JP2019529566A5 - - Google Patents

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Publication number
JP2019529566A5
JP2019529566A5 JP2019538108A JP2019538108A JP2019529566A5 JP 2019529566 A5 JP2019529566 A5 JP 2019529566A5 JP 2019538108 A JP2019538108 A JP 2019538108A JP 2019538108 A JP2019538108 A JP 2019538108A JP 2019529566 A5 JP2019529566 A5 JP 2019529566A5
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JP
Japan
Prior art keywords
ubenimex
administered
medicament
inhibitor
agonist
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JP2019538108A
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English (en)
Japanese (ja)
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JP7022136B2 (ja
JP2019529566A (ja
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Priority claimed from PCT/US2017/054087 external-priority patent/WO2018064373A1/en
Publication of JP2019529566A publication Critical patent/JP2019529566A/ja
Publication of JP2019529566A5 publication Critical patent/JP2019529566A5/ja
Application granted granted Critical
Publication of JP7022136B2 publication Critical patent/JP7022136B2/ja
Expired - Fee Related legal-status Critical Current
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JP2019538108A 2016-09-28 2017-09-28 非アルコール性脂肪性肝炎の治療のための方法及び医薬組成物 Expired - Fee Related JP7022136B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662400963P 2016-09-28 2016-09-28
US62/400,963 2016-09-28
US201762460606P 2017-02-17 2017-02-17
US62/460,606 2017-02-17
US201762469722P 2017-03-10 2017-03-10
US62/469,722 2017-03-10
PCT/US2017/054087 WO2018064373A1 (en) 2016-09-28 2017-09-28 Methods and pharmaceutical compositions for the treatment of non-alcoholic steatohepatitis

Publications (3)

Publication Number Publication Date
JP2019529566A JP2019529566A (ja) 2019-10-17
JP2019529566A5 true JP2019529566A5 (https=) 2020-07-02
JP7022136B2 JP7022136B2 (ja) 2022-02-17

Family

ID=61760848

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019538108A Expired - Fee Related JP7022136B2 (ja) 2016-09-28 2017-09-28 非アルコール性脂肪性肝炎の治療のための方法及び医薬組成物

Country Status (6)

Country Link
US (2) US10588880B2 (https=)
EP (1) EP3518918A4 (https=)
JP (1) JP7022136B2 (https=)
KR (1) KR102399254B1 (https=)
CN (1) CN109862888B (https=)
WO (1) WO2018064373A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3518918A4 (en) 2016-09-28 2020-04-22 Eiger Biopharmaceuticals, Inc. METHOD AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS
EP3716975A4 (en) * 2017-11-28 2022-01-12 Eiger Biopharmaceuticals, Inc. METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS
CA3101274A1 (en) * 2018-04-24 2019-10-31 Ph Pharma Co., Ltd. Use of neutrophil elastase inhibitors in liver disease
EP3811937A1 (en) * 2019-10-24 2021-04-28 Sorbonne Universite Compounds for use in the prevention and/or treatment of non-alcoholic fatty liver disease
US11478533B2 (en) 2020-04-27 2022-10-25 Novo Nordisk A/S Semaglutide for use in medicine
AU2022376563A1 (en) 2021-11-01 2023-12-07 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
US4052449A (en) 1974-07-01 1977-10-04 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Biologically active substance, bestatin, and production thereof
US4029547A (en) 1974-07-01 1977-06-14 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Biologically active substance, bestatin, and production thereof
JPH0759507B2 (ja) * 1989-02-23 1995-06-28 日本化薬株式会社 骨髄異形成症候群治療剤
CN1098249C (zh) 1995-06-21 2003-01-08 国家医药管理局四川抗菌素工业研究所 乌比美克及含乌比美克的药物组合物治疗病毒性肝炎的用途
US20080025986A1 (en) 2003-06-06 2008-01-31 Ozes Osman N Methods of Treating Tnf-Mediated Disorders
JP5133071B2 (ja) * 2006-02-09 2013-01-30 第一三共株式会社 抗癌医薬組成物
JP2009109426A (ja) * 2007-10-31 2009-05-21 Sysmex Corp 検体前処理液、ウイルス測定用キット及びウイルス検出方法
WO2012071459A1 (en) 2010-11-22 2012-05-31 The Regents Of The University Of California New indication for use of niacin (nicotinic acid) for treatment, prevention and reversal of fatty liver disease
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
US9233089B2 (en) 2012-03-23 2016-01-12 The Board Of Trustees Of The Leland Stanford Junior University Treatment of pulmonary hypertension with leukotriene inhibitors
CA2819967C (en) 2012-08-31 2016-03-22 Intermune, Inc. Use of pirfenidone concomitantly with ciprofloxacin
CN104902921A (zh) * 2013-01-03 2015-09-09 奥拉姆德有限公司 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物
DK3043865T3 (da) * 2013-09-11 2021-02-01 Univ Claude Bernard Lyon Fremgangsmåder og farmaceutiske sammensætningr til behandlingen af hepatitis b-virusinfektion
US20150111878A1 (en) * 2013-10-22 2015-04-23 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
SI3077047T1 (sl) * 2013-12-04 2019-09-30 Galmed Research & Development Ltd. Soli aramchola
US10500178B2 (en) 2015-03-13 2019-12-10 The Board Of Trustees Of The Leland Stanford Junior University LTB4 inhibition to prevent and treat human lymphedema
CN104784178B (zh) * 2015-05-08 2017-04-12 重庆医科大学 尼克酰胺作为有效成分在制备乙型肝炎治疗药物中的用途
CN104887655A (zh) * 2015-06-12 2015-09-09 上海来益生物药物研究开发中心有限责任公司 乌苯美司在制备用于预防和治疗炎症疾病和与炎症相关的感染疾病的药物制剂中的应用
AU2016348638A1 (en) 2015-11-06 2018-06-07 Gemphire Therapeutics Inc. Gemcabene combinations for the treatment of cardiovascular disease
EP3518918A4 (en) 2016-09-28 2020-04-22 Eiger Biopharmaceuticals, Inc. METHOD AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS
EP3716975A4 (en) 2017-11-28 2022-01-12 Eiger Biopharmaceuticals, Inc. METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS

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