016-10-19 | ||
| US201662413829P | 2016-10-27 | 2016-10-27 | |
| US62/413,829 | 2016-10-27 | ||
| US201662415920P | 2016-11-01 | 2016-11-01 | |
| US62/415,920 | 2016-11-01 | ||
| US201762468807P | 2017-03-08 | 2017-03-08 | |
| US201762468767P | 2017-03-08 | 2017-03-08 | |
| US201762468749P | 2017-03-08 | 2017-03-08 | |
| US62/468,807 | 2017-03-08 | ||
| US62/468,749 | 2017-03-08 | ||
| US62/468,767 | 2017-03-08 | ||
| US201762546278P | 2017-08-16 | 2017-08-16 | |
| US62/546,278 | 2017-08-16 | ||
| PCT/US2017/056555 WO2018071794A1 (en) | 2016-10-14 | 2017-10-13 | Tyk2 inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022000195A Division JP7498200B2 (ja) | 2016-10-14 | 2022-01-04 | Ｔｙｋ２阻害剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019535807A JP2019535807A (ja) | 2019-12-12 |
| JP2019535807A5 true JP2019535807A5 (enExample) | 2020-11-19 |
| JP7082130B2 JP7082130B2 (ja) | 2022-06-07 |
Family
ID=61906011
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541679A Active JP7082130B2 (ja) | 2016-10-14 | 2017-10-13 | Ｔｙｋ２阻害剤およびその使用 |
| JP2022000195A Active JP7498200B2 (ja) | 2016-10-14 | 2022-01-04 | Ｔｙｋ２阻害剤およびその使用 |
| JP2023091142A Withdrawn JP2023106606A (ja) | 2016-10-14 | 2023-06-01 | Ｔｙｋ２阻害剤およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022000195A Active JP7498200B2 (ja) | 2016-10-14 | 2022-01-04 | Ｔｙｋ２阻害剤およびその使用 |
| JP2023091142A Withdrawn JP2023106606A (ja) | 2016-10-14 | 2023-06-01 | Ｔｙｋ２阻害剤およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10323036B2 (enExample) |
| EP (2) | EP3526222B1 (enExample) |
| JP (3) | JP7082130B2 (enExample) |
| CN (2) | CN109952303B (enExample) |
| AU (3) | AU2017342464B2 (enExample) |
| CA (1) | CA3039202A1 (enExample) |
| ES (1) | ES2930198T3 (enExample) |
| IL (2) | IL315777A (enExample) |
| TW (2) | TWI825663B (enExample) |
| WO (1) | WO2018071794A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3262049B1 (en) | 2015-02-27 | 2022-07-20 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| WO2017040757A1 (en) | 2015-09-02 | 2017-03-09 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| CN109952303B (zh) | 2016-10-14 | 2022-10-21 | 林伯士拉克许米公司 | Tyk2抑制剂及其用途 |
| GB201617871D0 (en) * | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
| WO2018075937A1 (en) | 2016-10-21 | 2018-04-26 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| IL269036B2 (en) | 2017-03-08 | 2023-03-01 | Nimbus Lakshmi Inc | tyk2 inhibitors, uses and methods for their production |
| US11046698B2 (en) | 2017-07-28 | 2021-06-29 | Nimbus Lakshmi, Inc. | TYK2 inhibitors and uses thereof |
| AR117398A1 (es) | 2018-03-12 | 2021-08-04 | Abbvie Inc | Inhibidores de la señalización mediada por tirosina cinasa 2 |
| US12448374B2 (en) | 2018-06-07 | 2025-10-21 | Disarm Therapeutics, Inc. | Inhibitors of SARM1 |
| EP3846793B1 (en) | 2018-09-07 | 2024-01-24 | PIC Therapeutics, Inc. | Eif4e inhibitors and uses thereof |
