JP2019535788A5 - - Google Patents
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- Publication number
- JP2019535788A5 JP2019535788A5 JP2019528512A JP2019528512A JP2019535788A5 JP 2019535788 A5 JP2019535788 A5 JP 2019535788A5 JP 2019528512 A JP2019528512 A JP 2019528512A JP 2019528512 A JP2019528512 A JP 2019528512A JP 2019535788 A5 JP2019535788 A5 JP 2019535788A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- pharmaceutically acceptable
- halo
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662426631P | 2016-11-28 | 2016-11-28 | |
| US62/426,631 | 2016-11-28 | ||
| PCT/US2017/063231 WO2018098412A1 (en) | 2016-11-28 | 2017-11-27 | Gsk-3 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019535788A JP2019535788A (ja) | 2019-12-12 |
| JP2019535788A5 true JP2019535788A5 (https=) | 2022-03-01 |
| JP7114591B2 JP7114591B2 (ja) | 2022-08-08 |
Family
ID=60655130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019528512A Active JP7114591B2 (ja) | 2016-11-28 | 2017-11-27 | Ｇｓｋ－３阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10752609B2 (https=) |
| EP (1) | EP3544613B1 (https=) |
| JP (1) | JP7114591B2 (https=) |
| KR (1) | KR102575990B1 (https=) |
| CN (1) | CN110545817B (https=) |
| ES (1) | ES2878078T3 (https=) |
| MA (1) | MA46889A (https=) |
| WO (1) | WO2018098412A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102455408B1 (ko) * | 2016-11-28 | 2022-10-14 | 브리스톨-마이어스 스큅 컴퍼니 | Gsk-3 억제제로서의 피리미딘 카르복스아미드 |
| JP2022513967A (ja) * | 2018-12-20 | 2022-02-09 | アムジエン・インコーポレーテツド | Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド |
| AU2019401495B2 (en) | 2018-12-20 | 2025-06-26 | Amgen Inc. | Heteroaryl amides useful as KIF18A inhibitors |
| JP7686559B2 (ja) | 2018-12-20 | 2025-06-02 | アムジエン・インコーポレーテツド | Ｋｉｆ１８ａ阻害剤 |
| EP4007638A1 (en) | 2019-08-02 | 2022-06-08 | Amgen Inc. | Pyridine derivatives as kif18a inhibitors |
| EP4007753B1 (en) | 2019-08-02 | 2025-09-24 | Amgen Inc. | Kif18a inhibitors |
| CN116178281B (zh) * | 2023-04-27 | 2023-07-21 | 中国药科大学 | 一种双功能免疫抑制剂及其制备方法和应用 |
| EP4709712A1 (en) * | 2023-05-10 | 2026-03-18 | Blueprint Medicines Corporation | Gsk3a inhibitors and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0102438D0 (sv) * | 2001-07-05 | 2001-07-05 | Astrazeneca Ab | New compounds |
| MY150032A (en) * | 2007-07-19 | 2013-11-29 | Merck Sharp & Dohme | Heterocyclic amide compounds as protein kinase inhibitors |
| WO2012024179A1 (en) * | 2010-08-18 | 2012-02-23 | Merck Sharp & Dohme Corp. | Substituted amide derivatives as dgat-1 inhibitors |
| AU2014347027A1 (en) * | 2013-11-06 | 2016-06-23 | Bristol-Myers Squibb Company | GSK -3 inhibitors |
| ES2693718T3 (es) * | 2013-11-06 | 2018-12-13 | Bristol-Myers Squibb Company | Derivados de piridina sustituidos útiles como inhibidores de GSK-3 |
| WO2016144797A1 (en) * | 2015-03-06 | 2016-09-15 | Alpharmagen, Llc | Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof |
| KR102455408B1 (ko) * | 2016-11-28 | 2022-10-14 | 브리스톨-마이어스 스큅 컴퍼니 | Gsk-3 억제제로서의 피리미딘 카르복스아미드 |
-
2017
- 2017-11-27 ES ES17812188T patent/ES2878078T3/es active Active
- 2017-11-27 JP JP2019528512A patent/JP7114591B2/ja active Active
- 2017-11-27 US US16/463,467 patent/US10752609B2/en active Active
- 2017-11-27 WO PCT/US2017/063231 patent/WO2018098412A1/en not_active Ceased
- 2017-11-27 MA MA046889A patent/MA46889A/fr unknown
- 2017-11-27 KR KR1020197018285A patent/KR102575990B1/ko active Active
- 2017-11-27 CN CN201780084344.7A patent/CN110545817B/zh active Active
- 2017-11-27 EP EP17812188.5A patent/EP3544613B1/en active Active
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