JP2019532031A5 - - Google Patents
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- Publication number
- JP2019532031A5 JP2019532031A5 JP2019511658A JP2019511658A JP2019532031A5 JP 2019532031 A5 JP2019532031 A5 JP 2019532031A5 JP 2019511658 A JP2019511658 A JP 2019511658A JP 2019511658 A JP2019511658 A JP 2019511658A JP 2019532031 A5 JP2019532031 A5 JP 2019532031A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkylenyl
- hydrogen
- heterocyclyl
- carbocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VZKYFJQZMLDYED-UHFFFAOYSA-N CC(C)NC(CN1CCCC1)=O Chemical compound CC(C)NC(CN1CCCC1)=O VZKYFJQZMLDYED-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381383P | 2016-08-30 | 2016-08-30 | |
| US62/381,383 | 2016-08-30 | ||
| US201662437533P | 2016-12-21 | 2016-12-21 | |
| US62/437,533 | 2016-12-21 | ||
| PCT/US2017/049462 WO2018045084A1 (en) | 2016-08-30 | 2017-08-30 | Tetracycline compounds and methods of treatment |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2019532031A JP2019532031A (ja) | 2019-11-07 |
| JP2019532031A5 true JP2019532031A5 (enExample) | 2020-10-08 |
| JP7184756B2 JP7184756B2 (ja) | 2022-12-06 |
| JP7184756B6 JP7184756B6 (ja) | 2022-12-20 |
Family
ID=59982459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511658A Expired - Fee Related JP7184756B6 (ja) | 2016-08-30 | 2017-08-30 | テトラサイクリン化合物および処置方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20230031954A1 (enExample) |
| EP (1) | EP3506908A1 (enExample) |
| JP (1) | JP7184756B6 (enExample) |
| KR (1) | KR102558540B1 (enExample) |
| CN (1) | CN110167560B (enExample) |
| AU (1) | AU2017319513B2 (enExample) |
| CA (1) | CA3034891A1 (enExample) |
| CL (1) | CL2019000542A1 (enExample) |
| CO (1) | CO2019002975A2 (enExample) |
| IL (1) | IL264878B (enExample) |
| MA (1) | MA46102A (enExample) |
| MX (1) | MX2019002453A (enExample) |
| MY (1) | MY204572A (enExample) |
| SG (2) | SG10202101986UA (enExample) |
| WO (1) | WO2018045084A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201902057T4 (tr) | 2012-08-31 | 2019-03-21 | Tetraphase Pharmaceuticals Inc | Tetrasiklin bileşikleri. |
| US20170107216A1 (en) | 2015-10-19 | 2017-04-20 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| MD3377488T2 (ro) | 2015-11-19 | 2023-02-28 | Incyte Corp | Compuși heterociclici ca imunomodulatori |
| ES2916874T3 (es) | 2015-12-17 | 2022-07-06 | Incyte Corp | Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1 |
| CA3009474A1 (en) | 2015-12-22 | 2017-06-29 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| ES2906460T3 (es) | 2016-05-06 | 2022-04-18 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
| EP3464279B1 (en) | 2016-05-26 | 2021-11-24 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| SG11201811414TA (en) | 2016-06-20 | 2019-01-30 | Incyte Corp | Heterocyclic compounds as immunomodulators |
| MA45669A (fr) | 2016-07-14 | 2019-05-22 | Incyte Corp | Composés hétérocycliques utilisés comme immunomodulateurs |
| US20180057486A1 (en) | 2016-08-29 | 2018-03-01 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| MA46567A (fr) | 2016-10-19 | 2019-08-28 | Tetraphase Pharmaceuticals Inc | Formes cristallines de l'éravacycline |
| WO2018119221A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Pyridine derivatives as immunomodulators |
| WO2018119286A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Bicyclic heteroaromatic compounds as immunomodulators |
| US10308644B2 (en) | 2016-12-22 | 2019-06-04 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| WO2018119236A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Triazolo[1,5-a]pyridine derivatives as immunomodulators |
| SMT202300065T1 (it) | 2018-03-30 | 2023-05-12 | Incyte Corp | Composti eterociclici come immunomodulatori |
| CN112752756B (zh) | 2018-05-11 | 2024-06-25 | 因赛特公司 | 作为PD-L1免疫调节剂的四氢-咪唑并[4,5-c]吡啶衍生物 |
| WO2021022258A1 (en) * | 2019-08-01 | 2021-02-04 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds for the treatment of hematological cancers |