| US11414431B2 (en) | 2018-10-15 | 2022-08-16 | Nimbus Lakshmi, Inc. | Substituted pyrazolo[1,5-a]pyrimidines as TYK2 inhibitors |
| CN113271938A (zh) * | 2018-11-30 | 2021-08-17 | 林伯士拉克许米公司 | Tyk2抑制剂和其用途 |
| CA3126034A1 (en) * | 2019-01-23 | 2020-07-30 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| AU2020216914A1 (en) * | 2019-01-30 | 2021-09-16 | Bristol-Myers Squibb Company | Amide-disubstituted pyridine or pyridazine compounds |
| KR20220002488A (ko) | 2019-04-30 | 2022-01-06 | 셀진 코포레이션 | 아프레밀라스트 및 tyk2 억제제를 포함하는 조합 요법 |
| CA3153676A1 (en) * | 2019-09-11 | 2021-03-18 | Pfizer Inc. | Treatment of hidradenitis with jak inhibitors |
| US11753403B2 (en) | 2020-03-03 | 2023-09-12 | PIC Therapeutics, Inc. | EIF4E inhibitors and uses thereof |
| WO2021237121A1 (en) * | 2020-05-21 | 2021-11-25 | Gossamer Bio Services, Inc. | Substituted pyridines |
| EP4168398A4 (en) * | 2020-06-22 | 2024-08-14 | BeiGene, Ltd. | TYK-2 INHIBITOR |
| WO2022083560A1 (zh) * | 2020-10-19 | 2022-04-28 | 南京药石科技股份有限公司 | Tyk2选择性抑制剂及其用途 |
| IL302923A (en) | 2020-11-20 | 2023-07-01 | 2692372 Ontario Inc | Benzenesulfonamide derivatives and uses thereof |
| WO2022136914A1 (en) * | 2020-12-23 | 2022-06-30 | Sudo Biosciences Limited | Tyk2 inhibitors and uses thereof |
| MX2023009685A (es) | 2021-02-19 | 2023-10-30 | Sudo Biosciences Ltd | Inhibidores de tyk2 y sus usos. |
| WO2022175747A1 (en) | 2021-02-19 | 2022-08-25 | Sudo Biosciences Limited | Tyk2 inhibitors and uses thereof |
| US20240246944A1 (en) | 2021-03-16 | 2024-07-25 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Amino heteroaryl compounds and compositions |
| US20240382477A1 (en) * | 2021-05-04 | 2024-11-21 | Shanghai Zheye Biotechnology Co. Ltd. | Nitrogen-containing heterocyclic pyridine compound |
| CN115466289A (zh) * | 2021-06-11 | 2022-12-13 | 爱科诺生物医药(香港)有限公司 | 具有tyk2抑制活性的化合物，包含其的药物组合物，及其应用 |
| CA3229560A1 (en) | 2021-08-25 | 2023-03-02 | Christopher L. Vandeusen | Eif4e inhibitors and uses thereof |
| JP2024532276A (ja) | 2021-08-25 | 2024-09-05 | ピク セラピューティクス， インコーポレイテッド | ｅＩＦ４Ｅ阻害剤及びその使用 |
| KR20240070634A (ko) | 2021-09-30 | 2024-05-21 | 브리스톨-마이어스 스큅 컴퍼니 | Tyk2 억제제에 대한 반응성을 결정하는 방법 |
| US20250051338A1 (en) | 2021-10-25 | 2025-02-13 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
| JP2024544245A (ja) * | 2021-12-23 | 2024-11-28 | ベイジーン スウィッツァーランド ゲーエムベーハー | Ｔｙｋ２阻害剤の固体形態、調製方法、及びその使用 |
| JP2025516586A (ja) * | 2022-05-10 | 2025-05-30 | バイオジェン・エムエイ・インコーポレイテッド | Ｔｙｋ２阻害剤 |
| WO2023248010A2 (en) | 2022-06-23 | 2023-12-28 | Synovo Gmbh | Targeted modulators of jak3 for treatment of inflammatory and autoimmune diseases |
| US20240124450A1 (en) | 2022-09-21 | 2024-04-18 | Pfizer Inc. | Novel SIK Inhibitors |
| CN115819429A (zh) * | 2022-12-13 | 2023-03-21 | 成都睿智化学研究有限公司 | 一种5-氯-2,3-二氢呋喃[2,3-c]吡啶的合成方法 |
| WO2024193689A1 (zh) * | 2023-03-23 | 2024-09-26 | 广东东阳光药业股份有限公司 | 吡啶并吡咯衍生物及其在药物中的用途 |
