JP2019529502A - アルツハイマー病及びパーキンソン病を処置するための組成物及び方法 - Google Patents

アルツハイマー病及びパーキンソン病を処置するための組成物及び方法 Download PDF

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JP2019529502A
JP2019529502A JP2019517827A JP2019517827A JP2019529502A JP 2019529502 A JP2019529502 A JP 2019529502A JP 2019517827 A JP2019517827 A JP 2019517827A JP 2019517827 A JP2019517827 A JP 2019517827A JP 2019529502 A JP2019529502 A JP 2019529502A
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tablet
syn120
day
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daily dose
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JP2019529502A5 (enExample
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クリストファー ジー． サイレンタイン，
クリストファー ジー． サイレンタイン，
トーマス アール． メルフィット，
トーマス アール． メルフィット，
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バイオティー セラピーズ インコーポレイテッド
バイオティー セラピーズ インコーポレイテッド
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Publication of JP2019529502A publication Critical patent/JP2019529502A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019517827A 2016-09-30 2017-09-29 アルツハイマー病及びパーキンソン病を処置するための組成物及び方法 Pending JP2019529502A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662402357P 2016-09-30 2016-09-30
US62/402,357 2016-09-30
PCT/US2017/054473 WO2018064559A1 (en) 2016-09-30 2017-09-29 Compositions and methods for treating alzheimer's disease and parkinson's disease

Publications (2)

Publication Number Publication Date
JP2019529502A true JP2019529502A (ja) 2019-10-17
JP2019529502A5 JP2019529502A5 (enExample) 2020-11-12

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JP2019517827A Pending JP2019529502A (ja) 2016-09-30 2017-09-29 アルツハイマー病及びパーキンソン病を処置するための組成物及び方法

Country Status (10)

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US (3) US10314798B2 (enExample)
EP (1) EP3518914A4 (enExample)
JP (1) JP2019529502A (enExample)
AR (1) AR109760A1 (enExample)
AU (2) AU2017337053B2 (enExample)
CA (1) CA3037059A1 (enExample)
IL (1) IL265656A (enExample)
MX (2) MX387961B (enExample)
TW (1) TWI753952B (enExample)
WO (1) WO2018064559A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023500904A (ja) * 2019-11-04 2023-01-11 シンクルス・ファーマ・ホールディング・アクチエボラグ Ｘ８４２の経口製剤

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018064559A1 (en) 2016-09-30 2018-04-05 Biotie Therapies, Inc. Compositions and methods for treating alzheimer's disease and parkinson's disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060069094A1 (en) * 2004-09-30 2006-03-30 Roche Palo Alto Llc Compositions and methods for treating cognitive disorders
US20060167255A1 (en) * 2004-12-21 2006-07-27 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof
US20080015256A1 (en) * 2006-06-20 2008-01-17 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof

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CA2368083A1 (en) * 1999-04-06 2000-10-12 Sepracor Inc. Derivatives of venlafaxine and methods of preparing and using the same
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
FR2974102B1 (fr) * 2011-04-13 2014-08-22 Rhodia Operations Composition polyamide stabilisee
WO2015173133A1 (en) * 2014-05-12 2015-11-19 Chiesi Farmaceutici S.P.A. Formulations and methods of treating alzheimer's disease and other proteinopathies by combination therapy
WO2018064559A1 (en) 2016-09-30 2018-04-05 Biotie Therapies, Inc. Compositions and methods for treating alzheimer's disease and parkinson's disease

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060069094A1 (en) * 2004-09-30 2006-03-30 Roche Palo Alto Llc Compositions and methods for treating cognitive disorders
US20060167255A1 (en) * 2004-12-21 2006-07-27 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof
US20080293751A1 (en) * 2004-12-21 2008-11-27 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof
US20120088837A1 (en) * 2004-12-21 2012-04-12 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof
US20080015256A1 (en) * 2006-06-20 2008-01-17 Roche Palo Alto Llc Tetralin and indane derivatives and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, JPN6021038083, 2010, pages 3436 - 3440, ISSN: 0004602537 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023500904A (ja) * 2019-11-04 2023-01-11 シンクルス・ファーマ・ホールディング・アクチエボラグ Ｘ８４２の経口製剤
JP7681819B2 (ja) 2019-11-04 2025-05-23 シンクルス・ファーマ・ホールディング・アクチエボラグ・パブリーク Ｘ８４２の経口製剤

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Publication number Publication date
AU2021277698A1 (en) 2021-12-23
MX2019003720A (es) 2019-09-19
MX2021014093A (es) 2021-12-10
US20180092868A1 (en) 2018-04-05
AU2017337053A1 (en) 2019-04-04
AU2017337053B2 (en) 2021-09-02
EP3518914A4 (en) 2020-06-10
TWI753952B (zh) 2022-02-01
US10973784B2 (en) 2021-04-13
US20210177783A1 (en) 2021-06-17
US20190142771A1 (en) 2019-05-16
WO2018064559A1 (en) 2018-04-05
MX387961B (es) 2025-03-19
US10314798B2 (en) 2019-06-11
AR109760A1 (es) 2019-01-23
TW201813638A (zh) 2018-04-16
CA3037059A1 (en) 2018-04-05
IL265656A (en) 2019-05-30
EP3518914A1 (en) 2019-08-07

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