JP2019528082A5 - - Google Patents
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- JP2019528082A5 JP2019528082A5 JP2019517135A JP2019517135A JP2019528082A5 JP 2019528082 A5 JP2019528082 A5 JP 2019528082A5 JP 2019517135 A JP2019517135 A JP 2019517135A JP 2019517135 A JP2019517135 A JP 2019517135A JP 2019528082 A5 JP2019528082 A5 JP 2019528082A5
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- JP
- Japan
- Prior art keywords
- domain
- antibody
- fusion protein
- antigen
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021088589A JP2021143186A (ja) | 2016-06-08 | 2021-05-26 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
| JP2024087108A JP2024112978A (ja) | 2016-06-08 | 2024-05-29 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610404956 | 2016-06-08 | ||
| CN201610404956.7 | 2016-06-08 | ||
| PCT/CN2017/087620 WO2017211321A1 (zh) | 2016-06-08 | 2017-06-08 | 增强激动型抗体活性的抗体重链恒定区序列 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021088589A Division JP2021143186A (ja) | 2016-06-08 | 2021-05-26 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019528082A JP2019528082A (ja) | 2019-10-10 |
| JP2019528082A5 true JP2019528082A5 (enExample) | 2019-11-21 |
Family
ID=60578403
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517135A Pending JP2019528082A (ja) | 2016-06-08 | 2017-06-08 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
| JP2021088589A Pending JP2021143186A (ja) | 2016-06-08 | 2021-05-26 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
| JP2024087108A Pending JP2024112978A (ja) | 2016-06-08 | 2024-05-29 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021088589A Pending JP2021143186A (ja) | 2016-06-08 | 2021-05-26 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
| JP2024087108A Pending JP2024112978A (ja) | 2016-06-08 | 2024-05-29 | アゴニスト抗体の活性を増強する抗体重鎖定常領域配列 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12145993B2 (enExample) |
| EP (1) | EP3470424B1 (enExample) |
| JP (3) | JP2019528082A (enExample) |
| CN (2) | CN107474136B (enExample) |
| WO (1) | WO2017211321A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240110000A (ko) | 2015-06-30 | 2024-07-12 | 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 | Btla 융합 단백질 작용제 및 이의 용도 |
| WO2017211321A1 (zh) * | 2016-06-08 | 2017-12-14 | 上海交通大学医学院 | 增强激动型抗体活性的抗体重链恒定区序列 |
| CA3085472A1 (en) * | 2017-12-19 | 2019-06-27 | The Rockefeller University | Human igg fc domain variants with improved effector function |
| CN109970856B (zh) | 2017-12-27 | 2022-08-23 | 信达生物制药(苏州)有限公司 | 抗lag-3抗体及其用途 |
| KR102813744B1 (ko) * | 2017-12-27 | 2025-05-28 | 브리스톨-마이어스 스큅 컴퍼니 | 항-cd40 항체 및 그의 용도 |
| CN110144009B (zh) * | 2018-02-14 | 2020-01-21 | 上海洛启生物医药技术有限公司 | Cd47单域抗体及其用途 |
| KR20210096167A (ko) * | 2018-11-28 | 2021-08-04 | 브리스톨-마이어스 스큅 컴퍼니 | 변형된 중쇄 불변 영역을 포함하는 항체 |
| TWI756621B (zh) * | 2019-01-25 | 2022-03-01 | 大陸商信達生物製藥(蘇州)有限公司 | 新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體 |
| CA3136491A1 (en) * | 2019-04-10 | 2020-10-15 | Nankai University | Anti-cd40 antibodies and uses thereof |
| CN110981958B (zh) * | 2019-08-23 | 2020-10-20 | 四川大学华西医院 | 一种pd-l1抗体 |
| CN112592404B (zh) * | 2019-09-20 | 2023-07-25 | 上海交通大学医学院 | 抗体活性改造及其筛选方法 |
| CN110862455B (zh) * | 2019-12-03 | 2021-12-21 | 源道隆(苏州)医学科技有限公司 | 可结合cd47的多肽及其应用 |
| AU2020398327A1 (en) | 2019-12-03 | 2022-07-14 | Evotec International Gmbh | Interferon-associated antigen binding proteins and uses thereof |
| BR112022010757A2 (pt) * | 2019-12-03 | 2022-08-16 | Shanghai Jiao Tong Univ School Of Medicine | Região de anticorpo fc com afinidade de ligação aumentada para fc-gama-riib. |
| LT4157876T (lt) | 2020-05-26 | 2024-10-25 | Boehringer Ingelheim International Gmbh | Anti-pd-1 antikūnai |
| CN114591428B (zh) * | 2020-12-04 | 2024-05-28 | 上海交通大学医学院 | 抗Dsg1抗体及其应用 |
| KR102671409B1 (ko) * | 2021-03-02 | 2024-05-31 | 진화섭 | Cd30을 발현하는 세포에 독성을 나타내는 재조합 단백질 및 이를 유효성분으로 포함하는 암의 치료용 약학적 조성물 |