| WO2024211708A1 (en) * | 2023-04-06 | 2024-10-10 | Myrobalan Therapeutics, Inc. | Tyk2 inhibitors for treatment of glaucoma |
| WO2024217523A1 (en) * | 2023-04-20 | 2024-10-24 | Myrobalan Therapeutics Nanjing Co. Ltd | Selective tky2 inhibitors and uses thereof |
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| US5516931A (en) | 1982-02-01 | 1996-05-14 | Northeastern University | Release tag compounds producing ketone signal groups |
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| UA72290C2 (uk) | 1999-12-10 | 2005-02-15 | Пфайзер Продактс Інк. | СПОЛУКИ ПІРОЛО[2.3-d]ПІРИМІДИНУ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ (ВАРІАНТИ), СПОСІБ ІНГІБУВАННЯ ПРОТЕЇНКІНАЗ АБО JANUS КІНАЗИ 3 (ВАРІАНТИ) |
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| WO2015073267A1 (en) * | 2013-11-15 | 2015-05-21 | Calitor Sciences, Llc | Substituted heteroaryl compounds and methods of use |
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| US9340540B2 (en) * | 2014-02-28 | 2016-05-17 | Nimbus Lakshmi, Inc. | TYK2 inhibitors and uses thereof |
| NO2721710T3 (enExample) * | 2014-08-21 | 2018-03-31 | ||
| EP3262049B1 (en) * | 2015-02-27 | 2022-07-20 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| TW201718571A (zh) * | 2015-06-24 | 2017-06-01 | 必治妥美雅史谷比公司 | 經雜芳基取代之胺基吡啶化合物 |
| CN109952303B (zh) | 2016-10-14 | 2022-10-21 | 林伯士拉克许米公司 | Tyk2抑制剂及其用途 |
-
2017
- 2017-10-13 CN CN201780069795.3A patent/CN109952303B/zh active Active
- 2017-10-13 IL IL315777A patent/IL315777A/en unknown
- 2017-10-13 US US15/783,250 patent/US10323036B2/en active Active
- 2017-10-13 AU AU2017342464A patent/AU2017342464B2/en active Active
- 2017-10-13 ES ES17860009T patent/ES2930198T3/es active Active
- 2017-10-13 WO PCT/US2017/056555 patent/WO2018071794A1/en not_active Ceased
- 2017-10-13 EP EP17860009.4A patent/EP3526222B1/en active Active
- 2017-10-13 EP EP21157963.6A patent/EP3848370B1/en active Active
- 2017-10-13 CA CA3039202A patent/CA3039202A1/en active Pending
- 2017-10-13 IL IL265922A patent/IL265922B2/en unknown
- 2017-10-13 JP JP2019541679A patent/JP7082130B2/ja active Active
- 2017-10-13 TW TW111113673A patent/TWI825663B/zh active
- 2017-10-13 CN CN202211114285.2A patent/CN115448916A/zh active Pending
- 2017-10-13 TW TW106135165A patent/TWI763722B/zh active
-
2019
- 2019-04-30 US US16/399,296 patent/US10793574B2/en active Active
-
2020
- 2020-05-04 US US16/865,924 patent/US11220508B2/en active Active
-
2021
- 2021-09-03 AU AU2021225251A patent/AU2021225251A1/en not_active Abandoned
- 2021-09-17 US US17/448,013 patent/US20220073527A1/en not_active Abandoned
-
2022
- 2022-01-04 JP JP2022000195A patent/JP7498200B2/ja active Active
-
2023
- 2023-06-01 JP JP2023091142A patent/JP2023106606A/ja not_active Withdrawn
- 2023-09-26 AU AU2023237060A patent/AU2023237060B2/en active Active
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