| TW202115059A (zh) | 2019-08-09 | 2021-04-16 | 美商英塞特公司 | Ｐｄ—１／ｐｄ—ｌ１抑制劑之鹽 |
| JP7559059B2 (ja) | 2019-09-30 | 2024-10-01 | インサイト・コーポレイション | 免疫調節剤としてのピリド［３，２－ｄ］ピリミジン化合物 |
| EP4058461A1 (en) | 2019-11-11 | 2022-09-21 | Incyte Corporation | Salts and crystalline forms of a pd-1/pd-l1 inhibitor |
| BR112022025037A2 (pt) | 2020-06-10 | 2023-02-14 | Aligos Therapeutics Inc | Compostos antivirais para tratar infecções por coronavírus, picornavírus e norovírus |
| IL302590A (en) | 2020-11-06 | 2023-07-01 | Incyte Corp | Process for preparing PD-1/PD-L1 inhibitor and salts and crystalline forms thereof |
| US11780836B2 (en) | 2020-11-06 | 2023-10-10 | Incyte Corporation | Process of preparing a PD-1/PD-L1 inhibitor |
| US11760756B2 (en) | 2020-11-06 | 2023-09-19 | Incyte Corporation | Crystalline form of a PD-1/PD-L1 inhibitor |
| WO2023283256A1 (en) | 2021-07-09 | 2023-01-12 | Aligos Therapeutics, Inc. | Anti-viral compounds |
| US12065428B2 (en) | 2021-09-17 | 2024-08-20 | Aligos Therapeutics, Inc. | Anti-viral compounds |
| AU2023303408A1 (en) | 2022-07-06 | 2024-12-19 | Aligos Therapeutics, Inc. | Anti-viral compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1077598A (en) * | 1965-05-12 | 1967-08-02 | Pfizer & Co C | Preparation of n-demethyl tetracyclines |
| WO2005082860A1 (en) | 2004-02-27 | 2005-09-09 | National Research Council Of Canada | Tetracyclines and their use as calpain inhibitors |
| US7838524B2 (en) * | 2004-04-30 | 2010-11-23 | Bayer Healthcare Llc | Substituted pyrazolyl urea derivatives useful in the treatment of cancer |
| HUE026562T2 (hu) * | 2008-08-08 | 2016-06-28 | Tetraphase Pharmaceuticals Inc | C7-fluor-helyettesített tetraciklin vegyületek |
| CN102459153A (zh) | 2009-05-08 | 2012-05-16 | 四相制药公司 | 四环素类化合物 |
| US8367654B2 (en) | 2009-05-08 | 2013-02-05 | Tetraphase Pharmaceuticals, Inc. | 8-AZA tetracycline compounds |
| EP2470500B1 (en) * | 2009-08-28 | 2017-10-04 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| US20120329761A1 (en) * | 2010-03-10 | 2012-12-27 | University Health Network | Use of tigecycline for treatment of cancer |
| WO2011123536A1 (en) * | 2010-03-31 | 2011-10-06 | Tetraphase Pharmaceuticals, Inc. | Polycyclic tetracycline compounds |
| WO2011146089A1 (en) | 2010-05-21 | 2011-11-24 | Abbott Laboratories | Modulators of 5-ht receptors and methods of use thereof |
| WO2012021712A1 (en) * | 2010-08-12 | 2012-02-16 | Tetraphase Pharmaceuticals, Inc. | Tetracycline analogs |
| SE536617C2 (sv) | 2012-06-28 | 2014-04-01 | Cargine Engineering Ab | Metod och positioneringssensorsammansättning för fastställning av en inbördes position mellan ett första objekt och ettandra objekt |
| TR201902057T4 (tr) * | 2012-08-31 | 2019-03-21 | Tetraphase Pharmaceuticals Inc | Tetrasiklin bileşikleri. |
-
2017
- 2017-08-30 MA MA046102A patent/MA46102A/fr unknown
- 2017-08-30 IL IL264878A patent/IL264878B/en unknown
- 2017-08-30 AU AU2017319513A patent/AU2017319513B2/en not_active Ceased
- 2017-08-30 US US16/328,559 patent/US20230031954A1/en not_active Abandoned
- 2017-08-30 SG SG10202101986UA patent/SG10202101986UA/en unknown
- 2017-08-30 WO PCT/US2017/049462 patent/WO2018045084A1/en not_active Ceased
- 2017-08-30 EP EP17777422.1A patent/EP3506908A1/en not_active Withdrawn
- 2017-08-30 JP JP2019511658A patent/JP7184756B6/ja not_active Expired - Fee Related
- 2017-08-30 MX MX2019002453A patent/MX2019002453A/es unknown
- 2017-08-30 SG SG11201901390TA patent/SG11201901390TA/en unknown
- 2017-08-30 CA CA3034891A patent/CA3034891A1/en active Pending
- 2017-08-30 MY MYPI2019001102A patent/MY204572A/en unknown
- 2017-08-30 CN CN201780064847.8A patent/CN110167560B/zh not_active Expired - Fee Related
- 2017-08-30 KR KR1020197008575A patent/KR102558540B1/ko active Active
-
2019
- 2019-02-28 CL CL2019000542A patent/CL2019000542A1/es unknown
- 2019-03-27 CO CONC2019/0002975A patent/CO2019002975A2/es unknown
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