| KR20250108092A (ko) * | 2024-01-02 | 2025-07-15 | 젬파마테크 컴퍼니 리미티드 | 인간화 항체를 생성하는 동물 모델 및 그 제작 방법 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| US7388079B2 (en) * | 2002-11-27 | 2008-06-17 | The Regents Of The University Of California | Delivery of pharmaceutical agents via the human insulin receptor |
| BRPI0510674A (pt) | 2004-07-15 | 2007-12-26 | Xencor Inc | variantes fc otimizadas |
| MX2007001559A (es) * | 2004-08-03 | 2007-04-10 | Transtech Pharma Inc | Proteinas de fusion de receptor para productos finales glicados avanzados y metodos de uso. |
| WO2007046834A2 (en) * | 2004-12-22 | 2007-04-26 | Centocor, Inc. | Glp-1 agonists, compositions, methods and uses |
| WO2007067828A2 (en) * | 2005-10-24 | 2007-06-14 | Centocor, Inc. | Glp-2 mimetibodies, polypeptides, compositions, methods and uses |
| JP5694921B2 (ja) * | 2009-04-20 | 2015-04-01 | 協和発酵キリン株式会社 | アミノ酸変異が導入されたIgG2を有する抗体 |
| CA2822366A1 (en) | 2010-12-23 | 2012-06-28 | Janssen Biotech, Inc. | Active protease-resistant antibody fc mutants |
| EP3604330A1 (en) * | 2011-02-25 | 2020-02-05 | Chugai Seiyaku Kabushiki Kaisha | Fcgammariib-specific fc antibody |
| EP2537864B1 (en) * | 2011-06-24 | 2019-08-07 | Laboratoire Français du Fractionnement et des Biotechnologies | Fc variants with reduced effector functions |
| EP2762493B1 (en) * | 2011-09-30 | 2021-06-09 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
| KR102475951B1 (ko) * | 2012-02-24 | 2022-12-08 | 추가이 세이야쿠 가부시키가이샤 | FcγRIIB를 매개로 항원의 소실을 촉진하는 항원 결합 분자 |
| KR20150013503A (ko) * | 2012-05-11 | 2015-02-05 | 머크 샤프 앤드 돔 코포레이션 | 표면 앵커링된 경쇄 미끼 항체 디스플레이 시스템 |
| TWI855488B (zh) * | 2012-08-24 | 2024-09-11 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
| EP2914627B1 (en) | 2012-10-30 | 2021-04-07 | Apexigen, Inc. | Anti-cd40 antibodies and methods of use |
| TWI635098B (zh) * | 2013-02-01 | 2018-09-11 | 再生元醫藥公司 | 含嵌合恆定區之抗體 |
| KR20160006168A (ko) * | 2013-03-18 | 2016-01-18 | 바이오서오엑스 프로덕스 비.브이. | 인간화 항-cd134(ox40) 항체 및 이의 용도 |
| JP6633520B2 (ja) * | 2013-11-12 | 2020-01-22 | オージーディー2 ファーマ | プロアポトーシス活性を有するヒトigg1由来抗体 |
| JOP20200096A1 (ar) * | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| AU2015248785A1 (en) * | 2014-04-16 | 2016-11-24 | Ucb Biopharma Sprl | Multimeric Fc proteins |
| SMT202100116T1 (it) | 2014-05-28 | 2021-05-07 | Agenus Inc | Anticorpi anti-gitr e metodi di utilizzo degli stessi |
| US20170196971A1 (en) * | 2014-06-05 | 2017-07-13 | The Board Of Trustees Of The University Of Arkansas | Antibody guided vaccines and methods of use for generation of rapid mature immune responses |
| DK3221363T3 (da) * | 2014-11-21 | 2020-08-10 | Bristol Myers Squibb Co | Antistoffer mod cd73 og anvendelser deraf |
| HRP20201756T8 (hr) * | 2014-11-21 | 2021-08-20 | Bristol-Myers Squibb Company | Antitijela koja sadrže modificirane regije teškog lanca |
| BR112018010172A2 (pt) * | 2015-11-19 | 2018-11-21 | Bristol Myers Squibb Co | anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos |
| WO2017211321A1 (zh) * | 2016-06-08 | 2017-12-14 | 上海交通大学医学院 | 增强激动型抗体活性的抗体重链恒定区序列 |
| CN108623686A (zh) | 2017-03-25 | 2018-10-09 | 信达生物制药(苏州)有限公司 | 抗ox40抗体及其用途 |
| BR112022010757A2 (pt) * | 2019-12-03 | 2022-08-16 | Shanghai Jiao Tong Univ School Of Medicine | Região de anticorpo fc com afinidade de ligação aumentada para fc-gama-riib. |
| CN115461122A (zh) * | 2020-05-01 | 2022-12-09 | 博尔特生物治疗药物有限公司 | 抗dectin-2抗体 |
| CN114106174A (zh) * | 2020-08-27 | 2022-03-01 | 苏州景涞医疗科技有限公司 | 低毒性抗ox40抗体、其药物组合物及应用 |
-
2017
- 2017-06-08 WO PCT/CN2017/087620 patent/WO2017211321A1/zh not_active Ceased
- 2017-06-08 EP EP17809760.6A patent/EP3470424B1/en active Active
- 2017-06-08 US US16/308,156 patent/US12145993B2/en active Active
- 2017-06-08 JP JP2019517135A patent/JP2019528082A/ja active Pending
- 2017-06-08 CN CN201710429281.6A patent/CN107474136B/zh active Active
- 2017-06-08 CN CN202210729123.3A patent/CN115304669A/zh active Pending
-
2021
- 2021-05-26 JP JP2021088589A patent/JP2021143186A/ja active Pending
-
2024
- 2024-05-29 JP JP2024087108A patent/JP2024112978A/ja active Pending
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