JP2019535232A5 - - Google Patents
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- Publication number
- JP2019535232A5 JP2019535232A5 JP2019502698A JP2019502698A JP2019535232A5 JP 2019535232 A5 JP2019535232 A5 JP 2019535232A5 JP 2019502698 A JP2019502698 A JP 2019502698A JP 2019502698 A JP2019502698 A JP 2019502698A JP 2019535232 A5 JP2019535232 A5 JP 2019535232A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- antigen
- binding portion
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022035222A JP7486538B2 (ja) | 2016-08-18 | 2022-03-08 | 抗ｐｓｍａ抗体、その使用及びそのコンジュゲート |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1614162.4 | 2016-08-18 | ||
| GBGB1614162.4A GB201614162D0 (en) | 2016-08-18 | 2016-08-18 | Antibodies, uses thereof and conjugates thereof |
| PCT/GB2017/052448 WO2018033749A1 (en) | 2016-08-18 | 2017-08-18 | Anti-psma antibodies, uses thereof and conjugates thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022035222A Division JP7486538B2 (ja) | 2016-08-18 | 2022-03-08 | 抗ｐｓｍａ抗体、その使用及びそのコンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019535232A JP2019535232A (ja) | 2019-12-12 |
| JP2019535232A5 true JP2019535232A5 (https=) | 2020-09-17 |
| JP7039554B2 JP7039554B2 (ja) | 2022-03-22 |
Family
ID=57045541
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502698A Active JP7039554B2 (ja) | 2016-08-18 | 2017-08-18 | 抗ｐｓｍａ抗体、その使用及びそのコンジュゲート |
| JP2022035222A Active JP7486538B2 (ja) | 2016-08-18 | 2022-03-08 | 抗ｐｓｍａ抗体、その使用及びそのコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022035222A Active JP7486538B2 (ja) | 2016-08-18 | 2022-03-08 | 抗ｐｓｍａ抗体、その使用及びそのコンジュゲート |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11059903B2 (https=) |
| EP (2) | EP3500595B1 (https=) |
| JP (2) | JP7039554B2 (https=) |
| CN (1) | CN110049999B (https=) |
| ES (1) | ES2983492T3 (https=) |
| GB (1) | GB201614162D0 (https=) |
| WO (1) | WO2018033749A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018204477A1 (en) | 2017-05-02 | 2018-11-08 | Cornell University | Methods and reagents for tumor targeting with greater efficacy and less toxicity |
| MX2020009272A (es) | 2018-03-06 | 2021-01-08 | Univ Pennsylvania | Receptores de antígeno quimérico del antígeno de membrana específico de próstata y métodos de uso de los mismos. |
| MX2020010104A (es) * | 2018-03-29 | 2020-11-06 | Ambrx Inc | Conjugados de farmaco-anticuerpo anti-antigeno de membrana especifico de prostata (psma) humanizado. |
| EP3994177A4 (en) * | 2019-07-02 | 2023-09-20 | Telix International Pty Ltd | PSMA-BINDING ANTIBODIES WITH REDUCED AFFINITY FOR THE NEONATAL FC RECEPTOR |
| CN114729059A (zh) | 2019-09-11 | 2022-07-08 | 宾夕法尼亚大学董事会 | 包含前列腺干细胞抗原(psca)嵌合抗原受体(cars)的组合物和方法 |
| EP4063387A4 (en) * | 2019-11-22 | 2023-08-02 | Nantong Yichen Biopharma. Co. Ltd. | PSMA ANTIBODIES AND ITS USE |
| CN110922486B (zh) * | 2020-02-18 | 2020-05-22 | 和铂医药(上海)有限责任公司 | 一种分离的结合抗原psma的蛋白及其用途 |
| CN120813607A (zh) * | 2023-02-28 | 2025-10-17 | 卫材R&D管理有限公司 | 抗psma抗体、缀合物和使用方法 |
| IL322949A (en) | 2023-03-03 | 2025-10-01 | Arsenal Biosciences Inc | Systems targeting PSMA and CA9 |
| CN116196428B (zh) * | 2023-04-04 | 2025-04-04 | 上海愿智生物技术有限公司 | 一种药物组合物及其应用 |
| CN116271081A (zh) * | 2023-04-04 | 2023-06-23 | 上海愿智生物技术有限公司 | 一种抗体偶联药物yc1605及其药物组合物和应用 |
| WO2026044149A2 (en) | 2024-08-21 | 2026-02-26 | Eisai R&D Management Co., Ltd. | Synthesis of drug-linker combinations for antibody-drug conjugates |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6107090A (en) | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
