JP2019526560A5 - - Google Patents

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Publication number
JP2019526560A5
JP2019526560A5 JP2019510659A JP2019510659A JP2019526560A5 JP 2019526560 A5 JP2019526560 A5 JP 2019526560A5 JP 2019510659 A JP2019510659 A JP 2019510659A JP 2019510659 A JP2019510659 A JP 2019510659A JP 2019526560 A5 JP2019526560 A5 JP 2019526560A5
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JP
Japan
Prior art keywords
cancer
substituted
tumor
arylalkyl
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019510659A
Other languages
English (en)
Japanese (ja)
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JP2019526560A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/048581 external-priority patent/WO2018039544A1/en
Publication of JP2019526560A publication Critical patent/JP2019526560A/ja
Publication of JP2019526560A5 publication Critical patent/JP2019526560A5/ja
Pending legal-status Critical Current

Links

JP2019510659A 2016-08-25 2017-08-25 グルタミナーゼ阻害剤との併用療法 Pending JP2019526560A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662379604P 2016-08-25 2016-08-25
US62/379,604 2016-08-25
PCT/US2017/048581 WO2018039544A1 (en) 2016-08-25 2017-08-25 Combination therapy with glutaminase inhibitors

Publications (2)

Publication Number Publication Date
JP2019526560A JP2019526560A (ja) 2019-09-19
JP2019526560A5 true JP2019526560A5 (enExample) 2020-10-01

Family

ID=61240223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019510659A Pending JP2019526560A (ja) 2016-08-25 2017-08-25 グルタミナーゼ阻害剤との併用療法

Country Status (12)

Country Link
US (2) US10278968B2 (enExample)
EP (1) EP3503886A4 (enExample)
JP (1) JP2019526560A (enExample)
KR (1) KR20190040302A (enExample)
CN (1) CN110139649A (enExample)
AU (1) AU2017315446A1 (enExample)
BR (1) BR112019003533A2 (enExample)
CA (1) CA3034890A1 (enExample)
EA (1) EA201990567A1 (enExample)
MX (1) MX2019002108A (enExample)
SG (1) SG11201901389XA (enExample)
WO (1) WO2018039544A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015010955A2 (pt) 2012-11-16 2017-07-11 Calithera Biosciences Inc inibidores de glutaminase heterocíclica
MX2017001620A (es) 2014-08-07 2017-05-10 Calithera Biosciences Inc Formas cristalinas de inhibidores de glutaminasa.
AU2016246521B2 (en) 2015-04-06 2020-07-09 Calithera Biosciences, Inc. Treatment of lung cancer with inhibitors of glutaminase
EP3359150A4 (en) 2015-10-05 2019-11-06 Calithera Biosciences, Inc. COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS AND IMMUNO-ONCOLOGICAL AGENTS
KR20190040302A (ko) 2016-08-25 2019-04-17 칼리테라 바이오사이언시즈, 인코포레이티드 글루타미나제 억제제와의 병용 요법
US10195197B2 (en) 2016-08-25 2019-02-05 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
US11590122B2 (en) 2021-02-19 2023-02-28 Slayback Pharma Llc Pharmaceutical compositions of cabozantinib
KR20230001587A (ko) * 2021-06-28 2023-01-05 연세대학교 산학협력단 암의 예방 또는 치료용 약학 조성물

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US6451828B1 (en) 2000-08-10 2002-09-17 Elan Pharmaceuticals, Inc. Selective inhibition of glutaminase by bis-thiadiazoles
AU2002305926A1 (en) 2001-02-05 2002-10-08 Exegenics Inc. Cysteine protease inhibitors
ES2367311T3 (es) 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
KR101325374B1 (ko) 2008-02-19 2013-11-08 가부시키가이샤 오츠까 세이야꾸 고죠 신체 기능의 회복에 유용한 경구 또는 경장 조성물
WO2011143160A2 (en) 2010-05-10 2011-11-17 The Johns Hopkins University Metabolic inhibitor against tumors having an idh mutation
US10064885B2 (en) 2010-07-09 2018-09-04 Massachusetts Institute Of Technology Metabolic gene, enzyme, and flux targets for cancer therapy
WO2012068512A1 (en) 2010-11-18 2012-05-24 Deuteria Pharmaceuticals Llc 3-deutero-pomalidomide
CN103030597B (zh) 2011-09-30 2014-10-01 南昌滨西科技有限公司 肾脏型谷氨酰胺酶抑制剂及其制备方法和用途
US8604016B2 (en) 2011-11-21 2013-12-10 Calithera Biosciences Inc. Heterocyclic inhibitors of glutaminase
HRP20192144T1 (hr) * 2011-11-21 2020-02-21 Calithera Biosciences Inc. Heterociklični inhibitori glutaminaze
EP2892537A1 (en) 2012-09-10 2015-07-15 Celgene Corporation Methods for the treatment of locally advanced breast cancer
BR112015010955A2 (pt) 2012-11-16 2017-07-11 Calithera Biosciences Inc inibidores de glutaminase heterocíclica
MX369691B (es) 2012-11-21 2019-11-19 Agios Pharmaceuticals Inc Inhibidores de glutaminasa y métodos de empleo.
WO2014079011A1 (en) * 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
CA2892817A1 (en) 2012-12-03 2014-06-12 Calithera Biosciences Inc. Treatment of cancer with heterocyclic inhibitors of glutaminase
WO2015061432A1 (en) 2013-10-25 2015-04-30 Calithera Biosciences, Inc. Treatment of viral infections with inhibitors of glutaminase
EA201690746A1 (ru) 2013-10-25 2016-12-30 Фармасайкликс Элэлси Лечение с применением ингибиторов тирозинкиназы брутона и иммунотерапии
US20150258082A1 (en) 2014-03-14 2015-09-17 Francesco Parlati Combination therapy with glutaminase inhibitors
US10221459B2 (en) 2014-05-13 2019-03-05 Case Western Reserve University Compositions and methods of treating cancer harboring PIKC3A mutations
SG11201610333VA (en) 2014-06-13 2017-01-27 Calithera Biosciences Inc Combination therapy with glutaminase inhibitors
WO2016004418A1 (en) * 2014-07-03 2016-01-07 Board Of Regents, University Of Texas System Glutaminase inhibitor therapy
WO2016014890A1 (en) 2014-07-24 2016-01-28 Calithera Biosciences, Inc. Treatment of multiple myeloma with heterocyclic inhibitors of glutaminase
MX2017001620A (es) 2014-08-07 2017-05-10 Calithera Biosciences Inc Formas cristalinas de inhibidores de glutaminasa.
WO2016054388A1 (en) 2014-10-03 2016-04-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Glutaminase inhibitors
WO2016077632A2 (en) * 2014-11-13 2016-05-19 Buck Institute For Research On Aging Inhibition of proline catabolism for the treatment of cancer and other therapeutic applications
BR112017020780A2 (pt) 2015-03-30 2018-06-26 Calithera Biosciences Inc métodos de administração de inibidores de glutaminase
AU2016246521B2 (en) 2015-04-06 2020-07-09 Calithera Biosciences, Inc. Treatment of lung cancer with inhibitors of glutaminase
KR20190040302A (ko) 2016-08-25 2019-04-17 칼리테라 바이오사이언시즈, 인코포레이티드 글루타미나제 억제제와의 병용 요법
US10195197B2 (en) 2016-08-25 2019-02-05 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
WO2018039442A1 (en) 2016-08-25 2018-03-01 Calithera Biosciences, Inc. Treatment of cancer with inhibitors of glutaminase

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