JP2019530728A5 - - Google Patents
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- JP2019530728A5 JP2019530728A5 JP2019520627A JP2019520627A JP2019530728A5 JP 2019530728 A5 JP2019530728 A5 JP 2019530728A5 JP 2019520627 A JP2019520627 A JP 2019520627A JP 2019520627 A JP2019520627 A JP 2019520627A JP 2019530728 A5 JP2019530728 A5 JP 2019530728A5
- Authority
- JP
- Japan
- Prior art keywords
- recipient
- transplantation
- antibody
- composition
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022020361A JP2022051954A (ja) | 2016-10-12 | 2022-02-14 | 感作レシピエントの腎移植における抗体関連型拒絶反応の予防における抗ｃ５抗体の有効性 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662407167P | 2016-10-12 | 2016-10-12 | |
| US62/407,167 | 2016-10-12 | ||
| PCT/US2017/056268 WO2018071624A1 (en) | 2016-10-12 | 2017-10-12 | Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022020361A Division JP2022051954A (ja) | 2016-10-12 | 2022-02-14 | 感作レシピエントの腎移植における抗体関連型拒絶反応の予防における抗ｃ５抗体の有効性 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019530728A JP2019530728A (ja) | 2019-10-24 |
| JP2019530728A5 true JP2019530728A5 (https=) | 2020-11-12 |
| JP7256741B2 JP7256741B2 (ja) | 2023-04-12 |
Family
ID=60320981
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019520627A Active JP7256741B2 (ja) | 2016-10-12 | 2017-10-12 | 感作レシピエントの腎移植における抗体関連型拒絶反応の予防における抗ｃ５抗体の有効性 |
| JP2022020361A Pending JP2022051954A (ja) | 2016-10-12 | 2022-02-14 | 感作レシピエントの腎移植における抗体関連型拒絶反応の予防における抗ｃ５抗体の有効性 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022020361A Pending JP2022051954A (ja) | 2016-10-12 | 2022-02-14 | 感作レシピエントの腎移植における抗体関連型拒絶反応の予防における抗ｃ５抗体の有効性 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20190276524A1 (https=) |
| EP (1) | EP3526250A1 (https=) |
| JP (2) | JP7256741B2 (https=) |
| WO (1) | WO2018071624A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ631007A (en) | 2014-03-07 | 2015-10-30 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| JP2019517473A (ja) | 2016-05-27 | 2019-06-24 | アレクシオン ファーマシューティカルズ インコーポレイテッドＡｌｅｘｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 難治性全身型重症筋無力症の処置のための方法 |
| ES2984352T3 (es) | 2016-06-14 | 2024-10-29 | Regeneron Pharma | Anticuerpos anti-C5 y usos de los mismos |
| EP3529619B1 (en) | 2016-10-19 | 2021-06-30 | Alexion Pharmaceuticals, Inc. | A method of quantitating unbound c5a in a sample |
| US20200123238A1 (en) * | 2017-04-19 | 2020-04-23 | Alexion Pharmaceuticals, Inc. | Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant |
| SI3658184T1 (sl) | 2017-07-27 | 2024-01-31 | Alexion Pharmaceuticals, Inc., | Formulacije z visoko koncentracijo protiteles proti-C5 |
| CA3080187A1 (en) | 2017-10-26 | 2019-05-02 | Alexion Pharmaceuticals, Inc. | Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) and atypical hemolytic uremic syndrome (ahus) |
| MA51147A (fr) | 2017-12-13 | 2021-03-24 | Regeneron Pharma | Associations d'anticorps anti-c5 et utilisations associées |
| US12404320B2 (en) | 2018-05-31 | 2025-09-02 | Alexion Pharmaceuticals, Inc. | Dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH) in pediatric patients |
| JP7577542B2 (ja) | 2018-06-04 | 2024-11-05 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 小児患者における非典型溶血性尿毒症症候群（ａＨＵＳ）の治療のための抗Ｃ５抗体の用量および投与 |
| WO2020006266A1 (en) | 2018-06-28 | 2020-01-02 | Alexion Pharmaceuticals, Inc. | Methods of producing anti-c5 antibodies |
| CN112996561A (zh) | 2018-10-30 | 2021-06-18 | 亚力兄制药公司 | 用于治疗阵发性睡眠性血红蛋白尿症(pnh)的抗c5抗体的皮下剂量和施用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
| WO1994025591A1 (en) | 1993-04-29 | 1994-11-10 | Unilever N.V. | PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE) |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| US8178098B2 (en) | 2001-04-03 | 2012-05-15 | National Jewish Health | Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies |
| JP6049163B2 (ja) * | 2008-07-21 | 2016-12-21 | イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． | 改善された治療上の特徴のための抗体の構造変異体 |
| PY09026846A (es) | 2008-08-05 | 2015-09-01 | Novartis Ag | Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5 |
| NZ631007A (en) | 2014-03-07 | 2015-10-30 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| CN109310760A (zh) * | 2016-06-07 | 2019-02-05 | 诺华股份有限公司 | 抗c5抗体给药方案 |
-
2017
- 2017-10-12 EP EP17797792.3A patent/EP3526250A1/en not_active Ceased
- 2017-10-12 WO PCT/US2017/056268 patent/WO2018071624A1/en not_active Ceased
- 2017-10-12 US US16/340,453 patent/US20190276524A1/en not_active Abandoned
- 2017-10-12 JP JP2019520627A patent/JP7256741B2/ja active Active
-
2022
- 2022-02-14 JP JP2022020361A patent/JP2022051954A/ja active Pending
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