JP2019531286A - Ｃｈｓ−１３１による多発性硬化症の治療 - Google Patents

Ｃｈｓ−１３１による多発性硬化症の治療 Download PDF

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JP2019531286A
JP2019531286A JP2019513922A JP2019513922A JP2019531286A JP 2019531286 A JP2019531286 A JP 2019531286A JP 2019513922 A JP2019513922 A JP 2019513922A JP 2019513922 A JP2019513922 A JP 2019513922A JP 2019531286 A JP2019531286 A JP 2019531286A
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effective amount
therapeutically effective
compound
multiple sclerosis
milligrams
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Japanese (ja)
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JP2019531286A5 (enExample
Inventor
バルバラ フィンク
バルバラ フィンク
ロバート ジバディノフ
ロバート ジバディノフ
ホン タン
ホン タン
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インテクリン セラピューティクス インコーポレイテッド
インテクリン セラピューティクス インコーポレイテッド
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Publication of JP2019531286A publication Critical patent/JP2019531286A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019513922A 2016-09-13 2017-09-13 Ｃｈｓ−１３１による多発性硬化症の治療 Pending JP2019531286A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662394046P 2016-09-13 2016-09-13
US62/394,046 2016-09-13
US201662436356P 2016-12-19 2016-12-19
US62/436,356 2016-12-19
US201762460868P 2017-02-19 2017-02-19
US62/460,868 2017-02-19
US201762491071P 2017-04-27 2017-04-27
US62/491,071 2017-04-27
PCT/US2017/051414 WO2018053040A1 (en) 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131

Publications (2)

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JP2019531286A true JP2019531286A (ja) 2019-10-31
JP2019531286A5 JP2019531286A5 (enExample) 2020-10-22

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JP2019513922A Pending JP2019531286A (ja) 2016-09-13 2017-09-13 Ｃｈｓ−１３１による多発性硬化症の治療

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US (1) US20190224186A1 (enExample)
EP (1) EP3512512A4 (enExample)
JP (1) JP2019531286A (enExample)
KR (1) KR20190064583A (enExample)
CN (1) CN110461318A (enExample)
AU (1) AU2017326261A1 (enExample)
BR (1) BR112019004791A2 (enExample)
CA (1) CA3036694A1 (enExample)
IL (1) IL265259A (enExample)
MX (1) MX2019002901A (enExample)
SG (1) SG10202102198RA (enExample)
WO (1) WO2018053040A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2016506956A (ja) * 2013-01-30 2016-03-07 インテクリン・セラピユーテイクス・インコーポレイテツド 多発性硬化症を治療するためのＰＰＡＲγアゴニスト

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015004564A (es) * 2012-10-12 2015-07-21 Teva Pharma Laquinimod para producir el daño talamico en la esclerosis multiple.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2016506956A (ja) * 2013-01-30 2016-03-07 インテクリン・セラピユーテイクス・インコーポレイテツド 多発性硬化症を治療するためのＰＰＡＲγアゴニスト

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BRAIN, vol. 122, JPN6021025537, 1999, pages 871 - 882, ISSN: 0004870728 *
CLINICALTRIALS.GOV ARCHIVE NCT02638038 ON 2015_12_20, ２０１５年１２月２０日，RETRIEVED FROM THE INT, JPN6021025539, 20 December 2015 (2015-12-20), ISSN: 0004870727 *
甲南女子大学研究紀要第２号 看護学・リハビリテーション学編, JPN6022014978, 2009, pages 107 - 112, ISSN: 0004870729 *

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Publication number Publication date
CN110461318A (zh) 2019-11-15
IL265259A (en) 2019-05-30
EP3512512A1 (en) 2019-07-24
CA3036694A1 (en) 2018-03-22
KR20190064583A (ko) 2019-06-10
EP3512512A4 (en) 2020-06-03
AU2017326261A1 (en) 2019-04-04
US20190224186A1 (en) 2019-07-25
BR112019004791A2 (pt) 2019-06-04
WO2018053040A1 (en) 2018-03-22
MX2019002901A (es) 2019-09-26
SG10202102198RA (en) 2021-04-29

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