| DE69737346T2 (de) | 1996-07-24 | 2007-10-31 | Koninklijke Philips Electronics N.V. | Verbesserungen an optisch lesbaren platten und plattenaufzeichnungsgerät |
| US7514078B2 (en) | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
| JP5355839B2 (ja) | 2001-10-23 | 2013-11-27 | ピーエスエムエー デベロプメント カンパニー， エル．エル．シー． | Ｐｓｍａ抗体およびタンパク質マルチマー |
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| US20040136998A1 (en) | 2002-10-30 | 2004-07-15 | Bander Neil H. | Methods and compositions for treating or preventing insulin-related disorders using binding agents specific for prostate specific membrane antigen |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| GB0316294D0 (en) | 2003-07-11 | 2003-08-13 | Polytherics Ltd | Conjugated biological molecules and their preparation |
| CN101160324B (zh) * | 2005-02-18 | 2013-04-24 | 米德列斯公司 | 缺乏岩藻糖残基的抗前列腺特异性膜抗原(psma)单克隆抗体 |
| JP2008529556A (ja) | 2005-02-18 | 2008-08-07 | メダレックス， インク． | 前立腺特異的膜抗原（ｐｓｍａ）に対するヒトモノクローナル抗体 |
| EP2187971A2 (en) * | 2007-08-01 | 2010-05-26 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | A fold-back diabody diphtheria toxin immunotoxin and methods of use |
| CN101820920B (zh) | 2007-10-09 | 2014-08-06 | 宝力泰锐克斯有限公司 | 新的缀合蛋白质和肽 |
| CN101891818B (zh) * | 2009-01-16 | 2012-07-25 | 中国人民解放军第四军医大学 | 抗人前列腺特异性膜抗原胞外区单链抗体及其应用 |
| EP2403538B1 (en) | 2009-03-04 | 2017-10-04 | Polytherics Limited | Conjugated proteins and peptides |
| EP2861261A2 (en) * | 2012-06-19 | 2015-04-22 | Polytherics Limited | Process for preparation of antibody conjugates and antibody conjugates |
| NO2789793T3 (https=) | 2012-10-24 | 2018-01-27 | ||
| US20150290342A1 (en) | 2012-10-24 | 2015-10-15 | Polytherics Limited | Drug-protein conjugates |
| IL311390A (en) * | 2013-03-15 | 2024-05-01 | Memorial Sloan Kettering Cancer Center | Preparations and methods for immunotherapy |
| JP6908964B2 (ja) * | 2013-10-18 | 2021-07-28 | ピーエスエムエー ディベロップメント カンパニー，エルエルシー | Ｐｓｍａリガンドコンジュゲートによる併用療法 |
| US20150110814A1 (en) * | 2013-10-18 | 2015-04-23 | Psma Development Company, Llc | Combination therapies with psma ligand conjugates |
| SG11201609372UA (en) * | 2014-05-22 | 2016-12-29 | Synthon Biopharmaceuticals Bv | Site-specific conjugation of linker drugs to antibodies and resulting adcs |
| EP3218009B1 (en) | 2014-10-14 | 2021-04-07 | Polytherics Limited | Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of peg |
| BR112017005760A2 (pt) | 2014-10-24 | 2017-12-12 | Polytherics Ltd | conjugados e reagentes de conjugação |
| MX2020009272A (es) * | 2018-03-06 | 2021-01-08 | Univ Pennsylvania | Receptores de antígeno quimérico del antígeno de membrana específico de próstata y métodos de uso de los mismos. |
-
2016
- 2016-08-18 GB GBGB1614162.4A patent/GB201614162D0/en not_active Ceased
-
2017
- 2017-08-18 WO PCT/GB2017/052448 patent/WO2018033749A1/en not_active Ceased
- 2017-08-18 EP EP17757849.9A patent/EP3500595B1/en active Active
- 2017-08-18 CN CN201780044227.8A patent/CN110049999B/zh active Active
- 2017-08-18 ES ES17757849T patent/ES2983492T3/es active Active
- 2017-08-18 US US16/303,600 patent/US11059903B2/en active Active
- 2017-08-18 EP EP24173428.4A patent/EP4403226A3/en active Pending
- 2017-08-18 JP JP2019502698A patent/JP7039554B2/ja active Active
-
2022
- 2022-03-08 JP JP2022035222A patent/JP7486538B2/ja active Active
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