JP2019529501A5 - - Google Patents
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- Publication number
- JP2019529501A5 JP2019529501A5 JP2019517823A JP2019517823A JP2019529501A5 JP 2019529501 A5 JP2019529501 A5 JP 2019529501A5 JP 2019517823 A JP2019517823 A JP 2019517823A JP 2019517823 A JP2019517823 A JP 2019517823A JP 2019529501 A5 JP2019529501 A5 JP 2019529501A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- thiolated
- nitrofatty
- kidney disease
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404368P | 2016-10-05 | 2016-10-05 | |
| US62/404,368 | 2016-10-05 | ||
| PCT/US2017/055149 WO2018067705A1 (en) | 2016-10-05 | 2017-10-04 | Reversibly protected thiolated electrophilic fatty acids as prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019529501A JP2019529501A (ja) | 2019-10-17 |
| JP2019529501A5 true JP2019529501A5 (https=) | 2020-11-12 |
Family
ID=61832194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517823A Pending JP2019529501A (ja) | 2016-10-05 | 2017-10-04 | 可逆的に保護された、チオレート化求電子性脂肪酸としてのプロドラッグ |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10744106B2 (https=) |
| EP (1) | EP3522884B1 (https=) |
| JP (1) | JP2019529501A (https=) |
| CN (1) | CN109803648A (https=) |
| CA (1) | CA3039376A1 (https=) |
| ES (1) | ES2982757T3 (https=) |
| WO (1) | WO2018067705A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10765652B2 (en) | 2016-10-05 | 2020-09-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Reversible nitroxide derivatives of nitroalkenes that mediate nitrosating and alkylating reactions |
| CN112996493A (zh) | 2018-11-14 | 2021-06-18 | 高等教育联邦系统-匹兹堡大学 | 作为rad51抑制剂的亲电试剂和亲电前药 |
| WO2021242758A1 (en) * | 2020-05-26 | 2021-12-02 | Imara Inc. | Improved nitro-fatty acid oral dose regimens |
| CN118845745B (zh) * | 2024-09-25 | 2024-12-17 | 浙江大学医学院附属第二医院 | 辛酸钠在制备治疗脓毒症药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679224A1 (en) | 2007-08-01 | 2014-01-01 | University of Pittsburgh of the Commonwealth System of Higher Education | Nitro oleic acid modulation of type II diabetes |
| WO2010014889A2 (en) | 2008-08-01 | 2010-02-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Nitro fatty acids as regiomers and related mimetics |
| EP2459189A4 (en) | 2009-07-31 | 2013-01-16 | Univ Pittsburgh | FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS |
| EP2809317A4 (en) | 2012-02-03 | 2015-07-22 | Univ Pittsburgh | FATTY ACIDS AS ANTI-INFLAMMATORY ACTIVE SUBSTANCES |
| EP3440045B1 (en) | 2016-03-04 | 2025-08-20 | University of Pittsburgh- Of the Commonwealth System of Higher Education | Prevention, treatment and reversal of disease using therapeutically effective amounts of dicarboxylic acid compounds |
| US10765652B2 (en) | 2016-10-05 | 2020-09-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Reversible nitroxide derivatives of nitroalkenes that mediate nitrosating and alkylating reactions |
-
2017
- 2017-10-04 JP JP2019517823A patent/JP2019529501A/ja active Pending
- 2017-10-04 EP EP17859121.0A patent/EP3522884B1/en active Active
- 2017-10-04 CN CN201780062044.9A patent/CN109803648A/zh active Pending
- 2017-10-04 ES ES17859121T patent/ES2982757T3/es active Active
- 2017-10-04 US US16/339,702 patent/US10744106B2/en active Active
- 2017-10-04 WO PCT/US2017/055149 patent/WO2018067705A1/en not_active Ceased
- 2017-10-04 CA CA3039376A patent/CA3039376A1/en active Pending
-
2020
- 2020-07-23 US US16/937,263 patent/US20200352890A1/en not_active Abandoned
-
2023
- 2023-05-22 US US18/200,344 patent/US20230321022A1/en active Pending
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